Multi-stream data collection system for noninvasive measurement of blood constituents

• US 10,588,554 B2
• Filed: 08/19/2019
• Issued: 03/17/2020
• Est. Priority Date: 07/03/2008
• Status: Active Grant

• Current Assignee: Masimo Corporation
• Original Assignee: Masimo Corporation
• Inventors: Poeze, Jeroen, Lamego, Marcelo, Merritt, Sean, Dalvi, Cristiano, Vo, Hung, Bruinsma, Johannes, Lesmana, Ferdyan, Kiani, Massi Joe E., Olsen, Greg
• Primary Examiner(s): Winakur, Eric F
• Assistant Examiner(s): Liu, Chu Chuan
• Application Number:
  US16/544,713
• Publication Number:
  US 20190365295A1
• Time in Patent Office: 211 Days
• CPC Class Codes: A61B 2562/0233 Special features of optical sensors or probes classified in A61B5/00
• CPC Class Codes: A61B 2562/04 Arrangements of multiple sensors of the same type
• CPC Class Codes: A61B 2562/046 in a matrix array
• CPC Class Codes: A61B 2562/146 for optical coupling
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/02427 Details of sensor
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/1455 using optical sensors, e.g. spectral photometrical oximeters
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor
• CPC Class Codes: A61B 5/4875 Hydration status, fluid retention of the body
• CPC Class Codes: A61B 5/6816 Ear lobe
• CPC Class Codes: A61B 5/6826 Finger
• CPC Class Codes: A61B 5/6829 Foot or ankle
• CPC Class Codes: A61B 5/6838 Clamps or clips
• CPC Class Codes: A61B 5/6843 Monitoring or controlling sensor contact pressure
• CPC Class Codes: A61B 5/70 Means for positioning the patient in relation to the detecting, measuring or recording means
• CPC Class Codes: A61B 5/7275 Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor

Abstract

The present disclosure relates to noninvasive methods, devices, and systems for measuring various blood constituents or analytes, such as glucose. In an embodiment, a light source comprises LEDs and super-luminescent LEDs. The light source emits light at at least wavelengths of about 1610 nm, about 1640 nm, and about 1665 nm. In an embodiment, the detector comprises a plurality of photodetectors arranged in a special geometry comprising one of a substantially linear substantially equal spaced geometry, a substantially linear substantially non-equal spaced geometry, and a substantially grid geometry.

Claims

1. A physiological measurement system comprising:

a physiological sensor device comprising;

a plurality of emitters configured to emit light into tissue of a user;

at least four detectors, wherein each of the at least four detectors has a corresponding window that allows light to pass through to the detector;

a wall that surrounds at least the at least four detectors; and

a cover that operably connects to the wall and that is configured to be located between tissue of the user and the at least four detectors when the physiological sensor device is worn by the user, wherein;

the cover comprises a single protruding convex surface, and

at least a portion of the cover is sufficiently rigid to cause tissue of the user to conform to at least a portion of a shape of the single protruding convex surface when the physiological sensor device is worn by the user; and

a handheld computing device in wireless communication with the physiological sensor device, wherein the handheld computing device comprises;

one or more processors configured to wirelessly receive one or more signals from the physiological sensor device, the one or more signals responsive to at least a physiological parameter of the user;

a touch-screen display configured to provide a user interface,

wherein;

the user interface is configured to display indicia responsive to measurements of the physiological parameter, and

an orientation of the user interface is configurable responsive to a user input; and

a storage device configured to at least temporarily store at least the measurements of the physiological parameter.

2. The physiological measurement system of claim 1, wherein the at least four detectors comprise at least eight detectors.

3. The physiological measurement system of claim 2, wherein at least part of the single protruding convex surface is light permeable to provide at least one optical path to at least one of the at least four detectors.

4. The physiological measurement system of claim 3, wherein the physiological sensor device further comprises:

an at least partially opaque layer blocking one or more optical paths to at least one of the at least four detectors, wherein the at least partially opaque layer comprises the windows that allow light to pass through to the corresponding detectors.

5. The physiological measurement system of claim 4, wherein the physiological sensor device further comprises:

a substrate having a first surface, wherein the at least four detectors are arranged on the first surface.

6. The physiological measurement system of claim 5, wherein:

the wall surrounds at least the at least four detectors on the first surface,

the wall operably connects to the substrate on one side of the wall, and

the wall operably connects to the cover on an opposing side of the wall.

