System for providing an electrical activity map

• US 10,548,496 B2
• Filed: 02/14/2012
• Issued: 02/04/2020
• Est. Priority Date: 02/17/2011
• Status: Active Grant

• Current Assignee: Koninklijke Philips N.V.
• Original Assignee: Koninklijke Philips N.V.
• Inventors: Gijsbers, Gerardus Henricus Maria, Van Den Brink, Hendrikus Bernardus, Slegt, Sander, Nijhof, Niels
• Primary Examiner(s): Alter, Alyssa M
• Application Number:
  US13/984,313
• Publication Number:
  US 20150038862A1
• Time in Patent Office: 2,912 Days
• Field of Search: 600509
• CPC Class Codes: A61B 2576/023 for the heart
• CPC Class Codes: A61B 5/065 Determining position of the probe employing exclusively positioning means located on or in the probe, e.g. using position sensors arranged on the probe
• CPC Class Codes: A61B 5/25 Bioelectric electrodes therefor
• CPC Class Codes: A61B 5/282 Holders for multiple electrodes for introduction into the body A61B5/287
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61B 5/6805 Vests
• CPC Class Codes: A61B 5/684 Indicating the position of the sensor on the body
• CPC Class Codes: A61B 6/00 Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment instruments measuring radiation intensity for application in the field of nuclear medicine, e.g. in vivo counting, G01T1/161; apparatus for taking X-ray photographs G03B42/02
• CPC Class Codes: A61B 6/4441 the rigid structure being a C-arm or U-arm
• CPC Class Codes: A61B 6/503 for diagnosis of the heart
• CPC Class Codes: A61B 8/0883 for diagnosis of the heart
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00
• CPC Class Codes: A61B 8/4254 using sensors mounted on the probe
• CPC Class Codes: G16H 30/40 for processing medical images, e.g. editing

Abstract

The invention relates to a system for providing an electrical cardiac activity map by means of electrical signals acquired by a plurality of surface electrodes on an outer surface of a living being (6). A cardiac structure position determination unit (12) determines a position of a cardiac structure, in particular, of the epicardial surface, based on provided projection images, wherein an anatomical cardiac model is adapted to the projection images. The projection images may be provided by an x-ray C-arm system (2). An electrical activity map determination unit (13) determines the electrical activity map at the cardiac structure based on the electrical signals, the positions of the plurality of surface electrodes also determined from the projection images, and the determined position of the cardiac structure. This allows determining the electrical activity map at the cardiac structure with high accuracy, without necessarily needing, for instance, an x-ray computed tomography system that would apply a relatively high x-ray radiation dose to the living being. The electrodes may be comprised in a vest (8).

Claims

1. A system for providing an electrical activity map of the heart of a living being by means of electrical signals from the heart acquired by a plurality of surface electrodes on an outer surface of the living being, the system comprising:

a projection images providing unit for providing projection images of the heart and of the plurality of surface electrodes in different directions,

a surface electrodes positions determination unit for determining positions of the plurality of surface electrodes on the outer surface of the living being based on the provided projection images,

a cardiac structure position determination unit for determining a position of a cardiac structure of the living being based on the provided projection images, wherein the cardiac structure position determination unit is configured to adapt an anatomical cardiac model including the cardiac structure to the provided projection images of the heart, in order to determine the position of the cardiac structure, and

an electrical activity map determination unit for determining the electrical activity map at the cardiac structure based on the electrical signals measured on the outer surface of the living being, the determined positions of the plurality of surface electrodes on the outer surface of the living being and the determined position of the cardiac structure.

2. The system of claim 1, wherein the surface electrodes positions determination unit is configured to provide a model distribution of the surface electrodes, to adapt the model distribution to the provided projection images, and to determine the positions of the plurality of surface electrodes from the adapted model distribution.

3. The system as defined in claim 1, wherein the cardiac model is a non-specific cardiac model.

4. The system of claim 3, wherein the non-specific cardiac model is not specific to the heart of the living being.

5. The system as defined in claim 3, wherein the cardiac structure position determination unit is configured to adapt the anatomical cardiac model including the cardiac structure to the provided projection images of the heart by performing at least one of a translation procedure, a rotation procedure and a scaling procedure.

6. The system as defined in claim 1, wherein the projection image providing unit is an x-ray C-arm system.

7. The system of claim 5, wherein the non-specific cardiac model is a segmented heart model comprising an average of a plurality of segmented heart images of a plurality of persons.

8. The system as defined in claim 6, wherein the x-ray C-arm system is configured to perform a single axis C-arm movement or a dual axes C-arm movement.

9. The system as defined in claim 6, wherein the x-ray C-arm system is a monoplane projection system or a biplane projection system.

