Apparatus for and method of monitoring blood pressure and wearable device having function of monitoring blood pressure

• US 10,568,527 B2
• Filed: 09/03/2015
• Issued: 02/25/2020
• Est. Priority Date: 09/03/2014
• Status: Active Grant

• Current Assignee: Samsung Electronics Co. Ltd.
• Original Assignee: Samsung Electronics Co. Ltd.
• Inventors: Yoon, Youngzoon, Lee, Jaesoong, Kyoung, Jisoo, Roh, Younggeun, Park, Yeonsang, Baik, Chanwook
• Primary Examiner(s): Hoffa, Angela M
• Application Number:
  US14/844,437
• Publication Number:
  US 20160058300A1
• Time in Patent Office: 1,636 Days
• CPC Class Codes: A61B 2562/0233 Special features of optical sensors or probes classified in A61B5/00
• CPC Class Codes: A61B 2562/046 in a matrix array
• CPC Class Codes: A61B 2562/12 Manufacturing methods specially adapted for producing sensors for in-vivo measurements
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/0059 using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: A61B 5/021 Measuring pressure in heart or blood vessels A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/02438 with portable devices, e.g. worn by the patient
• CPC Class Codes: A61B 5/0261 using optical means, e.g. infrared light
• CPC Class Codes: A61B 5/0295 using plethysmography, i.e. measuring the variations in the volume of a body part as modified by the circulation of blood therethrough, e.g. impedance plethysmography
• CPC Class Codes: A61B 5/6803 Head-worn items, e.g. helmets, masks, headphones or goggles
• CPC Class Codes: A61B 5/681 Wristwatch-type devices
• CPC Class Codes: A61B 5/7235 Details of waveform analysis A61B5/349 takes precedence

Abstract

A method of monitoring a blood pressure includes: emitting a laser to a blood vessel in a body part; detecting, from the body part, laser speckles caused by scattering of the emitted laser; obtaining a bio-signal indicating a change in a volume of the blood vessel by using the detected laser speckles; and estimating a blood pressure based on the obtained bio-signal.

Claims

1. An apparatus for monitoring a blood pressure, the apparatus comprising:

a laser emitter configured to emit a laser towards a blood vessel in a body part using at least one laser diode device to oscillate the laser;

a speckle detector configured to detect, from the body part, laser speckles caused by scattering of the laser that is emitted and reflected from the body part; and

a controller configured to obtain a bio-signal indicating a change in a volume of the blood vessel from the laser speckles and estimate the blood pressure based on the obtained bio-signal,

wherein the speckle detector comprises a plurality of photodetecting devices,

wherein the controller is configured to select a photodetecting device having a highest detection sensitivity, from among the plurality of photodetecting devices, and estimate the blood pressure based on the laser speckles detected by the photodetecting device that is selected,

wherein the detection sensitivity corresponds to a change in an intensity of an optical signal corresponding to a speckle fluctuation of the laser speckles that is received by the speckle detector,

wherein a number of the photodetecting devices for detecting the laser speckles caused by the at least one laser diode device is more than a number of the at least one laser diode device, and

wherein each of the plurality of photodetecting devices are packaged around the at least one laser diode device.

2. The apparatus of claim 1, wherein the controller is further configured to obtain the bio-signal by analyzing the speckle fluctuation of the laser speckles detected by at least one photodetecting device, the speckle fluctuation corresponding to the change in the volume of the blood vessel.

3. The apparatus of claim 2, wherein the obtained bio-signal comprises a photoplethysmogram (PPG) signal that is obtained based on the analyzed speckle fluctuation, and

wherein the detection sensitivity, corresponding to the change in the intensity of the optical signal, corresponds to an average of a waveform amplitude of the PPG signal.

4. The apparatus of claim 1, wherein the controller is further configured to obtain the bio-signal based on a relationship between the intensity of the optical signal corresponding to the speckle fluctuation of the laser speckles that is received by the speckle detector and time.

5. The apparatus of claim 2, wherein the controller is further configured to:

convert a change in the intensity of the optical signal corresponding to the speckle fluctuation of the laser speckles detected for a predetermined period of time after the laser is emitted into a photoplethysmogram (PPG) signal; and

estimate a systolic blood pressure and a diastolic blood pressure based on waveform characteristics of the PPG signal.

6. The apparatus of claim 1, wherein the laser emitter comprises at least one laser diode device configured to oscillate the laser,

wherein the at least one laser diode device and the plurality of photodetecting devices are packaged on a common substrate.

