Method and system for controlling ear stimulation

• US 10,589,105 B2
• Filed: 03/27/2015
• Issued: 03/17/2020
• Est. Priority Date: 03/27/2015
• Status: Active Grant

• Current Assignee: Aurenar Incorporated
• Original Assignee: The Invention Science Fund II, L.L.C. (Intellectual Ventures LLC)
• Inventors: Hyde, Roderick A., Ishikawa, Muriel Y., Kare, Jordin T., Leuthardt, Eric C., Malamud, Mark A., Malaska, Stephen L., Myhrvold, Nathan P., Sweeney, Elizabeth A., Tegreene, Clarence T., Whitmer, Charles, Wood, Jr., Lowell L., Wood, Victoria Y. H.
• Primary Examiner(s): Woodward, Valerie L
• Application Number:
  US14/670,560
• Publication Number:
  US 20160279022A1
• Time in Patent Office: 1,817 Days
• CPC Class Codes: A61H 2201/10 with further special therapeutic means, e.g. electrotherapy, magneto therapy or radiation therapy, chromo therapy, infrared or ultraviolet therapy
• CPC Class Codes: A61H 2201/165 Wearable interfaces
• CPC Class Codes: A61H 2201/501 connected to external computer devices or networks
• CPC Class Codes: A61H 2201/5058 Sensors or detectors
• CPC Class Codes: A61H 2201/5064 Position sensors
• CPC Class Codes: A61H 2201/5082 Temperature sensors
• CPC Class Codes: A61H 2201/5092 Optical sensor
• CPC Class Codes: A61H 2201/5097 wireless
• CPC Class Codes: A61H 2205/027 Ears
• CPC Class Codes: A61H 2230/00 Measuring physical parameters of the user
• CPC Class Codes: A61H 2230/065 used as a control parameter for the apparatus
• CPC Class Codes: A61H 2230/105 used as a control parameter for the apparatus
• CPC Class Codes: A61H 2230/305 used as a control parameter for the apparatus A61H2230/045 takes precedence
• CPC Class Codes: A61H 2230/605 used as a control parameter for the apparatus
• CPC Class Codes: A61H 2230/655 used as a control parameter for the apparatus
• CPC Class Codes: A61H 23/02 with electric or magnetic drive
• CPC Class Codes: A61H 23/0245 with ultrasonic transducers, e.g. piezoelectric
• CPC Class Codes: A61N 1/0456 Specially adapted for transcutaneous electrical nerve stimulation [TENS]
• CPC Class Codes: A61N 1/36031 using physiological parameters for adjustment
• CPC Class Codes: A61N 1/36036 of the outer, middle or inner ear
• CPC Class Codes: A61N 1/37247 : User interfaces, e.g. input or presentation means
• CPC Class Codes: A61N 1/37264 : Changing the program; Upgrading firmware

Abstract

Systems and related methods for controlling delivery of a stimulus to a pinna of a subject with a stimulator worn on the pinna are described. A wearable stimulation device includes a mechanical, electrical, or other type of stimulator secured to a pinna of a subject. A personal computing device in communication with the wearable stimulation device controls delivery of stimuli and other aspects of operation of the device. In some aspects recommendations regarding neural stimuli and other stimuli or experiences to be delivered in association with the neural stimuli are provided via a computing system in communication with the personal computing device or the wearable stimulation device.

Claims

1. A system comprising:

circuitry for receiving a neural activity signal at a personal computing device, the received neural activity signal indicative of a physiological status of a subject, wherein the neural activity signal includes or is computed from at least one of an electroencephalographic signal, an electrooculographic signal, or detected electrical activity of a brain or a nerve of the subject;

circuitry for determining a neural stimulus control signal based at least in part on the received the neural activity signal;

circuitry for outputting the neural stimulus control signal from the personal computing device to a neural stimulation device including an external neural stimulator configured to be carried on a pinna of the subject, wherein the neural stimulus control signal is configured to control delivery of a neural stimulus to the subject by the external neural stimulator, the neural stimulus configured to activate at least one sensory nerve fiber innervating at least a portion of the pinna;

circuitry for receiving a recommendation at the personal computing device, wherein receiving the recommendation at the personal computing device includes at least one of receiving the recommendation via a computing network, receiving the recommendation from a medical care provider, receiving the recommendation from an insurance company, receiving the recommendation from a service provider, receiving the recommendation from an advisor, or receiving the recommendation from a social media source; and

circuitry for presenting the recommendation to the subject, wherein the recommendation is intended to enhance an effect of the neural stimulation received by the subject.

