Cardiac pacemaker with pacing pulse energy adjustment based on sensed heart rate

• US 10,821,288 B2
• Filed: 03/28/2018
• Issued: 11/03/2020
• Est. Priority Date: 04/03/2017
• Status: Active Grant

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Reddy, G. Shantanu, Schmidt, Brian L.
• Primary Examiner(s): Schaetzle, Kennedy
• Application Number:
  US15/938,719
• Publication Number:
  US 20180280702A1
• Time in Patent Office: 951 Days
• Field of Search: None
• CPC Class Codes: A61N 1/3621 for treating or preventing abnormally high heart rate
• CPC Class Codes: A61N 1/36507 controlled by gradient or slope of the heart potential
• CPC Class Codes: A61N 1/36542 controlled by body motion, e.g. acceleration
• CPC Class Codes: A61N 1/36578 controlled by mechanical motion of the heart wall, e.g. measured by an accelerometer or microphone
• CPC Class Codes: A61N 1/36585 controlled by two or more physical parameters
• CPC Class Codes: A61N 1/36592 controlled by the heart rate variability
• CPC Class Codes: A61N 1/371 Capture, i.e. successful stimulation
• CPC Class Codes: A61N 1/37205 Microstimulators, e.g. implantable through a cannula
• CPC Class Codes: A61N 1/37211 Means for communicating with stimulators
• CPC Class Codes: A61N 1/37512 Pacemakers
• CPC Class Codes: A61N 1/3756 Casings with electrodes thereon, e.g. leadless stimulators

Abstract

Implantable medical devices (IMD) such as a cardiac pacemakers may include a sensor and electrodes. In some cases, the IMD may include electronics to use the sensor to determine the heart rate of a patient'"'"'s heart. The electronics may use the electrodes to deliver pacing pulses to the heart at a first energy level if the heart rate is below a threshold and pace the heart at an enhanced energy level if the heart rate is above the threshold.

Claims

1. A cardiac pacemaker that is free from an Implantable Cardioverter Defibrillator (ICD) that is configured to provide defibrillation therapy, the cardiac pacemaker comprising:

one or more sensors for sensing one or more physiological parameters of a patient;

two or more pacing electrodes for delivering pacing pulses to the heart of the patient;

electronics operatively coupled to the one or more sensors and the two or more pacing electrodes, the electronics configured to;

determine a heart rate of the patient based at least in part on the one or more physiological parameters sensed by the one or more sensors;

pace the heart of the patient via the two or more pacing electrodes in a manner that attempts to keep the heart rate of the patient from falling below a demand heart rate threshold, wherein;

the pacing pulses are delivered at a capture pacing energy level; and

when the heart rate rises above an upper heart rate threshold, then for a temporary period of time, the pacing pulses are delivered at an enhanced energy level above the capture pacing energy level regardless of whether defibrillation therapy is delivered or not.

2. The cardiac pacemaker of claim 1, wherein the one or more sensors comprises two or more sensing electrodes, and at least one of the physiological parameters comprises a cardiac electrical signal.

3. The cardiac pacemaker of claim 1, wherein at least one of the two or more sensing electrodes is one of the pacing electrodes.

4. The cardiac pacemaker of claim 1, wherein the one or more sensors comprise an accelerometer, and at least one of the physiological parameters comprises one or more of a heart motion and a heart sound.

5. The cardiac pacemaker of claim 1, wherein the heart rate determined by the electronics is an average heart rate of “

n”

previous heart beats, wherein “

n”

is an integer greater than one.

6. The cardiac pacemaker of claim 1, wherein the pacing pulses have a first amplitude and first pulse width at the capture pacing energy level, and a second amplitude and second pulse width at the enhanced energy level, wherein the second amplitude is greater than the first amplitude and the second pulse width is the same as the first pulse width.

7. The cardiac pacemaker of claim 1, wherein the pacing pulses have a first amplitude and first pulse width at the capture pacing energy level, and a second amplitude and second pulse width at the enhanced energy level, wherein the second amplitude is the same as the first amplitude and the second pulse width is greater than the first pulse width.

8. The cardiac pacemaker of claim 1, wherein the pacing pulses have a first amplitude and first pulse width at the capture pacing energy level, and a second amplitude and second pulse width at the enhanced energy level, wherein the second amplitude is greater than the first amplitude and the second pulse width is greater than the first pulse width.

9. The cardiac pacemaker of claim 1, wherein the period of time is a predetermined period of time.

10. The cardiac pacemaker of claim 9, wherein the predetermined period of time is programmable.

11. The cardiac pacemaker of claim 1, wherein the period of time is greater than 3 minutes.

12. The cardiac pacemaker of claim 1, wherein the period of time is less than 1 hour.

13. The cardiac pacemaker of claim 1, further comprising a communication module, wherein the electronics can receive commands from a remote device via the communication module, and wherein in response to receiving an ATP command, the electronics is configured to deliver a burst of ATP pacing pulses at the enhanced energy level.

14. The cardiac pacemaker of claim 1, wherein the cardiac pacemaker is a leadless cardiac pacemaker (LCP) that is configured to be implanted within a chamber of the heart of the patient.

15. A leadless cardiac pacemaker (LCP) comprising:

a housing;

a plurality of electrodes for sensing electrical signals emanating from outside of the housing;

an energy storage module disposed within the housing;

a pulse generator for delivering pacing pulses via two or more of the plurality of electrodes, wherein the pulse generator is capable of changing an energy level of the pacing pulses;

a control module disposed within the housing and operatively coupled to the pulse generator and at least two of the plurality of electrodes, wherein the control module is configured to;

receive one or more cardiac signals via two or more of the plurality of electrodes;

determine a heart rate based at least in part on the received one or more cardiac signals;

instruct the pulse generator to pace the heart with pacing pulses of a capture pacing energy level in a manner that attempts to keep the heart rate from falling below a demand heart rate threshold;

determine if the heart rate rises above an upper heart rate threshold; and

in response to determining that the heart rate has risen above the upper heart rate threshold, regardless of whether any defibrillation therapy has been or will be initiated by a remote device, instruct the pulse generator to increase the energy level of the pacing pulses to an enhanced energy level for a temporary period of time, and after the temporary period of time, instruct the pulse generator to decrease the energy level of the pacing pulses back to the capture pacing energy level.

16. The LCP of claim 15, wherein the pulse generator changes an amplitude of the pacing pulses to increase the energy level of the pacing pulses to the enhanced energy level.

17. The LCP of claim 15, wherein the pulse generator changes a pulse width of the pacing pulses to increase the energy level of the pacing pulses to the enhanced energy level.

18. The LCP of claim 15, wherein the pulse generator changes an amplitude and a pulse width of the pacing pulses to increase the energy level of the pacing pulses to the enhanced energy level.

19. A method for pacing a heart of a patient, the method comprising:

determining a heart rate of the patient;

pacing the heart of the patient in a manner that attempts to keep the heart rate of the patient from falling below a demand heart rate threshold, wherein;

the pacing pulses are delivered at a capture pacing energy level; and

when the heart rate rises above an upper heart rate threshold, then for a period of time after rising above the upper heart rate threshold and beginning before any defibrillation shocks are delivered to the heart in response to the rising heart rate, delivering pacing pulses at an enhanced energy level above the capture pacing energy level.

20. The method of claim 19, wherein the heart rate determined by an average heart rate of “

n”

previous heart beats, wherein “

n”

is an integer greater than one.