7. The apparatus of claim 6, wherein each of the plurality of photodetecting devices is packaged on the common substrate at a same distance from the at least one laser diode device.

8. The apparatus of claim 7, wherein the plurality of photodetecting devices are symmetrically spaced from the at least one laser diode device.

9. The apparatus of claim 6, further comprising a second substrate stacked on the common substrate, wherein the second substrate includes at least one selected from a first lens through which the emitted laser passes and a second lens through which a laser reflected from the laser speckles passes, and a surface into which the first lens and the second lens are not inserted and which is anti-reflection (AR) coated.

10. The apparatus of claim 9, wherein each of the first lens and the second lens comprises at least one selected from a cylindrical lens and a flat lens.

11. The apparatus of claim 9, wherein the emitted laser and the reflected laser corresponding to the laser speckles are in a same wavelength band.

12. A wearable device configured to monitor a blood pressure, the wearable device comprising:

at least one blood pressure monitoring module configured to measure a blood pressure of a user;

a user interface module configured to provide information about the blood pressure; and

a processor that controls the at least one blood pressuring monitoring module and the user interface module,

wherein each of the at least one blood pressure monitoring module comprises;

a laser emitter configured to emit a laser towards a blood vessel in a body part using at least one laser diode device to oscillate the laser;

a speckle detector configured to detect, from the body part, laser speckles caused by scattering of the laser that is emitted laser and reflected from the body part; and

a controller configured to obtain a bio-signal indicating a change in a volume of the blood vessel from the laser speckles and estimate the blood pressure based on the obtained bio-signal,

wherein the speckle detector comprises a plurality of photodetecting devices,

wherein the controller is configured to select a photodetecting device having a highest detection sensitivity, from among the plurality of photodetecting devices, and estimate the blood pressure based on the laser speckles detected by the photodetecting device that is selected,

wherein the detection sensitivity corresponds to a change in an intensity of an optical signal corresponding to a speckle fluctuation of the laser speckles that is received by the speckle detector,

wherein a number of the photodetecting devices for detecting the laser speckles caused by the at least one laser diode device is more than a number of the at least one laser diode device, and

wherein each of the plurality of photodetecting devices are packaged around the at least one laser diode device.

13. The wearable device of claim 12, wherein the controller is further configured to obtain the bio-signal by analyzing the speckle fluctuation of the laser speckles, the speckle fluctuation corresponding to the change in the volume of the blood vessel,

wherein the speckle fluctuation is analyzed based on a relationship between an intensity of an optical signal that is received by the speckle detector and time.

14. The wearable device of claim 12, wherein the wearable device comprises a wristwatch-type device configured to be worn on a wrist of the user, and

wherein the blood vessel is a radial artery in the wrist.

15. A method of monitoring a blood pressure, the method comprising:

emitting a laser towards a blood vessel in a body part using at least one laser diode device of a laser emitter to oscillate the laser;

detecting by using a speckle detector, from the body part, laser speckles caused by scattering of the laser emitted and reflected from the body part;

obtaining a bio-signal indicating a change in a volume of the blood vessel from the detected laser speckles; and

estimating the blood pressure based on the obtained bio-signal,

wherein the speckle detector comprises a plurality of photodetecting devices,

wherein the estimating comprises selecting a photodetecting device having a highest detection sensitivity, from among the plurality of photodetecting devices, and estimating the blood pressure based on the laser speckles detected by the photodetecting device that is selected, and

wherein the detection sensitivity corresponds to a change in an intensity of an optical signal corresponding to a speckle fluctuation of the laser speckles that is received by the speckle detector,

wherein a number of the photodetecting devices for detecting the laser speckles caused by the at least one laser diode device is more than a number of the at least one laser diode device, and

wherein each of the plurality of photodetecting devices are packaged around the at least one laser diode device.

16. The method of claim 15, wherein the obtaining the bio-signal is performed by analyzing the speckle fluctuation of the laser speckles, the speckle fluctuation corresponding to the change in the volume of the blood vessel,

wherein the speckle fluctuation is analyzed based on a relationship between the intensity of the optical signal that is received by the speckle detector and time.

17. The method of claim 15, wherein the obtaining the bio-signal is performed by converting the change in the intensity of the optical signal corresponding to the speckle fluctuation of the laser speckles detected for a predetermined period of time after the laser is emitted into a photoplethysmogram (PPG) signal, and

the estimating the blood pressure comprises estimating a systolic blood pressure and a diastolic blood pressure based on waveform characteristics of the PPG signal.