Method and system for monitoring and treating hypoglycemia

• US 10,772,556 B2
• Filed: 03/18/2015
• Issued: 09/15/2020
• Est. Priority Date: 11/05/2014
• Status: Active Grant

• Current Assignee: Claudio Afonso Ambrosio
• Original Assignee: Claudio Afonso Ambrosio
• Inventors: Ambrosio, Claudio Afonso
• Primary Examiner(s): Natnithithadha, Navin
• Assistant Examiner(s): Shostak, Andrey
• Application Number:
  US14/662,011
• Publication Number:
  US 20160270722A1
• Time in Patent Office: 2,008 Days
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61B 5/746 Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms alarms per se G08B
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 40/67 for remote operation

Abstract

A system and method for monitoring a patient'"'"'s blood glucose levels and communicating such levels to a patient care network is provided. More particularly, a monitor for measuring blood glucose levels may be adapted to alert the patient and preselected members of the patient care network in the event that the patient'"'"'s blood glucose levels fall below a threshold amount. The monitor may be further adapted to communicate with means for automatically delivering glucose into a patient'"'"'s body and means for delivering insulin into the patient'"'"'s body, each means operating alone or in combination. Such a system and method may have applications in preventing symptomatic hypoglycemic episodes and providing diagnostic aid to medical professionals.

Claims

1. A system for monitoring and treating hypoglycemia in a patient, the system comprising:

a glucose pump configured to deliver therapeutic doses of glucose into the patient;

an insulin pump configured to deliver therapeutic doses of insulin into the patient;

a patient care network, facilitated by a web-based software application that facilitates interaction amongst a limited group of members defined by the patient care network with one another, wherein the limited group of members of the patient care network includes the patient, at least one medical professional associated with at least one first electronic device, and at least one emergency contact associated with at least one second electronic device, wherein each of the at least one first electronic device and the at least one second electronic device are configured to receive and display at least one glucose reading; and

a monitor communicatively coupled to the glucose pump, the insulin pump, the at least one first electronic device and the at least one second electronic device via a communication network, wherein the monitor is configured to;

measure blood glucose levels of the patient;

continuously or periodically communicate the measured blood glucose levels to one or more of the at least one first electronic device and the at least one second electronic device of the patient care network via the communication network;

determine whether one or more of the measured blood glucose levels are below one or more threshold amounts; and

prompt treatment to correct low blood glucose levels of the patient in response to at least one of the measured blood glucose levels being below at least one of the one or more threshold amounts, wherein prompting treatment includes;

alerting the patient via an alarm of the monitor in response to one of the measured blood glucose levels being below a first threshold amount;

communicating an alert to one or more of the at least one first electronic device and the at least one second electronic device via the communication network in response to one of the measured blood glucose levels being below a second threshold amount that is lower than the first threshold amount;

communicating instructions to the insulin pump to stop delivery of insulin into the patient via the communication network in response to one of the measured blood glucose levels being below a third threshold amount; and

communicating instructions to the glucose pump to begin delivery of glucose into the patient via the communication network in response to one of the measured blood glucose levels being below a fourth threshold amount that is lower than the third threshold amount, wherein;

the first threshold amount for alerting the patient via the alarm of the monitor is different from the third threshold amount for communicating the instructions to the insulin pump to stop delivery of insulin; and

the second threshold amount for communicating the alert to the one or more of the at least one first electronic device and the at least one second electronic device is different from the fourth threshold amount for communicating the instructions to the glucose pump to begin delivery of glucose.

2. The system of claim 1, wherein the alarm of the monitor is adapted to visually and/or audibly alert the patient automatically in response to one of the measured blood glucose levels being below the first threshold amount.

3. The system of claim 1, wherein

one of the measured blood glucose levels being below the first threshold amount or the third threshold amount indicates that the patient has a blood glucose level in a range that is below normal for the patient;

and

one of the measured blood glucose levels being below the second threshold amount or the fourth threshold amount indicates that the patient has a blood glucose level in a range at which symptoms of hypoglycemia begin to occur.

4. The system of claim 1, the insulin pump and the glucose pump being configured for alternatively delivering therapeutic doses of insulin and therapeutic doses of glucose, respectively, such that insulin and glucose are not delivered into the patient at the same time.

5. The system of claim 1, wherein the monitor is configured to continuously or periodically communicate the measured blood glucose levels to the one or more of the at least one first electronic device associated with the at least one medical professional and the at least one second electronic device associated with the at least one emergency contact via the communication network using IEEE 802.11 wireless data transfer or short range device-to-device wireless data transfer.

6. A method for monitoring and treating hypoglycemia in a patient, the method comprising:

providing a patient care network facilitated by a web-based software application that facilitates interaction amongst a limited group of members defined by the patient care network with one another, wherein the limited group of members of the patient care network includes the patient, at least one medical professional associated with at least one first electronic device, and at least one emergency contact associated with at least one second electronic device;

providing a glucose pump configured to deliver therapeutic doses of glucose into the patient and an insulin pump configured to deliver therapeutic doses of insulin into the patient;

providing a monitor configured to measure blood glucose levels of the patient, wherein the monitor is communicatively coupled with the glucose pump, the insulin pump, the at least one first electronic device and the at least one second electronic device via a communication network;

continuously or periodically communicating the measured blood glucose levels to one or more of the at least one first electronic device and the at least one second electronic device of the patient care network via the communication network;

determining whether one or more of the measured blood glucose levels are below one or more threshold amounts; and

prompting treatment to correct low blood glucose levels of the patient in response to at least one of the measured blood glucose levels being below at least one of the one or more threshold amounts, wherein prompting treatment includes;

