Devices, systems and methods for locating and interacting with medicament delivery systems

• US 10,839,669 B2
• Filed: 01/31/2018
• Issued: 11/17/2020
• Est. Priority Date: 12/27/2012
• Status: Active Grant

• Current Assignee: Kaleo, Inc.
• Original Assignee: Kaleo, Inc.
• Inventors: Edwards, Eric S., Edwards, Evan T., Licata, Mark J., Meyers, Paul F., Kamat, Vaishali Vilas, Gardner, Steven David, Milner, Robert George
• Primary Examiner(s): Gray, Phillip A
• Application Number:
  US15/884,769
• Publication Number:
  US 20180151053A1
• Time in Patent Office: 1,021 Days
• Field of Search: 604187
• CPC Class Codes: A61M 11/007 Syringe-type or piston-type sprayers or atomisers
• CPC Class Codes: A61M 15/00 Inhalators drug delivery in endotracheal tubes A61M16/04
• CPC Class Codes: A61M 15/0001 Details of inhalators; Constructional features thereof
• CPC Class Codes: A61M 15/08 Inhaling devices inserted into the nose
• CPC Class Codes: A61M 2005/206 With automatic needle insertion
• CPC Class Codes: A61M 2005/2073 preventing premature release, e.g. by making use of a safety lock
• CPC Class Codes: A61M 2205/14 Detection of the presence or absence of a tube, a connector or a container in an apparatus
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: A61M 2205/3306 Optical measuring means
• CPC Class Codes: A61M 2205/3375 Acoustical, e.g. ultrasonic, measuring means
• CPC Class Codes: A61M 2205/3553 remote, e.g. between patient's home and doctor's office
• CPC Class Codes: A61M 2205/3561 local, e.g. within room or hospital
• CPC Class Codes: A61M 2205/3569 sublocal, e.g. between console and disposable
• CPC Class Codes: A61M 2205/3584 using modem, internet or bluetooth
• CPC Class Codes: A61M 2205/3592 using telemetric means, e.g. radio or optical transmission
• CPC Class Codes: A61M 2205/43 making noise when used correctly
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/582 by tactile feedback
• CPC Class Codes: A61M 2205/583 : by visual feedback
• CPC Class Codes: A61M 2205/587 : Lighting arrangements
• CPC Class Codes: A61M 2205/8206 : battery-operated
• CPC Class Codes: A61M 2205/8212 : with means or measures taken for minimising energy consumption
• CPC Class Codes: A61M 2230/04 : Heartbeat characteristics, e.g. ECG, blood pressure modulation
• CPC Class Codes: A61M 2230/20 : Blood composition characteristics
• CPC Class Codes: A61M 2230/201 : Glucose concentration
• CPC Class Codes: A61M 2230/42 : Rate
• CPC Class Codes: A61M 5/20 : Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically A61M5/142 , A61M5/46 take precedence; hypodermic projectiles F42B12/54
• CPC Class Codes: A61M 5/2053 : Media being expelled from injector by pressurised fluid or vacuum for infusion A61M5/145, A61M5/155
• CPC Class Codes: A61M 5/31 : Details
• CPC Class Codes: A61M 5/3157 : Means providing feedback signals when administration is completed A61M5/20 takes precedence
• CPC Class Codes: A61M 5/3202 : Devices for protection of the needle before use, e.g. caps A61M5/50 takes precedence; for infusion spikes A61M5/1626; protectors for sharps A61B50/3001
• CPC Class Codes: A61M 5/5086 : for indicating if defective, used, tampered with or unsterile
• CPC Class Codes: G08B 21/185 : Electrical failure alarms
• CPC Class Codes: G09B 9/00 : Simulators for teaching or training purposes for the use of weapons F41; computing aspects G06; protocols for games, networked simulations or virtual reality H04L67/131
• CPC Class Codes: G16H 20/17 : delivered via infusion or injection
• CPC Class Codes: H04B 1/3827 : Portable transceivers
• CPC Class Codes: H04W 4/80 : Services using short range communication, e.g. near-field communication [NFC], radio-frequency identification [RFID] or low energy communication
• CPC Class Codes: Y02A 90/10 : Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

In some embodiments, a method includes producing, from an adapter, a first wireless signal characterized by a first communication mode with a computing device when a portion of at least one of a medicament delivery device or a simulated medicament delivery is disposed within the adapter. An indication is received when the portion of the medicament delivery device or the simulated medicament delivery device is removed from the adapter. A second wireless signal characterized by a second communication mode with the computing device is produced in response to the indication. The second communication mode is different from the first communication mode. The second communication mode can be, for example, a hold mode, a sniff mode or a park mode.

Claims

1. An apparatus, comprising:

a medicament delivery device; and

an electronic circuit system including a processor, a power source, a radio, an audible output device, and a power module, the radio configured to transmit a short-range wireless signal to be received by a computing device, the audible output device configured to produce an audible output when the medicament delivery device is transitioned from a first configuration to a second configuration, the power module implemented in at least one of a memory or the processor, the power module configured to suppress transmission of the short-range wireless signal to conserve power of the power source.