2. A method comprising:

receiving a neural activity signal at a personal computing device, the received neural activity signal indicative of a physiological status of a subject, wherein the neural activity signal includes or is computed from at least one of an electroencephalographic signal, an electrooculographic signal, or detected electrical activity of a brain or nerve of the subject;

determining a neural stimulus control signal based at least in part on the received neural activity signal;

outputting the neural stimulus control signal from the personal computing device to a neural stimulation device including an external neural stimulator configured to be carried on a pinna of the subject, wherein the neural stimulus control signal is configured to control delivery of a neural stimulus to the subject by the external neural stimulator, the neural stimulus configured to activate at least one sensory nerve fiber innervating at least a portion of the pinna;

receiving a recommendation at the personal computing device, wherein receiving the recommendation at the personal computing device includes at least one of receiving the recommendation via a computing network, receiving the recommendation from a medical care provider, receiving the recommendation from an insurance company, receiving the recommendation from a service provider, receiving the recommendation from an advisor, or receiving the recommendation from a social media source; and

presenting the recommendation to the subject, wherein the recommendation is intended to enhance an effect of the neural stimulation received by the subject.

3. The method of claim 2, including providing a report to at least one recipient.

4. The method of claim 3, wherein the at least one recipient includes at least one of the subject, a medical care provider, an insurance company, a service provider, a social media contact of the subject, a caregiver, or a computing system.

5. The method of claim 3, wherein providing the report includes at least one of providing the report via a user interface associated with the neural stimulation device, providing the report via a user interface associated with the personal computing device, providing the report via a computing network, or providing the report in anonymized form.

6. The method of claim 3, wherein the report includes at least one of the neural activity signal, information derived from the neural activity signal, information relating to the mental or emotional state of the subject, information relating to a physiological parameter of the subject, information relating to the neural stimulus control signal, information regarding system settings for at least one of the neural stimulation device and the personal computing device, stored data relating to the neural activity signal, stored data relating to the mental or emotional state of the subject, stored data relating to a physiological parameter of the subject, information relating to a secondary input signal, or information relating to a secondary stimulus.

7. The method of claim 2, including determining a secondary stimulus control signal adapted to control delivery of a secondary stimulus to the subject and delivering the secondary stimulus control signal to a secondary stimulator.

8. The method of claim 7, wherein the secondary stimulus includes at least one of music, an auditory stimulus, a video, a tactile stimulus, a haptic stimulus, an olfactory stimulus, a pharmaceutical, a nutraceutical, or a secondary neural stimulus.

9. The method of claim 7, wherein the secondary stimulus control signal is adapted to control at least one of delivery of a pharmaceutical to the subject by a drug delivery device, prompting of a user via a user interface to administer a pharmaceutical to the subject, operation of a virtual reality system, operation of a game device, delivery of a virtual therapist experience via a computing system, or delivery of an interactive activity via a computing device.

10. The method of claim 2, including receiving a secondary input signal at the personal computing device and determining the neural stimulus control signal based at least in part on the secondary input signal.

11. The method of claim 10, wherein the secondary input signal is representative of at least one of a physiological parameter of the subject, a heart rate, a muscle activity, a blood pressure, perspiration, skin conductivity, respiration, pupil dilation, intestinal activity, piloerection, a motion of the subject, a location of the subject, a microbiome of the subject, a genome of the subject, an environmental parameter, a day length, a light level, a time, a date, a temperature, an ambient noise level, a secondary stimulus to the subject, a user input provided by subject, a user input provided spontaneously by the subject, a user input provided by the subject in response to a prompt or query, or a user input provided by the subject in response to an interactive environment.