alerting the patient via an alarm of the monitor in response to one of the measured blood glucose levels being below a first threshold amount;

communicating an alert to one or more of the at least one first electronic device and the at least one second electronic device via the communication network in response to one of the measured blood glucose levels being below a second threshold amount that is lower than the first threshold amount;

communicating instructions to the insulin pump to stop delivery of insulin into the patient via the communication network in response to one of the measured blood glucose levels being below a third threshold amount; and

communicating instructions to the glucose pump to begin delivery of glucose into the patient via the communication network in response to one of the measured blood glucose levels being below a fourth threshold amount that is lower than the third threshold amount, wherein;

the first threshold amount for alerting the patient via the alarm of the monitor is different from the third threshold amount for communicating the instructions to the insulin pump to stop delivery of insulin; and

the second threshold amount for communicating the alert to the one or more of the at least one first electronic device and the at least one second electronic device is different from the fourth threshold amount for communicating the instructions to the glucose pump to begin delivery of glucose.

7. The method of claim 6, wherein:

one of the measured blood glucose levels being below the first threshold amount or the third threshold amount indicates that the patient has a blood glucose level in a range that is below normal for the patient; and

one of the measured blood glucose levels being below the second threshold amount or the fourth threshold amount indicates that the patient has a blood glucose level in a range at which symptoms of hypoglycemia begin to occur.

8. The method of claim 6, wherein the insulin pump and the glucose pump are configured for alternatively delivering therapeutic doses of insulin and therapeutic doses of glucose, respectively, such that insulin and glucose are not delivered into the patient at the same time.

9. The method of claim 6, wherein the alarm of the monitor is adapted to automatically visually and/or audibly alert the patient in response to one of the measured blood glucose levels below the first threshold amount.

10. The method of claim 6, wherein the method comprises continuously or periodically communicating the measured blood glucose levels to the one or more of the at least one first electronic device associated with the at least one medical professional and the at least one second electronic device associated with the at least one emergency contact of the patient care network via the communication network using IEEE 802.11 wireless data transfer or short range device-to-device wireless data transfer.

11. The method of claim 6, further comprising adjusting one or more of the first threshold amount, the second threshold amount, the third threshold amount, and the fourth threshold amount to be patient-specific.

12. An apparatus for monitoring and treating hypoglycemia in a patient, the apparatus comprising:

a memory storing computer-readable instructions; and

a processor configured to execute the computer-readable instructions to;

provide a patient care network that facilitates interaction amongst a limited group of members defined by the patient care network with one another, wherein the limited group of members of the patient care network includes the patient, at least one medical professional associated with at least one first electronic device, and at least one emergency contact associated with at least one second electronic device;

continuously or periodically receive measured blood glucose levels of the patient from a monitor via a communication network, wherein the monitor is configured to measure blood glucose levels of the patient;

continuously, periodically, or in response to a request, communicate the measured blood glucose levels of the patient to one or more of the at least one first electronic device and the at least one second electronic device of the patient care network via the communication network;

determine whether one or more of the measured blood glucose levels are below one or more threshold amounts; and

prompt treatment to correct low blood glucose levels of the patient in response to at least one of the measured blood glucose levels being below at least one of the one or more threshold amounts, wherein prompting treatment includes;

causing the monitor to alert the patient via an alarm of the monitor in response to one of the measured blood glucose levels being below a first threshold amount;

communicating an alert to one or more of the at least one first electronic device and the at least one second electronic device via the communication network in response to one of the measured blood glucose levels being below a second threshold amount that is lower than the first threshold amount;

causing an insulin pump to stop delivery of insulin into the patient in response to one of the measured blood glucose levels being below a third threshold amount; and

causing a glucose pump to begin delivery of glucose into the patient in response to one of the measured blood glucose levels being below a fourth threshold amount that is lower than the third threshold amount, wherein;

the first threshold amount for causing the monitor to alert the patient via the alarm of the monitor is different from the third threshold amount for causing the insulin pump to stop delivery of insulin; and

the second threshold amount for communicating the alert to the one or more of the at least one first electronic device and the at least one second electronic device is different from the fourth threshold amount for causing the glucose pump to begin delivery of glucose.

13. The apparatus of claim 12, wherein causing the monitor to alert the patient via the alarm includes causing the alarm to visually and/or audibly alert the patient automatically in response to one of the measured blood glucose levels being below the first threshold amount.

14. The apparatus of claim 12, wherein:

one of the measured blood glucose levels being below the first threshold amount or the third threshold amount indicates that the patient has a blood glucose level in a range that is below normal for the patient; and

one of the measured blood glucose levels being below the second threshold amount or the fourth threshold amount indicates that the patient has a blood glucose level in a range at which symptoms of hypoglycemia begin to occur.

15. The apparatus of claim 12, wherein the processor is configured to execute the computer-readable instructions to cause the insulin pump and the glucose pump to alternatively deliver therapeutic doses of insulin and therapeutic doses of glucose, respectively, such that insulin and glucose are not delivered into the patient and the same time.

16. The apparatus of claim 12, wherein the processor is configured to execute the computer-readable instructions to:

continuously or periodically receive the measured blood glucose levels from the monitor via the communication network using IEEE 802.11 wireless data transfer or short range device-to-device wireless data transfer; and

continuously, periodically, or in response to the request, communicate the measured blood glucose levels to the one or more of the at least one first electronic device associated with the at least one medical professional and the at least one second electronic device associated with the at least one emergency contact of the patient care network via the communication network using wired data transfer, cellular data transfer, IEEE 802.11 wireless data transfer, or short range device-to-device wireless data transfer.