Devices with reduced sweat volumes between sensors and sweat glands

• US 10,639,015 B2
• Filed: 05/28/2015
• Issued: 05/05/2020
• Est. Priority Date: 05/28/2014
• Status: Active Grant

• Current Assignee: University of Cincinnati
• Original Assignee: University of Cincinnati
• Inventors: Heikenfeld, Jason C.
• Primary Examiner(s): Messersmith, Eric J
• Application Number:
  US15/314,418
• Publication Number:
  US 20170095233A1
• Time in Patent Office: 1,804 Days
• CPC Class Codes: A61B 10/0064 for taking sweat or sebum samples measuring sweat production A61B5/4266
• CPC Class Codes: A61B 2560/0412 Low-profile patch shaped housings
• CPC Class Codes: A61B 5/0531 Measuring skin impedance
• CPC Class Codes: A61B 5/0537 Measuring body composition by impedance, e.g. tissue hydration or fat content
• CPC Class Codes: A61B 5/14521 using means for promoting sweat production, e.g. heating the skin measuring sweat secretion A61B5/4266
• CPC Class Codes: A61B 5/4266 sweat secretion
• CPC Class Codes: A61B 5/6833 Adhesive patches

Abstract

A sweat sensor device (400c) for sensing sweat on the skin (12) includes one or more sweat sensors (420) and a volume-reducing component that provides a volume-reduced pathway (480) for sweat between the one or more sweat sensors (420) and sweat glands in said skin (12) when the device (400c) is positioned on said skin (12). The volume-reducing component may include a volume-reducing material (470) and a pressure-permeated component (460), a sweat dissolvable material (490), a mechanically compliant material (570) for conforming to the skin (12), an adhesive with a vertically anisotropic sweat pathway, and microcapsules (1385) including a barrier material. The presence of a volume-reducing component reduces the sweat volume and decreases the sampling interval.

Claims

1. A sweat sensor device for sensing sweat on the skin comprising:

one or more sweat sensors; and

a volume-reducing component that provides a dominantly vertical pathway for sweat between and sweat glands and the one or more sweat sensors when said device is positioned on said skin,

wherein said volume-reducing component is selected from the group consisting of a volume-reducing material and a pressure-permeated component, a sweat dissolvable material, a mechanically compliant material for conforming to a surface of said skin, an adhesive with a vertically anisotropic sweat pathway, the adhesive preventing horizontal movement of sweat, microcapsules including a barrier material, and combinations thereof.

2. The device of claim 1, wherein the volume-reducing component includes a material configured to dissolve on contact with sweat so that sweat creates one or more vertical pathways from the skin through the material, and a pressure-permeated component.

3. The device of claim 1, wherein the volume-reducing component includes a plurality of pathways oriented vertically, and wherein the pathways are configured to inhibit horizontal movement of sweat.

4. The device of claim 3, wherein the plurality of enclosed volumes is a microfluidically connected network of closed-cell sweat volumes.

5. The device of claim 1, wherein the volume-reducing component includes a curable adhesive.

6. The device of claim 1, wherein the volume-reducing component includes a sweat dissolvable material that is configured to dissolve on contact with sweat so that sweat creates one or more vertical pathways from the skin through the material.

7. The device of claim 6, wherein the sweat dissolvable material is microporous.

8. The device of claim 6, wherein the sweat dissolvable material includes a sweat-wetting promoting feature.

9. The device of claim 1, wherein the volume-reducing component includes the mechanically compliant material for conforming to a surface of said skin, the mechanically compliant material including a plurality of beads.

10. The device of claim 9, wherein at least a portion of the beads are hydrophilic.

11. The device of claim 9, wherein at least a portion of the beads are hydrophobic.

12. The device of claim 9, wherein at least a portion of the beads are oleoscopic.

13. The device of claim 9, wherein at least a portion of the beads include a transferable sweat impermeable coating.

14. The device of claim 9, wherein at least a portion of the beads include an adhesive coating.

15. The device of claim 9, wherein at least a portion of the beads have at least one magnetic property.

16. The device of claim 1, wherein the volume-reducing component includes an adhesive with a vertically anisotropic sweat pathway.

17. The device of claim 16, wherein said adhesive includes a dominantly vertical porous network.

18. The device of claim 1, wherein the volume-reducing component includes microcapsules including a barrier material and, when the device is applied to the skin, the microcapsules release the barrier material to form a barrier on said skin.

19. The device of claim 1, including a sweat stimulating component.

20. The device of claim 19, wherein said sweat stimulation component includes a second volume-reduced pathway between sweat stimulating component and sweat glands when said device is positioned on said skin;

and

wherein said volume-reducing pathway is defined by one or more features from the group consisting of a volume-reducing material and a pressure-permeated component, a sweat dissolvable material, a mechanically compliant material for conforming to a surface of said skin, an adhesive with a vertically anisotropic sweat pathway, microcapsules including a barrier material, beads, a plurality of horizontally enclosed volumes, and combinations thereof.

21. The device of claim 1, wherein said volume reducing component provides a volume-reduced pathway for sweat between said one or more sweat sensors and sweat glands when said device is positioned on said skin, said volume-reduced pathway including a predetermined pathway for sweat across said sensors;

and

wherein one or more sensors has a sampling interval when sensing sweat and said volume reduced pathway decreases the sampling interval for said one or more sensors.

22. The device of claim 21, wherein a flow of said sweat from said skin is centered in said one or more sweat sensors.

23. A sweat sensor device for sensing sweat on the skin comprising:

one or more sweat sensors; and

a volume-reducing component that provides a volume-reduced pathway for sweat between the one or more sweat sensors and sweat glands when said device is positioned on said skin,

wherein said volume-reducing component includes a plurality of enclosed volumes.

24. The device of claim 23, wherein said plurality of enclosed volumes is a microfluidically connected network of closed-cell sweat volumes.