Wearable pulse pressure wave sensing device

• US 10,694,960 B2
• Filed: 09/29/2014
• Issued: 06/30/2020
• Est. Priority Date: 09/29/2014
• Status: Active Grant

• Current Assignee: Microsoft Technology Licensing LLC (Microsoft Corporation)
• Original Assignee: Microsoft Technology Licensing LLC (Microsoft Corporation)
• Inventors: Saponas, T. Scott, Morris, Dan, Villar, Nicolas, Patel, Shwetak, Smith, Greg R., Tan, Desney, Vardoulis, Orestis, Gupta, Sidhant
• Primary Examiner(s): Pehlke, Carolyn A
• Application Number:
  US14/500,459
• Publication Number:
  US 20160089042A1
• Time in Patent Office: 2,101 Days
• CPC Class Codes: A61B 2562/0247 Pressure sensors
• CPC Class Codes: A61B 2562/046 in a matrix array
• CPC Class Codes: A61B 5/0059 using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: A61B 5/02405 Determining heart rate variability
• CPC Class Codes: A61B 5/02438 with portable devices, e.g. worn by the patient
• CPC Class Codes: A61B 5/1079 using optical or photographic means
• CPC Class Codes: A61B 5/681 Wristwatch-type devices
• CPC Class Codes: A61B 5/721 using a separate sensor to detect motion or using motion information derived from signals other than the physiological signal to be measured
• CPC Class Codes: A61B 8/085 for locating body or organic structures, e.g. tumours, calculi, blood vessels, nodules

Abstract

Wearable pulse pressure wave sensing devices are presented that generally provide a non-intrusive way to measure a pulse pressure wave travelling through an artery using a wearable device. In one implementation, the device includes an array of pressure sensors disposed on a mounting structure which is attachable to a user on an area proximate to an underlying artery. Each of the pressure sensors is capable of being mechanically coupled to the skin of the user proximate to the underlying artery. In addition, there are one or more arterial location sensors disposed on the mounting structure which identify a location on the user'"'"'s skin likely overlying the artery. A pulse pressure wave is then measured using the pressure sensor of the array closest to the identified location.

Claims

1. A wearable pulse pressure wave sensing device, comprising:

a mounting structure configured to be attachable to a user'"'"'s skin on an area proximate to an underlying artery;

an array of pressure sensors disposed on said mounting structure, each pressure sensor of the array being configured to measure a pulse pressure wave traveling through the underlying artery;

one or more image-based arterial location sensors disposed on the mounting structure and configured to identify a location on the user'"'"'s skin likely overlying the underlying artery, each of the one or more image-based arterial location sensors being calibrated so that pixels in images captured by the image-based arterial location sensor are mapped to locations relative to each pressure sensor of the array of pressure sensors;

one or more processors; and

one or more storage devices holding instructions executable by the one or more processors to;

capture, via the one or more image-based arterial location sensors, one or more images of the user'"'"'s skin,

analyze the one or more captured images to visually identify a location on the user'"'"'s skin likely overlying the underlying artery,

select a single pressure sensor from the array of pressure sensors that is mapped to the identified location in the one or more captured images, and

measure, via the single selected pressure sensor, the pulse pressure wave.

2. The device of claim 1, wherein the pressure sensors in the array of pressure sensors are coated with a skin-sensor interface material having a shape which protrudes from the mounting structure so as to contact the skin of the user whenever the wearable pulse pressure wave sensing device is worn by the user.

3. The device of claim 2, wherein one or more of the coated pressure sensors comprise a single skin interfacing and arterial pressure wave movement transmission layer that is made of a material that lays on the skin of the user and transmits arterial pressure wave movement.

4. The device of claim 2, wherein the pressure sensors of the array of pressure sensors are coated with the skin-sensor interface material.

5. The device of claim 1, wherein the one or more image-based arterial location sensors identify a location on the user'"'"'s skin in the area proximate to the underlying artery which exhibits the greatest displacement of the user'"'"'s skin as said location likely overlying said artery.

6. The device of claim 5, wherein the one or more image-based arterial location sensors comprise reflected optical sensors or ultrasonic sensors.

