Composition in the form of nano- or micro-emulsion

• US 10,561,587 B2
• Filed: 03/31/2015
• Issued: 02/18/2020
• Est. Priority Date: 04/01/2014
• Status: Expired due to Fees

• Current Assignee: L'Oreal SA
• Original Assignee: L'Oreal SA
• Inventors: Koide, Maki, Bernard, Anne-Laure
• Primary Examiner(s): Gembeh, Shirley V
• Application Number:
  US15/129,961
• Publication Number:
  US 20170156998A1
• Time in Patent Office: 1,785 Days
• CPC Class Codes: A61K 2800/262 Transparent; Translucent
• CPC Class Codes: A61K 2800/596 Mixtures of surface active compounds
• CPC Class Codes: A61K 8/06 Emulsions
• CPC Class Codes: A61K 8/062 Oil-in-water emulsions
• CPC Class Codes: A61K 8/068 Microemulsions
• CPC Class Codes: A61K 8/34 Alcohols
• CPC Class Codes: A61K 8/345 containing more than one hydroxy group
• CPC Class Codes: A61K 8/362 Polycarboxylic acids
• CPC Class Codes: A61K 8/37 Esters of carboxylic acids
• CPC Class Codes: A61K 8/39 Derivatives containing from 2 to 10 oxyalkylene groups
• CPC Class Codes: A61K 8/42 Amides
• CPC Class Codes: A61K 8/45 Derivatives containing from 2 to 10 oxyalkylene groups
• CPC Class Codes: A61K 8/463 containing sulfuric acid derivatives, e.g. sodium lauryl sulfate
• CPC Class Codes: A61K 8/4993 Derivatives containing from 2 to 10 oxyalkylene groups
• CPC Class Codes: A61K 8/68 Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
• CPC Class Codes: A61K 8/73 Polysaccharides
• CPC Class Codes: A61K 8/92 Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
• CPC Class Codes: A61Q 1/14 Preparations for removing make-up
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin

Abstract

The present invention relates to a composition in the form of a nano- or micro-emulsion, comprising: (a) at least one oil; (b) at least one nonionic surfactant with an HLB value of from 8.0 to 14.0, preferably from 9.0 to 13.5, and more preferably from 10.0 to 13.0; (c) at least one ceramide compound; (d) at least one anionic surfactant; and (e) water. The composition can be used as a cosmetic composition and provides an excellent feeling during use and can be transparent or slightly translucent, and is stable over time, even at an elevated temperature.

Claims

1. A composition in the form of a nano- or micro-emulsion, comprising:

(a) at least one oil;

(b) at least one nonionic surfactant with an HLB (Hydrophilic Lipophilic Balance) value ranging from about 8.0 to about 14.0 that is fluid at a temperature less than or equal to 45°

C., chosen from the esters of at least one polyol chosen from polyglycerols comprising from 2 to 12 glycerol units, and of at least one fatty acid comprising at least one saturated or unsaturated, linear or branched C₈-C₂₂ alkyl chain;

(c) at least one ceramide compound;

(d) at least one anionic surfactant; and

(e) water,

wherein the at least one nonionic surfactant with an HLB value ranging from about 8.0 to about 14.0 is chosen from;

polyglyceryl monolaurate or dilaurate comprising 3 to 6 glycerol units;

polyglyceryl mono(iso)stearate comprising 3 to 6 glycerol units;

polyglyceryl monooleate comprising 3 to 6 glycerol units;

or

polyglyceryl dioleate comprising 3 to 6 glycerol units.

2. The composition according to claim 1, wherein the at least one oil is chosen from oils with a molecular weight below about 600 g/mol.

3. The composition according to claim 1, wherein the at least one oil is present in an amount ranging from about 0.1% to about 30% by weight, relative to the total weight of the composition.

4. The composition according to claim 1, wherein the at least one nonionic surfactant with an HLB value ranging from about 8.0 to about 14.0 is present in an amount ranging from about 0.1% to about 30% by weight, relative to the total weight of the composition.

5. The composition according to claim 1, wherein the at least one nonionic surfactant with an HLB value ranging from about 8.0 to about 14.0 and the at least one oil are present in a weight ratio of about 2 or less.

