Systems, devices, and methods for setting cardiac pacing pulse parameters for a cardiac pacing device

• US 10,632,313 B2
• Filed: 11/06/2017
• Issued: 04/28/2020
• Est. Priority Date: 11/09/2016
• Status: Active Grant

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Juffer, Lance Eric, Linder, William J., Balczewski, Ron A., Maile, Keith R.
• Primary Examiner(s): Dietrich, Joseph M
• Application Number:
  US15/804,699
• Publication Number:
  US 20180126174A1
• Time in Patent Office: 904 Days
• CPC Class Codes: A61N 1/3708 for power depletion
• CPC Class Codes: A61N 1/371 Capture, i.e. successful stimulation
• CPC Class Codes: A61N 1/3712 Auto-capture, i.e. automatic adjustment of the stimulation threshold
• CPC Class Codes: A61N 1/37247 User interfaces, e.g. input or presentation means
• CPC Class Codes: A61N 1/37512 Pacemakers
• CPC Class Codes: A61N 1/3756 Casings with electrodes thereon, e.g. leadless stimulators
• CPC Class Codes: A61N 1/378 Electrical supply

Abstract

Systems, devices, and methods for pacing a heart of a patient are disclosed. A device may include a leadless cardiac pacemaker (LCP) that includes a power supply, a pair of electrodes, and a controller operably connected to the electrodes and the power supply. The controller may identify a capture threshold by setting a pace amplitude at a power supply voltage of the power supply and deliver pacing stimulation pulses with different pulse widths to identify the capture threshold. The LCP may then deliver pacing stimulation pulses based, at least in part, on a pulse amplitude and pulse width associated with the capture threshold, and also adding a capture margin. In some cases, the pulse amplitude may change over time and the LCP may adjust a pulse width along a strength-duration curve to account for the pulse amplitude change and maintain a capture threshold and capture margin.

Claims

1. A leadless cardiac pacemaker (LCP) for delivering pacing pulses to a heart of a patient, the LCP comprising:

a power supply for providing a power supply voltage;

a pair of electrodes for delivering pacing pulses to the heart of the patient;

a controller operably connected to the pair of electrodes and the power supply, the controller configured to;

identify a capture threshold by;

setting a pace amplitude to the power supply voltage;

delivering via the pair of electrodes a plurality of pacing pulses having the pace amplitude with different pulse widths to identity a capture pulse width that corresponds to the capture threshold of the heart;

deliver via the pair of electrodes a plurality of pacing pulses having the pace amplitude and a pacing pulse width that is greater than the capture pulse width by a pulse width margin.

2. The LCP of claim 1, wherein the power supply comprises a battery, and the power supply voltage comprises a battery voltage provided by the battery.

3. The LCP of claim 2, wherein the battery voltage, and thus the pace amplitude, decays over time.

4. The LCP of claim 3, wherein the controller is configured to repeatedly identify the capture threshold.

5. The LCP of claim 1, wherein the controller stores data representing one or more strength-duration curves, and the controller is configured to identify a capture threshold strength-duration curve based at least in part on the pace amplitude and the capture pulse width, and the controller is further configured to identify the pulse width margin by referencing a different one of the strength-duration curves and the pace amplitude.

6. The LCP of claim 5, wherein if the power supply voltage changes, and thus the pace amplitude changes, the controller is configured to automatically adjust the pacing pulse width based at least in part on the different one of the strength-duration curves and the changed pace amplitude, without having to update the capture threshold by delivering via the pair of electrodes a plurality of pacing pulses having the changed pace amplitude and different pulse widths.

7. The LCP of claim 1, wherein the controller is further configured to receive a user selectable power efficiency value, and wherein the pulse width margin is based at least in part on the user selectable power efficiency value.

8. A leadless cardiac pacemaker (LCP) for delivering pacing pulses to a heart of a patient, the LCP comprising:

a pair of electrodes for delivering pacing pulses to the heart of the patient;

a controller operably connected to the pair of electrodes, the controller configured to;

identify a capture threshold by delivering via the pair of electrodes a plurality of pacing pulses while varying a first pacing pulse parameter value while leaving a second pacing pulse parameter value fixed in order to identity a capture value for the first pacing pulse parameter; and

deliver via the pair of electrodes a plurality of pacing pulses that each have the first pacing pulse parameter value at the capture value and the second pacing pulse parameter value at a capture margin above the fixed second pacing pulse parameter value.

9. The LCP of claim 8, wherein the first pacing pulse parameter is pulse width and the second pacing pulse parameter is pulse amplitude.

10. The LCP of claim 9, further comprising a battery that provides a battery voltage, and wherein the fixed second pacing pulse parameter value is a predetermined fraction of the battery voltage.

11. The LCP of claim 10, wherein the second pacing pulse parameter value at the capture margin above the fixed second pacing pulse parameter value corresponds to the battery voltage.

12. The LCP of claim 8, wherein the first pacing pulse parameter is pulse amplitude and the second pacing pulse parameter is pulse width.

13. The LCP of claim 8, wherein the controller stores data representing one or more strength-duration curves, and the controller is configured to identify the capture margin based at least in part on one or more of the strength-duration curves.

14. A leadless cardiac pacemaker (LCP) for delivering pacing pulses to a heart of a patient, the LCP comprising:

a pair of electrodes for delivering pacing pulses to the heart of the patient;

a controller operably connected to the pair of electrodes, the controller configured to;

receive a user selectable power efficiency value from a remote device;

identify a pulse width and pulse amplitude combination that corresponds to a capture threshold;

apply a capture margin to one or more of the pulse width and pulse amplitude resulting in a pacing pulse width and a pacing pulse amplitude, wherein the capture margin is based at least in part on the user selectable power efficiency value; and

deliver pacing pulses using the pacing pulse width and the pacing pulse amplitude.

15. The LCP of claim 14, wherein the controller is configured to store data representing one or more strength-duration curves, and wherein the controller is configured to identify the capture margin by indexing the user selectable power efficiency value into the data representing one or more strength-duration curves.

16. The LCP of claim 15, wherein the controller is configured to receive the data representing one or more strength-duration curves from the remote device.

17. The LCP of claim 14, wherein the remote device comprises a user interface including a display, wherein a user can use the user interface to select the user selectable power efficiency value.

18. The LCP of claim 17, wherein the remote device displays a slider on the display that allows the user select the user selectable power efficiency value from a range of allowable user selectable power efficiency values.

19. The LCP of claim 17, wherein the remote device displays a dynamic indicator of an expected life time of the LCP based, at least in part, on the user selectable power efficiency value.

20. The LCP of claim 14, further comprising a battery for providing a battery voltage, and wherein the pacing pulse amplitude is set to the battery voltage.