Methods of treating and preventing graft versus host disease

  • US 10,695,350 B2
  • Filed: 09/25/2019
  • Issued: 06/30/2020
  • Est. Priority Date: 10/25/2013
  • Status: Active Grant
First Claim
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1. A method for achieving a complete resolution of symptoms of chronic graft versus host disease (GVHD) in an adult patient having chronic GVHD refractory to systemic therapy comprising orally administering 420 mg of ibrutinib once per day to the adult patient having chronic GVHD refractory to systemic therapy, thereby achieving complete resolution of the symptoms of refractory chronic GVHD in the adult patient, and discontinuing administering ibrutinib when the adult patient no longer requires therapy for the chronic GVHD.

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