Infusion system and components thereof

• US 10,857,287 B2
• Filed: 07/03/2019
• Issued: 12/08/2020
• Est. Priority Date: 01/06/2017
• Status: Active Grant

• Current Assignee: BETA Bionics, Inc., Trustees of Boston University
• Original Assignee: Boston University
• Inventors: Damiano, Edward R., Selagamsetty, Rajendranath, El-Khatib, Firas H., Knodel, Bryan D., Carr, Raymond A.
• Primary Examiner(s): Eisenberg, Rebecca E
• Application Number:
  US16/503,269
• Publication Number:
  US 20190344009A1
• Time in Patent Office: 524 Days
• CPC Class Codes: A61J 1/065 Rigid ampoules, e.g. glass ampoules
• CPC Class Codes: A61J 1/1406 Septums, pierceable membranes
• CPC Class Codes: A61J 1/1481 with connection retaining means, e.g. thread or snap-fit
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2037 having valve means
• CPC Class Codes: A61J 1/2065 having aligning and guiding means
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: A61J 2200/70 Device provided with specific sensor or indicating means
• CPC Class Codes: A61J 2205/10 Bar codes
• CPC Class Codes: A61J 2205/60 using magnetic or electronic identifications, e.g. chips, RFID, electronic tags
• CPC Class Codes: A61M 2005/14573 with a replaceable reservoir for quick connection/disconnection with a driving system
• CPC Class Codes: A61M 2005/3128 Incorporating one-way valves, e.g. pressure-relief or non-return valves
• CPC Class Codes: A61M 2039/242 designed to open when a predetermined pressure or flow rate has been reached, e.g. check valve actuated by fluid
• CPC Class Codes: A61M 2205/10 with powered movement mechanisms
• CPC Class Codes: A61M 2205/586 Ergonomic details therefor, e.g. specific ergonomics for left or right-handed users
• CPC Class Codes: A61M 2205/6036 characterised by physical shape, e.g. array of activating switches
• CPC Class Codes: A61M 39/24 Check- or non-return valves
• CPC Class Codes: A61M 5/1408 in parallel, e.g. manifolds, sequencing valves access sites A61M39/02; tube connectors A61M39/10
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/14566 with a replaceable reservoir for receiving a piston rod of the pump
• CPC Class Codes: A61M 5/1684 : by detecting the amount of infusate remaining, e.g. signalling end of infusion
• CPC Class Codes: A61M 5/16881 : Regulating valves on-off valves, e.g. clamps A61M39/28

Abstract

Certain embodiments provide multi-medicament infusion systems for preventing the cross-channeling of medicaments. The system may include one or more of an infusion pump, medicament reservoirs, a multi-channel fluid conduit, and an infusion set. The medicament reservoirs and/or collars may be sized and shaped differently such that the medicament reservoirs can only be inserted into the system under selected configurations.

Claims

1. A medicament infusion system for delivering multiple medicaments to a patient, the medicament infusion system comprising:

a first reservoir set comprising;

a first inlet connector configured to engage a first medicament reservoir that comprises a first medicament reservoir port and a first medicament, the first inlet connector being configured to fit over at least a portion of the first medicament reservoir port, the first inlet connector comprising;

a first needle configured to receive the first medicament;

a first engaging member configured to engage a portion of the first medicament reservoir thereby coupling the first inlet connector to the first medicament reservoir; and

a first check valve configured to allow the first medicament to flow from the first medicament reservoir in response to a first threshold fluid pressure being applied to the first medicament;

wherein the first threshold fluid pressure is greater than a gravitationally induced hydrostatic pressure caused by placing the first reservoir set above an infusion site of the patient; and

a second reservoir set comprising;

a second inlet connector configured to engage a second medicament reservoir that comprises a second medicament reservoir port and a second medicament, the second inlet connector being configured to fit over at least a portion of the second medicament reservoir port, the second inlet connector comprising;

a second needle configured to receive the second medicament; and

a second engaging member configured to engage a portion of the second medicament reservoir thereby coupling the second inlet connector to the second medicament reservoir.

2. The medicament infusion system of claim 1, wherein the first medicament inlet connector comprises features configured to prevent coupling to the second medicament reservoir.

3. The medicament infusion system of claim 2, wherein the second medicament inlet connector comprises features configured to prevent coupling to the first medicament reservoir.

4. The medicament infusion system of claim 1, wherein the first check valve is configured to substantially prevent unintended distribution of the first medicament from the first medicament reservoir.

5. The medicament infusion system of claim 1, wherein the first needle is recessed within the first inlet connector such that the first inlet connector is configured to reduce the chance that a user contacts the first needle as the first inlet connector is handled.

6. The medicament infusion system of claim 1, wherein the second needle is recessed within the second inlet connector such that the second inlet connector is configured to reduce the chance that a user contacts the second needle as the second inlet connector is handled.

7. The medicament infusion system of claim 1, further comprising the first medicament reservoir.

8. The medicament infusion system of claim 7, further comprising the second medicament reservoir.

9. The medicament infusion system of claim 1, further comprising:

a base set comprising;

a first base unit having a first port and a first adhesive portion, the first base unit comprising a first piercing element configured to deliver the first medicament to the patient, the first adhesive portion configured to adhere the first base unit to the patient; and

a second base unit having a second port, the second base unit comprising a second adhesive portion configured to adhere the second base unit to the patient;

an infusion connector set comprising;

a first infusion connector configured to reversibly couple to the first base unit via the first port and to provide a first fluid path from the first medicament reservoir to the first port of the first base; and

a second infusion connector configured to reversibly couple to the second base unit;

wherein the first base unit comprises a first guide member that prevents engagement of the second infusion connector to the first base unit;

wherein the second base unit comprises a second guide member that prevents engagement of the first infusion connector to the second base unit.

10. The medicament infusion set of claim 9, wherein the first infusion connector comprises a flared-out edge that provides an ergonomic finger hold configured to allow the first infusion connector to be grasped by a user.

11. The medicament infusion system of claim 1, wherein the second reservoir set provides a continuous fluid path from the second medicament reservoir through the second inlet connector.

12. A medicament infusion set comprising:

a first reservoir set comprising;

a first inlet connector configured to engage a first medicament reservoir comprising a first medicament reservoir port and a first medicament, the first inlet connector comprising;

a first needle configured to allow access to the first medicament;

a first engaging member that is configured to engage a portion of the first medicament reservoir to attach the first inlet connector to the first medicament reservoir;

a first check valve configured to allow the first medicament to flow from the first medicament reservoir in response to a first threshold fluid pressure being applied to the first medicament;

wherein the first threshold fluid pressure is greater than a gravitationally induced hydrostatic pressure caused by placing the first reservoir set above an infusion site of the patient; and

a first guiding element configured to fit within a coinciding first guiding aperture of a first medicament reservoir receptacle of a pump housing of a pump; and

a second reservoir set comprising;

a second inlet connector configured to engage a second medicament reservoir comprising a second medicament reservoir port and a second medicament, the second inlet connector comprising;

a second needle configured to allow access to the second medicament;

a second engaging member configured to engage a portion of the second medicament reservoir to attach the second inlet connector to the second medicament reservoir; and

a second guiding element configured to fit within a coinciding second guiding aperture of a second medicament reservoir receptacle of the pump housing of the pump.

13. The medicament infusion set of claim 12, wherein the medicament infusion set comprises the second medicament reservoir.

14. The medicament infusion set of claim 12, wherein the second reservoir set provides a continuous fluid path from the second medicament reservoir through the second inlet connector.