7. The device of claim 1, further comprising one or more non-arterial motion sensors disposed on said mounting structure which measure the motion of the user'"'"'s body in the area proximate to the underlying artery that is not caused by motion of the artery, and wherein a signal or signals output from the one or more non-arterial motion sensors representing the non-arterial motion of the user'"'"'s body in the area proximate to the underlying artery are employed to remove a portion of a signal output from the pressure sensor of the array of pressure sensors identified as being most closely overlying the likely location of the artery attributable to non-arterial motion.

8. The device of claim 7, wherein the one or more non-arterial motion sensors comprise an accelerometer or gyroscope, or both.

9. The device of claim 1, wherein the mounting structure comprises a band which is either adhered to the area proximate to the underlying artery, or wrapped around and tightened against said area.

10. The device of claim 9, wherein said area proximate to an underlying artery is the user'"'"'s wrist.

11. The device of claim 1, wherein the one or more storage devices holding instructions executable by the one or more processors to turn off the pressure sensors of the array other than the selected single pressure sensor while the single selected pressure sensor is used to measure the pulse pressure wave.

12. The wearable pulse pressure wave sensing device of claim 1, wherein the one or more image-based location sensors are configured to measure skin displacement of the area on the user'"'"'s skin, and wherein the location on the user'"'"'s skin likely overlying the underlying artery is identified based on measurements of skin displacement of the area of the user'"'"'s skin via the one or more image-based arterial location sensors.

13. A computer-implemented process for measuring a pulse pressure wave travelling through an artery of a user, comprising the actions of:

using a computing device to perform the following process actions;

capturing one or more images of the user'"'"'s skin using one or more image-based arterial location sensors, wherein each image-based arterial location sensor is calibrated so that pixels in the one or more images captured by the one or more image-based arterial location sensors are mapped to locations relative to each of a plurality of pressure sensors of an array of pressure sensors;

analyzing the one or more captured images to visually identify a location on the skin of the user in an area proximate to the underlying artery which exhibits the greatest displacement of the user'"'"'s skin when a pulse pressure wave passes through the underlying artery in said area;

determining which single pressure sensor of the array of pressure sensors is mapped to the identified location on the user'"'"'s skin;

selecting the single pressure sensor determined to be mapped to the identified location; and

measuring another pulse pressure wave travelling through the underlying artery using the selected single pressure sensor.

14. The process of claim 13, further comprising turning off the pressure sensors of the array other than the selected single pressure sensor while the single selected pressure sensor is used to measure the pulse pressure wave.

15. A system for analyzing a pressure wave travelling through an artery of a user, comprising:

a band which is either adhered to an area proximate to an underlying artery of the user'"'"'s body, or wrapped around and tightened against said area;

an array of pressure sensors disposed on said band, each pressure sensor of the array being configured to measure a pulse pressure wave traveling through the underlying artery;

one or more image-based arterial location sensors disposed on said band and configured to identify a location on the user'"'"'s skin likely overlying the underlying artery;

an array of pressure sensors disposed on said band, each of the one or more image-based arterial location sensors being calibrated so that pixels in images captured by the image-based arterial location sensor are mapped to locations relative to each pressure sensor of the array of pressure sensors; and

a computing device which executes program modules of a computer program, the computing device being directed by the program modules of the computer program to;

capture, via the one or more image-based arterial location sensors, one or more images of the user'"'"'s skin,

analyze the one or more captured images to visually identify a location on the user'"'"'s skin in the area proximate to the underlying artery which exhibits the greatest displacement of the user'"'"'s skin when a pulse pressure wave passes through the underlying artery using the received signals output from the one or more arterial location sensors,

determine which single pressure sensor of the array of pressure sensors is mapped to the identified location on the user'"'"'s skin in the one or more captured images,

select the single pressure sensor determined to be mapped to the identified location,

receive a signal output from just the selected single pressure sensor when a pulse pressure wave is traveling through the underlying artery, and

analyze the received signal to measure the pulse pressure wave.

16. The system of claim 15, wherein the program module for analyzing the received signal comprises sub-modules for determining at least one of:

a heart rate of the user;

or

variations in the user'"'"'s heart rate over time;

or

the user'"'"'s augmentation index which is computed using a pulse waveform extracted from said received signal;

or

a time of arrival of the pulse pressure wave which is used in conjunction with other data to calculate pulse transit time or pulse wave velocity or both.

17. The system of claim 15, wherein the computing device is directed by the program modules of the computer program to turn off the pressure sensors of the array other than the selected single pressure sensor while the single selected pressure sensor is used to measure the pulse pressure wave.