System and methods for processing analyte sensor data for sensor calibration

  • US 10,610,136 B2
  • Filed: 06/28/2019
  • Issued: 04/07/2020
  • Est. Priority Date: 03/10/2005
  • Status: Active Grant
First Claim
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1. A method for calibrating data from a glucose sensor, wherein the glucose sensor is configured for transcutaneous implantation in a host while operably connected to sensor electronics, and wherein the glucose sensor comprises a membrane system, the method comprising:

  • receiving information associated with a priori sensitivity for the glucose sensor prior to implantation of the glucose sensor in the host, wherein the information associated with the a priori sensitivity is derived at least in part from an analysis of glucose sensor sensitivities collected from a set of glucose sensors that are representative of the glucose sensor with respect to a predictive relationship between in vivo and in vitro sensitivities;

    receiving sensor data from the glucose sensor by the sensor electronics after the glucose sensor is implanted in the host, wherein the sensor data is representative of a glucose concentration in the host; and

    calibrating, using a processor operably connected to the sensor electronics, the sensor data received from the glucose sensor, wherein the calibrating is performed based at least in part on the received information associated with the a priori sensitivity without reliance on reference glucose values obtained from a self-monitoring blood glucose test after implantation of the glucose sensor in the host.

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