Multi-rate analyte sensor data collection with sample rate configurable signal processing

• US 10,874,336 B2
• Filed: 10/12/2016
• Issued: 12/29/2020
• Est. Priority Date: 03/15/2013
• Status: Active Grant

• Current Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Inventors: Budiman, Erwin Satrya
• Primary Examiner(s): Winakur, Eric F
• Application Number:
  US15/292,107
• Publication Number:
  US 20170027483A1
• Time in Patent Office: 1,539 Days
• CPC Class Codes: A61B 2562/0295 Strip shaped analyte sensors for apparatus classified in A61B5/145 or A61B5/157 disposable multilayered or laminated electrodes G01N27/307; details of handling chemical test elements G01N33/4875
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/72 Signal processing specially adapted for physiological signals or for diagnostic purposes character recognition, recognising digital ink, document-oriented image-based pattern recognition G06V30/00; recognition or understanding of postal images G06V30/424
• CPC Class Codes: A61B 5/7225 Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation A61B5/30, A61B5/316 take precedence; transformers for specific applications H01F38/00; amplifiers H03F
• CPC Class Codes: A61B 5/725 using specific filters therefor, e.g. Kalman or adaptive filters A61B5/316 take precedence
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: G16H 10/60 for patient-specific data, e.g. for electronic patient records

Abstract

Systems, methods and apparatus are provided for determining an estimate of an analyte level over time. The invention includes sampling sensor data using an analyte sensor positioned at least partially subcutaneously; storing a plurality of datasets of sensor data, each at a different rate; determining an estimated analyte level based on the datasets; and outputting the estimated analyte level to a display. Numerous additional aspects are disclosed.

Claims

1. An apparatus comprising:

one or more processors configured to receive signals generated by an analyte sensor; and

a memory storing instructions which, when executed by the one or more processors, causes the one or more processors to;

store a first dataset associated with the signals generated by the analyte sensor at a first rate in a first memory buffer; and

store a second dataset associated with the signals generated by the analyte sensor at a second rate in a second memory buffer at least in part concurrently with the storing of the first dataset.

2. The apparatus of claim 1, wherein the first memory buffer has a size that is different than a size of the second memory buffer.

3. The apparatus of claim 1, wherein the first memory buffer and the second memory buffer are separate memory buffers within a single memory device.

4. The apparatus of claim 1, wherein the first dataset and the second dataset have different data densities from each other.

5. The apparatus of claim 1, wherein the memory storing instructions which, when executed by the one or more processors, causes the one or more processors to determine an estimated analyte level by:

generating a composite dataset based on a selection of all or a subset of data points from the first dataset and the second dataset;

determining a set of filter parameters based on rates of the composite dataset; and

determining the estimated analyte level based on one or more filters using the set of filter parameters and the composite dataset.

6. The apparatus of claim 1, wherein the first rate corresponds to a size of the first memory buffer, and wherein the second rate corresponds to a size of the second memory buffer.

7. The apparatus of claim 1, wherein the analyte sensor samples data at a constant sampling rate, and wherein the first rate and the second rate are each based on fractions of the sampling rate.

8. The apparatus of claim 1, wherein the memory storing instructions which, when executed by the one or more processors, causes the one or more processors to transfer the first dataset and the second dataset to a receiver for processing.

9. The apparatus of claim 8, wherein the receiver comprises a display.

10. A system for determining an estimate of an analyte level over time, the system comprising:

an analyte sensor for generating signals corresponding to a monitored analyte level, wherein a portion of the analyte sensor is configured to be in contact with a fluid under a skin layer; and

sensor electronics operatively coupled to the analyte sensor to receive the generated signals, the sensor electronics comprising;

one or more processors; and

a memory storing instructions which, when executed by the one or more processors, causes the one or more processors to store a plurality of datasets associated with the generated signals corresponding to the monitored analyte level in a different memory buffer for each of the plurality of datasets, each of the plurality of datasets being stored at a different rate from, and at least in part concurrently with, at least one other of the plurality of datasets.

11. The system of claim 10, wherein each of the rates of storage varies depending on a rate of change of the generated signals corresponding to the monitored analyte level.

12. The system of claim 10, wherein each memory buffer of the sensor electronics has a size that is different from the sizes of the other memory buffer.

13. The system of claim 10, wherein the memory buffers of the sensor electronics are all within a single memory device.

14. The system of claim 10, wherein each of the datasets has a different data density from each other.

15. The system of claim 10, wherein the rate of storage of each of the plurality of datasets corresponds to a size of the memory buffer in which data is being stored.

16. The system of claim 10, wherein the analyte sensor samples data at a constant sampling rate, and wherein each of the rates of storage is based on fractions of the sampling rate.

17. The system of claim 10, further comprising a receiving device, and wherein the memory of the sensor electronics storing instructions which, when executed by the one or more processors, causes the one or more processors to transfer the plurality of datasets to the receiving device for processing.

18. The system of claim 17, wherein the receiving device comprises a display, and wherein the receiving device is configured to estimate the analyte level, and to output the estimated analyte level to the display of the receiving device.

19. The system of claim 18, wherein the receiving device is configured to estimate the analyte level by:

generating a composite dataset based on a selection of all or a subset of data points from the plurality of datasets;

determining a set of filter parameters based on rates of the composite dataset; and

determining an estimated analyte level based on one or more filters using the set of filter parameters and the composite dataset.

20. An apparatus comprising:

one or more processors configured to receive signals generated by an analyte sensor; and

a memory storing instructions which, when executed by the one or more processors, causes the one or more processors to;

store a first dataset associated with the signals generated by the analyte sensor at a first rate in a first memory buffer;

store a second dataset associated with the signals generated by the analyte sensor at a second rate in a second memory buffer at least in part concurrently with the storing of the first dataset; and

output historical analyte data in real time based on the first dataset and second dataset.