2. The apparatus of claim 1, wherein the power module is configured to suppress transmission of the short-range wireless signal while allowing production of the audible output from the audible output device.

3. The apparatus of claim 1, wherein the power module is configured to suppress transmission of the short-range wireless signal when the audible output device is producing the audible output.

4. The apparatus of claim 1, wherein:

the radio is configured to send the short-range wireless signal when the medicament delivery device is in the first configuration;

the electronic circuit system includes a sensor configured to produce a transition signal when the medicament delivery device transitions from the first configuration to the second configuration, the audible output device configured to produce the audible output in response to the transition signal; and

the power module is configured to suppress transmission of the short-range wireless signal during a time period when the audible output is being produced.

5. The apparatus of claim 4, wherein the sensor is at least one of a contact sensor, a switch, a microphone, a capacitance sensor or an optical sensor.

6. The apparatus of claim 1, wherein:

the medicament delivery device is an auto-injector having an actuator configured to initiate delivery of a medicament and a lock member configured to limit movement of the actuator, the lock member in a first position relative to the actuator when the auto-injector is in the first configuration, the lock member in a second position relative to the actuator when the auto-injector is in the second configuration.

7. The apparatus of claim 1, further comprising:

an adapter configured to receive at least a portion the medicament delivery device, the portion of the medicament delivery device being within the adapter when the medicament delivery device is in the first configuration, the portion of the medicament delivery device being outside of the adapter when the medicament delivery device is in the second configuration, the power source being electrically coupled to the radio when the medicament delivery device is in the first configuration and the second configuration.

8. The apparatus of claim 1, wherein the power source is a battery continuously providing power to the processor when the medicament delivery device is in each of the first configuration and the second configuration.

9. An apparatus, comprising:

a medicament delivery device; and

an electronic circuit system including a processor, a power source, a radio, a light output device, an audible output device, and a power module, the radio configured to transmit a short-range wireless signal to be received by a computing device, at least one of the light output device or the audible output device configured to produce an output when the medicament delivery device is transitioned from a first configuration to a second configuration, the power module implemented in at least one of a memory or the processor, the power module configured to suppress transmission of the short-range wireless signal to conserve power of the power source.

10. The apparatus of claim 9, wherein the medicament delivery device includes a housing, the apparatus further comprising:

an adapter configured to receive at least a portion the housing, the portion of the housing being within the adapter when the medicament delivery device is in the first configuration, the portion of the housing being outside of the adapter when the medicament delivery device is in the second configuration, the power source being electrically coupled to the radio when the medicament delivery device is in the first configuration and the second configuration.

11. The apparatus of claim 10, wherein the electronic circuit system is coupled to either the housing or the adapter.

12. The apparatus of claim 9, wherein:

the radio is configured to send the short-range wireless signal when the medicament delivery device is in the first configuration;

the electronic circuit system includes a sensor configured to produce a transition signal when the medicament delivery device transitions from the first configuration to the second configuration, the audible output device configured to produce an audible output in response to the transition signal; and

the power module is configured to suppress transmission of the short-range wireless signal during a time period when the audible output is being produced.

13. The apparatus of claim 9, wherein the power source is a battery continuously providing power to the processor when the medicament delivery device is in each of the first configuration and the second configuration.

14. A non-transitory processor-readable medium storing code representing instructions to be executed by a processor, the code comprising code to cause the processor to:

produce a first wireless signal characterized by a first communication interval when a medicament delivery device is in a first configuration;

receive an indication associated with the medicament delivery device being transitioned from the first configuration to a second configuration; and

produce a second wireless signal characterized by a second communication interval in response to the indication, the second communication interval different from the first communication interval.

15. The non-transitory processor-readable medium of claim 14, wherein the first wireless signal and the second wireless signal are each produced in accordance with a wireless protocol to establish electronic communication with a computing device.

16. The non-transitory processor-readable medium of claim 14, wherein at least one of the first wireless signal or the second wireless signal includes information associated with a signal power level and an identification of the medicament delivery device.

17. The non-transitory processor-readable medium of claim 14, wherein:

the first communication interval is associated with a first communication mode between an electronic circuit system and a computing device; and

the second communication interval is associated with a second communication mode between the electronic circuit system and the computing device, the second communication mode different than the first communication mode.

18. The non-transitory processor-readable medium of claim 14, wherein the indication is a first indication, at least one of the first wireless signal or the second wireless signal is associated with a first radio frequency channel, the code further comprising code to cause the processor to:

receive a second indication associated with the medicament delivery device being transitioned from the second configuration to a third configuration; and

produce, in response to the second indication, a third wireless signal associated with a second radio frequency channel, the second radio frequency channel different from the first radio frequency channel.

19. The non-transitory processor-readable medium of claim 18, wherein:

the first radio frequency channel is an advertising channel associated with a wireless protocol; and

the second radio frequency channel is a data channel associated with the wireless protocol.

20. The non-transitory processor-readable medium of claim 14, wherein the second wireless signal includes information associated with a strength of the second wireless signal and an identification of the medicament delivery device.