Adsorbing material for multiple pathogenic factors of sepsis as well as preparation method and application thereof

  • US 10,898,632 B2
  • Filed: 10/27/2016
  • Issued: 01/26/2021
  • Est. Priority Date: 10/29/2015
  • Status: Active Grant
First Claim
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1. A preparation method of a ligand of adsorbing materials for adsorbing multiple pathogenic factors of sepsis in fluids, comprising the following steps:

  • 1) In dichloromethane, compound 1 reacts with di-tert-butyl dicarbonate to generate compound 2, reaction temperature is 20˜

    30°

    C., the equivalence ratio of compound 1 and di-tert-butyl dicarbonate is 1;

    0.5˜

    2, reaction equation is

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