Pharmaceutical spray composition comprising a vitamind D analogue and a corticosteroid

  • US 10,682,364 B2
  • Filed: 08/28/2019
  • Issued: 06/16/2020
  • Est. Priority Date: 06/11/2010
  • Status: Active Grant
First Claim
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1. A sprayable, substantially anhydrous topical composition comprisingcalcipotriol or calcipotriol monohydrate,betamethasone dipropionate,a pharmaceutically acceptable propellant, present in amount between 45-95% w/w of the total composition,a pharmaceutically acceptable lipid carrier, present in an amount between 5-55% w/w of the total composition, anda pharmaceutically acceptable antioxidant,wherein the composition does not include propylene glycol, andwherein no more than 10% by weight of the calcipotriol or calcipotriol monohydrate has degraded after storage of the composition for 3 months at about 40°

  • C.

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