12. The method of claim 2, including receiving user input from the subject regarding acceptance or rejection of the recommendation.

13. The method of claim 2, including receiving a patch or update at the personal computing device, the patch or update relating to operation of the neural stimulation device.

14. The method of claim 13, wherein the patch or update is for at least one of software installed on the personal computing device or and software installed on the neural stimulation device.

15. The method of claim 2, including updating a configuration of at least one of the neural stimulation device and the personal computing device, the configuration relating to operation of the neural stimulation device.

16. The method of claim 15, wherein updating the configuration includes updating the configuration based on at least one of historical data, historical data representative of at least one historical value of the neural activity signal, historical data representative of at least one historical value of the neural stimulus control signal, historical data representative of at least one historical value of a secondary input signal, at least one instruction, at least one instruction received from a computing network, at least one instruction received via a user input device, at least one instruction received from a medical care provider, at least one instruction received from an insurance company, at least one instruction received from a service provider, at least one recommendation, at least one recommendation received from an advisor, at least one recommendation received from a computation-based system, at least one recommendation received from a social media source, at least one recommendation based on a preference of at least one social media contact of the subject, at least one recommendation based on a preference of at least one peer of the subject, at least one recommendation based on a preference of at least one role model of the subject, a user input from the subject indicating acceptance of a recommendation by the subject, an input from a caregiver of the subject indicating acceptance of a recommendation by the caregiver, a motion of the subject, a location of the subject, an environmental parameter, or a schedule.

17. The method of claim 2, including presenting information to the subject via a user interface.

18. The method of claim 17, including receiving a credential showing that the subject is an authorized user and presenting the information to the subject via the user interface only following receipt of the credential showing that the subject is an authorized user.

19. The method of claim 18, wherein receiving the credential includes at receiving at least one of a personal identification number, a biometric feature, or a card authentication.

20. The method of claim 17, including changing or discontinuing the presenting of information to the subject via the user interface in response to an input signal.

21. The method of claim 20, wherein the input signal includes at least one of a user input signal, a sensed environmental signal indicative of presence of another person, or a time.

22. The method of claim 17, wherein the user interface includes at least one of an audio output, an alphanumeric display, a graphical display, or a touch screen.

23. The method of claim 17, including customizing for the subject at least one of the information presented via the user interface or the formatting of the information presented via the user interface.

24. The method of claim 17, wherein the user interface includes a graphical display, and wherein presenting the information to the subject via the user interface includes at least one of presenting the information to the subject in a graphical format that mimics the graphical format of a music player, presenting the information to the subject in a graphical format that mimics the graphical format of a mobile phone, or presenting the information to the subject in a graphical format that mimics the graphical format of a familiar user interface.

25. The method of claim 2, including modulating the neural stimulus control signal to discontinue production of the neural stimulus in response to an override signal.

26. The method of claim 25, including at least one of receiving the override signal via a user input device, receiving the override signal from a sensor responsive to sensing a presence of a person other than the subject in the vicinity of the subject, receiving the override signal from a physiological sensor indicating of an unsafe condition, or receiving the override signal from a sensor responsive to sensing that the external neural stimulator is not properly positioned on the pinna of the subject.

27. The method of claim 2, including receiving a position signal indicative of the position of the external neural stimulator with respect to the pinna of the subject.

28. The method of claim 27, including delivering a notification to the subject indicating that the external neural stimulator should be repositioned, wherein delivering the notification to the subject includes at least one of delivering the notification via a graphical display of the personal computing device, delivering an auditory alert, delivering a visual alert, delivering a voice message, delivering the notification via an audio output of the personal computing device, delivering the notification via an audio output of the neural stimulation device, storing information indicating that stimulator is improperly positioned in a data storage location in the personal computing device, or storing information indicating that stimulator is improperly positioned in a data storage location in the neural stimulation device.

29. The method of claim 2, including outputting an audio output signal via an audio output of the personal computing device, wherein the audio output signal is configured for driving delivery of sound to the ear of the subject via a sound source.

30. The method of claim 29, including delivering the audio output signal to at least one of a sound source on the neural stimulation device or a sound source distinct from the neural stimulation device.