7. The physiological measurement system of claim 6, wherein the wall creates one or more gaps between the first surface of the substrate and a surface of the cover that is interior to the physiological sensor device, and wherein the at least four detectors are positioned on the first surface of the substrate within the one or more gaps.

8. The physiological measurement system of claim 6, wherein the substrate, the wall, and the cover together hermetically seal the at least four detectors.

9. The physiological measurement system of claim 8, wherein a surface of the handheld computing device positions the touch-screen display.

10. The physiological measurement system of claim 9, wherein the physiological parameter comprises at least one of:

pulse rate, glucose, oxygen, oxygen saturation, methemoglobin, total hemoglobin, carboxyhemoglobin, or carbon monoxide.

11. The physiological measurement system of claim 10, wherein the single protruding convex surface protrudes a height between 1 millimeter and 3 millimeters.

12. The physiological measurement system of claim 11, wherein at least one of the detectors is configured to detect light that has been attenuated by tissue of the user.

13. The physiological measurement system of claim 12, wherein the displayed indicia are further responsive to temperature.

14. The physiological measurement system of claim 13, wherein a portion of the physiological sensor device comprises one of at least two sizes, the two sizes intended to be appropriate for larger users and smaller users.

15. The physiological measurement system of claim 14, wherein the at least four detectors are arranged such that a first detector and a second detector of the least four detectors are arranged across from each other on opposite sides of a central point along a first axis, and a third detector and a fourth detector of the least four detectors are arranged across from each other on opposite sides of the central point along a second axis which is different from the first axis.

16. The physiological measurement system of claim 15, wherein the first axis is perpendicular to the second axis, and wherein the first, second, third and fourth detectors form a cross pattern about the central point.

17. The physiological measurement system of claim 16, wherein the single protruding convex surface protrudes a height greater than 2 millimeters and less than 3 millimeters.

18. The physiological measurement system of claim 17, wherein the attenuated light is reflected by the tissue.

19. The physiological measurement system of claim 9, wherein the physiological parameter comprises a state or trend of wellness of the user.

20. A physiological measurement system comprising:

a physiological sensor device comprising;

a plurality of emitters configured to emit light into tissue of a user;

at least four detectors, wherein each of the at least four detectors has a corresponding window that allows light to pass through to the detector;

a wall that surrounds at least the at least four detectors; and

a cover comprising a single protruding convex surface, wherein the single protruding convex surface is configured to be located between tissue of the user and the at least four detectors when the physiological sensor device is worn by the user, wherein at least a portion of the single protruding convex surface is sufficiently rigid to cause tissue of the user to conform to at least a portion of a shape of the single protruding convex surface when the physiological sensor device is worn by the user, and wherein the cover operably connects to the wall; and

a handheld computing device in wireless communication with the physiological sensor device.

21. The physiological measurement system of claim 20, wherein the handheld computing device comprises:

one or more processors configured to wirelessly receive one or more signals from the physiological sensor device, the one or more signals responsive to at least a physiological parameter of the user;

a touch-screen display configured to provide a user interface, wherein;

the user interface is configured to display indicia responsive to measurements of the physiological parameter, and

an orientation of the user interface is configurable responsive to a user input; and

a storage device configured to at least temporarily store at least the measurements of the physiological parameter.

22. The physiological measurement system of claim 21, wherein the at least four detectors comprise at least eight detectors.

23. The physiological measurement system of claim 22, wherein at least part of the single protruding convex surface is light permeable to allow light to reach at least one of the at least four detectors.

24. The physiological measurement system of claim 23, wherein the physiological sensor device further comprises:

an at least partially opaque layer blocking one or more optical paths to at least one of the at least four detectors, wherein the at least partially opaque layer comprises the windows that allow light to pass through to the corresponding detectors.

25. The physiological measurement system of claim 24, wherein the physiological sensor device further comprises:

a substrate having a first surface, wherein the at least four detectors are arranged on the first surface, and wherein the wall surrounds at least the at least four detectors on the first surface,

wherein;

the wall operably connects to the substrate on one side of the wall, and

the wall operably connects to the cover on an opposing side of the wall.

26. The physiological measurement system of claim 25, wherein a surface of the handheld computing device positions the touch-screen display.

27. The physiological measurement system of claim 26, wherein the physiological parameter comprises at least one of:

pulse rate, glucose, oxygen, oxygen saturation, methemoglobin, total hemoglobin, carboxyhemoglobin, carbon monoxide, or a state or trend of wellness of the user.

28. The physiological measurement system of claim 27, wherein the single protruding convex surface protrudes a height greater than 2 millimeters and less than 3 millimeters.