Method of treating atherosclerotic occlusive disease

• US 10,835,395 B2
• Filed: 12/10/2013
• Issued: 11/17/2020
• Est. Priority Date: 12/12/2007
• Status: Active Grant

• Current Assignee: Intact Vascular, Inc. (Koninklijke Philips N.V.)
• Original Assignee: Intact Vascular, Inc. (Koninklijke Philips N.V.)
• Inventors: Schneider, Peter, Giasolli, Robert M.
• Primary Examiner(s): Erezo, Darwin P
• Assistant Examiner(s): Knauss, Christian D
• Application Number:
  US14/102,411
• Publication Number:
  US 20140194967A1
• Time in Patent Office: 2,534 Days
• CPC Class Codes: A61F 2/844 folded prior to deployment
• CPC Class Codes: A61F 2/848 having means for fixation to the vessel wall, e.g. barbs
• CPC Class Codes: A61F 2/86 Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/88 the wire-like elements formed as helical or spiral coils forming a net-like or mesh-like structure A61F2/90
• CPC Class Codes: A61F 2/89 the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2/92 Stents in the form of a rolled-up sheet expanding after insertion into the vessel , e.g. with a spiral shape in cross-section
• CPC Class Codes: A61F 2/95 Instruments specially adapted for placement or removal of stents or stent-grafts
• CPC Class Codes: A61F 2/958 Inflatable balloons for placing stents or stent-grafts
• CPC Class Codes: A61F 2002/823 Stents, different from stent-grafts, adapted to cover an aneurysm
• CPC Class Codes: A61F 2002/825 having longitudinal struts
• CPC Class Codes: A61F 2002/826 more than one stent being applied sequentially
• CPC Class Codes: A61F 2002/8483 Barbs
• CPC Class Codes: A61F 2002/8486 provided on at least one of the ends
• CPC Class Codes: A61F 2002/91508 the meander having a difference in amplitude along the band
• CPC Class Codes: A61F 2002/91575 connected peak to trough
• CPC Class Codes: A61F 2002/91583 by a bridge, whereby at least one of its ends is connected along the length of a strut between two consecutive apices within a band
• CPC Class Codes: A61F 2002/9665 with additional retaining means
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/0066 : stapled
• CPC Class Codes: A61F 2230/005 : Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0054 : V-shaped
• CPC Class Codes: A61F 2250/0067 : Means for introducing or releasing pharmaceutical products into the body
• CPC Class Codes: A61L 31/16 : Biologically active materials, e.g. therapeutic substances A61L31/047 takes precedence

Abstract

A tack device for holding plaque against blood vessel walls in treating atherosclerotic occlusive disease can be formed as a thin, annular band of durable, flexible material. The tack device may also have a plurality of barbs or anchoring points on its outer annular periphery. The annular band can have a length in the axial direction of the blood vessel walls that is about equal to or less than its diameter as installed in the blood vessel. A preferred method is to perform angioplasty with a drug eluting balloon as a first step, and if there is any dissection to the blood vessel caused by the balloon angioplasty, one or more tack devices may be installed to tack down the dissected area of the blood vessel surface.

Claims

1. A method of treating a blood vessel comprising:

advancing a plurality of implants held in a compressed state by an outer cover to a treatment area in a blood vessel after a balloon angioplasty has been performed at the treatment area, each of the implants of the plurality of implants having a distal most end and a proximal most end along a longitudinal axis, each of the implants of the plurality of implants comprising cells formed by first, second and third undulating rings, wherein the first undulating ring is directly connected to the second undulating ring and the second undulating ring is directly connected to the third undulating ring, and having an implant width defined by a distance between the distal most end and the proximal most end;

withdrawing the outer cover a distance;

allowing a first implant of the plurality of implants to expand against a wall of the blood vessel at the treatment area; and

expanding a second implant of the plurality of implants against the wall of the blood vessel at the treatment area, the second implant spaced away from the first implant a distance equal to at least the implant width of the second implant such that a portion of the treatment area between the first and second implants that has been treated by the balloon angioplasty includes diseased tissue that is not covered by an implant.

2. The method of claim 1, wherein the implant width is about equal to or less than a diameter of the implant when expanded in a blood vessel.

3. The method of claim 1, wherein the first and second implants and any additional implants are only applied where specific holding forces are needed to either stabilize the treatment area or hold pieces of plaque out of the way of blood flow in the treatment area.

4. The method of claim 1, wherein only half of the treatment area that has been treated by the balloon angioplasty is covered with implants.

5. The method of claim 1, wherein less than half of the treatment area that has been treated by the balloon angioplasty is covered with implants.

6. The method of claim 1, further comprising delivering plaque treatment medication to the blood vessel with at least one of the first implant and the second implant.

7. The method of claim 1, further comprising expanding one or more additional implants at a damage, disruption, dissection, or irregularity in the blood vessel caused by the balloon angioplasty, the one or more additional implants holding down the damaged, disrupted, dissected, or irregular blood vessel surface and each implant spaced away from all other implants by at least the width of the implant.