System and method for determining vital sign information of a subject

• US 10,602,962 B2
• Filed: 10/23/2014
• Issued: 03/31/2020
• Est. Priority Date: 11/01/2013
• Status: Active Grant

• Current Assignee: Koninklijke Philips N.V.
• Original Assignee: Koninklijke Philips N.V.
• Inventors: Dubielczyk, Alexander, Epping, Christian Michael, Neumann, Rolf
• Primary Examiner(s): Pehlke, Carolyn A
• Assistant Examiner(s): Saboktakin, Marjan
• Application Number:
  US14/521,944
• Publication Number:
  US 20150126872A1
• Time in Patent Office: 1,986 Days
• CPC Class Codes: A61B 2090/3945 Active visible markers, e.g. light emitting diodes
• CPC Class Codes: A61B 2090/3979 infrared
• CPC Class Codes: A61B 2090/3991 having specific anchoring means to fixate the marker to the tissue, e.g. hooks
• CPC Class Codes: A61B 5/0075 by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy A61B5/0071 takes precedence
• CPC Class Codes: A61B 5/0077 Devices for viewing the surface of the body, e.g. camera, magnifying lens
• CPC Class Codes: A61B 5/087 Measuring breath flow
• CPC Class Codes: A61B 5/0873 using optical means
• CPC Class Codes: A61B 5/0876 using means deflected by the fluid stream, e.g. flaps
• CPC Class Codes: A61B 5/091 Measuring volume of inspired or expired gases, e.g. to determine lung capacity
• CPC Class Codes: A61B 5/1114 Tracking parts of the body
• CPC Class Codes: A61B 5/1127 using markers
• CPC Class Codes: A61B 5/6819 Nose
• CPC Class Codes: A61B 5/682 Mouth, e.g., oral cavity; tongue; Lips; Teeth
• CPC Class Codes: A61B 5/6833 Adhesive patches
• CPC Class Codes: A61B 5/7278 Artificial waveform generation or derivation, e.g. synthesising signals from measured signals A61B5/327 takes precedence
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers

Abstract

Vital sign information of a subject is determined using a marker for application to the subject. The marker is configured to change an optical property due to a mechanical manipulation of the marker caused by a physiological process of the subject. The change in the optical property is detected and analyzed to determine vital sign information of the subject.

Claims

1. A system for determining breathing information of a subject comprising

a marker configured for application to the subject, the marker including a patch with flexible filaments protruding from a surface, the filaments being configured to flex in response to air flow during inhalation and exhalation, the filaments having at least one of a color and brightness gradient along the filaments from top to bottom such that at least one of the color and brightness of the patch changes as the filaments flex,

a camera configured to detect the changes in at least one of the color and brightness of the patch in response to the air flow, and

a computer configured to identify the marker in a video image from the camera and determine the breathing information of the subject from the detected changes in at least one of the color and brightness of the patch.

2. The system according to claim 1, wherein the determined breathing information includes whether the subject is inhaling or exhaling.

3. The system according to claim 2, wherein the computer is further configured to determine a respiration rate of the subject and further including:

a display device configured to display the respiration rate.

4. The system according to claim 1, wherein the filaments include:

a first surface having a first color gradient and a second surface having a second color gradient, the first color gradient being different from the second color gradient.

5. The system according to claim 2, wherein the change in at least one of the color and brightness gradient is indicative of breathing strength over time and wherein the computer is further configured to:

integrate the change over time to derive information about the tidal volume.

6. The system according to claim 1, wherein the patch includes a bar code or a QR code with a patient identifier detectable by the camera.

7. The system according to claim 1, wherein the marker comprises one or more optical features for detection by the camera, the one or more optical features being selected from a group of features comprising:

an optical feature for tracking the marker, an optical feature for reference, an optical feature for measurement at night, and an optical feature for information coding.

8. The system according to claim 1, wherein the filaments have a color gradient from the top to the bottom.

9. A method for determining vital sign information of a subject comprising the steps of:

applying a patch with protruding flexible filaments adjacent a nasal or oral region of the subject, the flexible filaments being configured to flex and have a first color property due to a mechanical manipulation during inhalation and a second color property during exhalation to a subject, the second color property being different from the first color property;

detecting light reflected from the flexible filaments with a camera; and

determining respiration information of the subject from the detected light.

10. The method according to claim 9, wherein the flexible filaments have first and second colors on first and second sides, such that patient inhalation causes the camera to see the first color and patient exhalation causes the camera to see the second color;

and

determining the respiration information includes;

determining a respiration rate.

11. The method according to claim 9, wherein the marker includes a bar or QR code.

12. A marker for use in a system for determining respiratory information, the marker including:

a patch configured to be applied to the subject adjacent nostrils of a subject and including filaments protruding from the surface, the filaments being configured to flex differently in response to air flow during inhalation and exhalation, wherein the filaments having a first color on a first surface and a second color on a second surface, the first color being different from the second color, the filaments being configured such that when flexing in response to inhalation, the patch shows the first color and when flexing in response to exhalation, the patch shows the second color.

13. The marker according to claim 12, wherein the filaments flex one way during inhalation and an opposite way during exhalation.

14. The marker according to claim 13, wherein the filaments have color gradients from top to bottom to provide an indication of breathing strength.

15. The marker according to claim 13, wherein the patch includes a bar or QR code carrying information about the patient.

16. The marker according to claim 13, further including a second patch configured to be applied to the subject in a reference location insensitive to exhalation or inhalation.

17. A marker for use in a system for determining respiratory information, comprising:

a lipstick configured to be applied to the lips of a subject, the lipstick being configured to have a first color property when the subject inhales and a second color property when the subject exhales, the second color property being different from the first color property.

18. A method of determining respiratory information of a patient, the method comprising:

applying a colorimetric lipstick to lips of the patient, the colorimetric lipstick being configured to have different optical properties during inhalation than during exhalation;

with a camera, detecting light reflected from the colorimetric lipstick and generating an output signal indicative of changing of the optical properties as the patient breathes; and

converting the output signal into the respiratory information.

19. The method according to claim 18, wherein the respiratory information includes respiration motion.