Method and system for non-invasive blood glucose detection utilizing spectral data of one or more components other than glucose
First Claim
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1. A method for detecting blood glucose in a biological sample, comprising:
- illuminating a biological sample with a light source;
collecting transmitted, transflected or reflected light from the sample with a detector;
generating spectral data, having peaks and valleys, of one or more blood components in the sample other than blood glucose in a spectral data analysis device; and
analyzing the spectral data of the one or more blood components, wherein the one or more blood components are non-blood glucose, to provide a blood glucose measurement with the spectral data analysis device by measuring light absorption based on the peaks and the valleys of the spectral data, which excludes an interference of a measurement by fat, muscle, and interstitial fluid, without analyzing a glucose signal, wherein the light absorption measured of the one or more blood components that are non-blood glucose contains a change of an absorption amount that is induced by an amount of a presence of the blood glucose which is used to indirectly determine a concentration of the blood glucose.
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Abstract
A method and system for detecting glucose in a biological sample is disclosed. This includes illuminating a biological sample with a light source, collecting transmitted, transflected or reflected light from the sample with a detector, generating spectral data of one or more components in the sample other than glucose in a spectral data analysis device, and analyzing the spectral data of the one or more components, sufficient to provide a glucose measurement from the spectral data of the one or more components other than glucose with the spectral data analysis device.
150 Citations
22 Claims
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1. A method for detecting blood glucose in a biological sample, comprising:
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illuminating a biological sample with a light source; collecting transmitted, transflected or reflected light from the sample with a detector; generating spectral data, having peaks and valleys, of one or more blood components in the sample other than blood glucose in a spectral data analysis device; and analyzing the spectral data of the one or more blood components, wherein the one or more blood components are non-blood glucose, to provide a blood glucose measurement with the spectral data analysis device by measuring light absorption based on the peaks and the valleys of the spectral data, which excludes an interference of a measurement by fat, muscle, and interstitial fluid, without analyzing a glucose signal, wherein the light absorption measured of the one or more blood components that are non-blood glucose contains a change of an absorption amount that is induced by an amount of a presence of the blood glucose which is used to indirectly determine a concentration of the blood glucose. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 22)
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12. A system for detecting blood glucose in a biological sample, comprising:
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a light source configured to illuminate a biological sample comprising a plurality of blood components, the blood components comprising blood glucose and at least one blood component other than blood glucose; a detector configured to collect transmitted, transflected or reflected light from the biological sample; and a computing device configured to (1) generate spectral data of one or more blood components in the biological sample, wherein the one or more blood components are non-blood glucose, and (2) analyze the spectral data of the one or more blood components that are non-blood glucose to provide a blood glucose measurement by measuring light absorption based on the peaks and the valleys of the spectral data, which excludes an interference of a measurement by fat, muscle, and interstitial fluid, without analyzing a glucose signal, wherein the light absorption measured of the one or more blood components that are non-blood glucose contains a change of an absorption amount that is induced by an amount of a presence of the blood glucose which is used to indirectly determine a concentration of the blood glucose. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20, 21)
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Specification