31. The method of claim 29, including at least one of retrieving an audio signal from a data storage location on the personal computing device and outputting the audio output signal based on the audio signal retrieved from the data storage location on the personal computing device, or receiving an audio input signal from a telecommunication network and outputting the audio output signal based on the audio input signal.

32. The method of claim 29, including at least one of outputting the audio output signal simultaneously with the neural stimulus control signal, switching between outputting the audio output signal and outputting the neural stimulus control signal, giving higher priority to outputting of the neural stimulus control signal than to outputting of the audio output signal, giving higher priority to outputting of the audio output signal than to outputting of the neural stimulus control signal, automatically discontinuing outputting of the neural stimulus control signal and starting outputting of the audio output signal in response to receipt of an audio input signal, or automatically declining an audio input signal if the neural stimulus is currently being delivered.

33. The method of claim 2, including receiving the neural activity signal via at least one of a headphone jack, a data input, a wireless receiver, a body area network, a local area network, or a wide area network.

34. The method of claim 2, wherein determining the neural stimulus control signal includes determining at least one of a neural stimulus amplitude, a neural stimulus frequency, a neural stimulus duration, a neural stimulus waveform, or a stimulation pattern.

35. The method of claim 2, wherein the neural stimulus control signal is configured to cause delivery of at least one of a continuous neural stimulus, an intermittent neural stimulus, a time-varying neural stimulus, a pulsed neural stimulus, or a neural stimulus selected from a plurality of pre-programmed stimulation patterns.

36. The method of claim 2, including at least one of storing data on the personal computing device representing the received neural activity signal, storing data on the personal computing device representing the determined neural stimulus control signal, predicting future neural activity signal based on a previous neural activity signal, determining a neural stimulus based on a previous neural activity signal, or determining a secondary stimulus based on the neural activity signal.

37. The method of claim 2, including at least one of receiving the neural activity signal via a secure connection or outputting the neural stimulus control signal via a secure connection.

38. The method of claim 2, wherein the recommendation relates to at least one of a configuration of the neural stimulus control signal, a secondary stimulus, a consumer product, a service, a user experience, a user activity, or an organization.

39. A computer program product comprising:

a non-transitory signal-bearing medium bearing

one or more instructions for receiving a neural activity signal at a personal computing device, the received neural activity signal indicative of a physiological status of a subject, wherein the received neural activity signal includes or is computed from at least one of an electroencephalographic signal, an electrooculographic signal, or detected electrical activity of a brain or nerve of the subject;

one or more instructions for determining a neural stimulus control signal based at least in part on the received neural activity signal;

one or more instructions for outputting the neural stimulus control signal from the personal computing device to a neural stimulation device including an external neural stimulator configured to be carried on a pinna of the subject, wherein the neural stimulus control signal is configured to control delivery of a neural stimulus to the subject by the external neural stimulator, the neural stimulus configured to activate at least one sensory nerve fiber innervating at least a portion of the pinna; and

one or more instructions for presenting a recommendation to the subject wherein the recommendation is based on at least one of at least one preference of at least one social media contact of the subject, at least one preference of at least one peer of the subject, or at least one preference of at least one role model of the subject.

40. The computer program product of claim 39, wherein the non-transitory signal bearing medium bears one or more instructions for receiving the neural activity signal via at least one of a headphone jack, a data input, a wireless receiver, a body area network, a local area network, or a wide area network.

41. A method comprising:

receiving a neural activity signal at a personal computing device, the received neural activity signal indicative of a physiological status of a subject;

determining a neural stimulus control signal based at least in part on the received neural activity signal;

outputting the neural stimulus control signal from the personal computing device to a neural stimulation device including an external neural stimulator configured to be carried on a pinna of the subject, wherein the neural stimulus control signal is configured to control delivery of a neural stimulus to the subject by the external neural stimulator, the neural stimulus configured to activate at least one sensory nerve fiber innervating at least a portion of the pinna; and

presenting a recommendation to the subject;

wherein the recommendation is based on at least one of at least one preference of at least one social media contact of the subject, at least one preference of at least one peer of the subject, or at least one preference of at least one role model of the subject.