10. The system as defined in claim 1,

wherein the anatomical cardiac model is a non-patient specific generalized three-dimensional cardiac model,

wherein the projection images providing unit is a C-arc system for providing several two-dimensional x-ray projection images,

wherein the surface electrodes positions determination unit is configured to determine the positions of the plurality of surface electrodes by performing a three-dimensional position modelling based on the several two-dimensional x-ray projection images,

wherein the cardiac structure position determination unit is configured to match the non-patient specific generalized three-dimensional cardiac model with a cardiac contour in selected two-dimensional x-ray projection images from the several two-dimensional x-ray projection images, and

wherein the electrical activity map determination unit is configured to determine the electrical activity map by performing an electrocardiographic mapping on the surface of the matched generalized three-dimensional cardiac model.

11. The system of claim 1, wherein the projection images providing unit is a storage unit in which the projection images are stored.

12. The system of claim 1, wherein the plurality of surface electrodes comprises at least one hundred electrodes, and wherein the electrical activity map determination unit is configured to receive the electrical signals from the at least one hundred electrodes.

13. A method for providing an electrical activity map of the heart of a living being by means of electrical signals from the heart acquired by a plurality of surface electrodes on an outer surface of the living being, the method comprising:

providing projection images of the heart and of the plurality of surface electrodes in different directions by a projection images providing unit,

determining positions of the plurality of surface electrodes on the outer surface of the living being based on the provided projection images,

determining a position of a cardiac structure of the living being based on the provided projection images by adapting an anatomical cardiac model including the cardiac structure to the provided projection images of the heart, in order to determine the position of the cardiac structure,

determining the electrical activity map at the cardiac structure based on the electrical signals measured on the outer surface of the living being, the determined positions of the plurality of electrodes on an outer surface of the living being, and the determined position of the cardiac structure.

14. The method of claim 13, wherein providing projection images of the heart and of the plurality of surface electrodes in different directions by a projection images providing unit comprises:

emitting an x-ray beam from an x-ray source to traverse the electrodes and the heart; and

detecting with an x-ray detector the x-ray beam after the x-ray beam has traversed the electrodes and the heart.

15. The method of claim 14, further comprising rotating the x-ray source and x-ray detector around the living being in a single rotational axis to acquire the projection images in the different directions.

16. The method of claim 14, further comprising rotating the x-ray source and x-ray detector around the living being in two rotational axes to acquire the projection images in the different directions.

17. The method of claim 13, wherein providing projection images of the heart and of the plurality of surface electrodes in different directions by a projection images providing unit comprises:

emitting a first x-ray beam from a first x-ray source to traverse the electrodes and the heart in a first direction;

detecting with a first x-ray detector the first x-ray beam after the first x-ray beam has traversed the electrodes and the heart in the first direction;

emitting a second x-ray beam from a second x-ray source to traverse the electrodes and the heart in a second direction orthogonal to the first direction; and

detecting with a second x-ray detector the first x-ray beam after the first x-ray beam has traversed the electrodes and the heart in the second direction.

18. The method of claim 13, wherein determining positions of the plurality of surface electrodes on the outer surface of the living being based on the provided projection images model distribution of the surface electrodes comprises:

adapting a model distribution of the surface electrodes to the provided projection images; and

determining the positions of the plurality of surface electrodes from the adapted model distribution.

19. The method of claim 13,

wherein the anatomical cardiac model is a non-patient specific generalized three-dimensional cardiac model,

wherein determining the positions of the plurality of surface electrodes on the outer surface of the living being comprises performing a three-dimensional position modelling based on the several two-dimensional x-ray projection images,

wherein adapting the anatomical cardiac model including the cardiac structure to the provided projection images of the heart in order to determine the position of the cardiac structure includes matching the non-patient specific generalized three-dimensional cardiac model with a cardiac contour in selected two-dimensional x-ray projection images from the several two-dimensional x-ray projection images, and

wherein determining the electrical activity map at the cardiac structure includes performing an electrocardiographic mapping on the surface of the matched generalized three-dimensional cardiac model.

20. A non-transitory computer readable medium having stored thereon computer-readable instructions for causing a system to perform a method for providing an electrical activity map of the heart of a living being by means of electrical signals from the heart acquired by a plurality of surface electrodes on an outer surface of the living being, the method comprising:

providing, via a projection images providing unit of the system, projection images of the heart and of the plurality of surface electrodes in different directions,

determining positions of the plurality of surface electrodes based on the provided projection images,

determining a position of a cardiac structure of the living being based on the provided projection images by adapting an anatomical cardiac model including the cardiac structure to the provided projection images of the heart, in order to determine the position of the cardiac structure, and

determining the electrical activity map at the cardiac structure based on the electrical signals measured on the outer surface of the living being, the determined positions of the plurality of electrodes and the determined position of the cardiac structure.