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Method and system for non-invasive blood glucose detection utilizing spectral data of one or more components other than glucose

  • US 10,542,919 B2
  • Filed: 03/20/2009
  • Issued: 01/28/2020
  • Est. Priority Date: 03/25/2008
  • Status: Active Grant
First Claim
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1. A method for detecting blood glucose in a biological sample, comprising:

  • illuminating a biological sample with a light source;

    collecting transmitted, transflected or reflected light from the sample with a detector;

    generating spectral data, having peaks and valleys, of one or more blood components in the sample other than blood glucose in a spectral data analysis device; and

    analyzing the spectral data of the one or more blood components, wherein the one or more blood components are non-blood glucose, to provide a blood glucose measurement with the spectral data analysis device by measuring light absorption based on the peaks and the valleys of the spectral data, which excludes an interference of a measurement by fat, muscle, and interstitial fluid, without analyzing a glucose signal, wherein the light absorption measured of the one or more blood components that are non-blood glucose contains a change of an absorption amount that is induced by an amount of a presence of the blood glucose which is used to indirectly determine a concentration of the blood glucose.

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