6. The composition according to claim 1, wherein the at least one ceramide compound is chosen from formula (I) below:

7. The composition according to claim 6, wherein R₃ is a C₁₅-C₂₆ α

-hydroxyalkyl radical and the hydroxyl group is optionally esterified by a C₁₆-C₃₀ α

-hydroxy acid.

8. The composition according to claim 1, wherein the at least one ceramide compound is chosen from 2-N-linoleoylaminooctadecane-1,3-diol, 2-N-oleoylaminooctadecane-1,3-diol, 2-N-palmitoylaminooctadecane-1,3-diol, 2-N-stearoylaminooctadecane-1,3-diol, 2-N-behenoylaminooctadecane-1,3-diol, 2-N-[2-hydroxypalmitoyl]aminooctadecane-1,3-diol, 2-N-stearoylaminoocta-decane-1,3,4-triol, 2-N-palmitoylaminohexadecane-1,3-diol, or mixtures thereof.

9. The composition according to claim 1, wherein the at least one ceramide compound is chosen from bis(N-hydroxyethyl-N-cetyl)malonamide, the N-(2-hydroxyethyl)-N-(3-cetyloxy-2-hydroxypropyl)amide of cetylic acid, or N-docosanoyl-N-methyl-D-glucamine.

10. The composition according to claim 1, wherein the at least one ceramide compound is present in an amount ranging from about 0.01% to about 20% by weight, relative to the total weight of the composition.

11. The composition according to claim 1, wherein the weight ratio of the at least one nonionic surfactant with an HLB value ranging from about 8.0 to about 14.0 to the at least one ceramide compound is about 15 or less.

12. The composition according to claim 1, wherein the at least one anionic surfactant is chosen from anionic derivatives of proteins of vegetable origin or of silk proteins, phosphates and alkyl phosphates, carboxylates, sulphosuccinates, amino acid derivatives, alkyl sulphates, alkyl ether sulphates, sulphonates, isethionates, taurates, alkyl sulphoacetates, polypeptides, anionic derivatives of alkyl polyglucosides, or mixtures thereof.

13. The composition according to claim 1, wherein the at least one anionic surfactant is chosen from taurates or glutamates.

14. The composition according to claim 1, wherein the at least one anionic surfactant is present in an amount ranging from about 0.01% to about 20% by weight, relative to the total weight of the composition.

15. The composition according to claim 1, wherein the water is present in an amount ranging from about 40% to about 90% by weight, relative to the total weight of the composition.

16. The composition according to claim 1, further comprising at least one cationic or amphoteric surfactant.

17. The composition according to claim 1, wherein the composition has a turbidity of about 300 NTU or less.

18. The composition according to claim 1, wherein the composition is a cosmetic composition.

19. A cosmetic and/or non-therapeutic process for treating the skin, hair, mucous membranes, nails, eyelashes, eyebrows and/or scalp, comprising:

applying to the skin, hair, mucous membranes, nails, eyelashes, eyebrows, and/or scalp a composition in the form of a nano- or micro-emulsion, the composition comprising;

(a) at least one oil;

(b) at least one nonionic surfactant with an HLB (Hydrophilic Lipophilic Balance) value ranging from about 8.0 to about 14.0 that is fluid at a temperature less than or equal to 45°

C., chosen from the esters of at least one polyol chosen from polyglycerols comprising from 2 to 12 glycerol units, and of at least one fatty acid comprising at least one saturated or unsaturated, linear or branched C₈-C₂₂ alkyl chain;

(c) at least one ceramide compound;

(d) at least one anionic surfactant; and

(e) water;

wherein the at least one nonionic surfactant with an HLB value ranging from about 8.0 to about 14.0 is chosen from;

polyglyceryl monolaurate or dilaurate comprising 3 to 6 glycerol units;

polyglyceryl mono(iso)stearate comprising 3 to 6 glycerol units;

polyglyceryl monooleate comprising 3 to 6 glycerol units;

or

polyglyceryl dioleate comprising 3 to 6 glycerol units.