Electrowetting ophthalmic devices including an elastic electrode

• US 10,905,545 B2
• Filed: 04/03/2018
• Issued: 02/02/2021
• Est. Priority Date: 05/05/2017
• Status: Active Grant

• Current Assignee: Twenty Twenty Therapeutics, LLC
• Original Assignee: Verily Life Sciences LLC (Alphabet Inc.)
• Inventors: Otts, Daniel B., Kuiper, Stein
• Primary Examiner(s): Willse, David H
• Assistant Examiner(s): Blanco, Javier G
• Application Number:
  US15/944,298
• Publication Number:
  US 20180318067A1
• Time in Patent Office: 1,036 Days
• CPC Class Codes: A61F 2/1635 for changing shape
• CPC Class Codes: A61F 2/482 Electrical means
• CPC Class Codes: A61F 2210/0014 using shape memory or superelastic materials, e.g. nitinol
• CPC Class Codes: A61F 2250/0001 Means for transferring electromagnetic energy to implants
• CPC Class Codes: A61F 2250/0002 for data transfer
• CPC Class Codes: A61F 2250/0003 having an inflatable pocket filled with fluid, e.g. liquid or gas
• CPC Class Codes: A61F 2250/0018 differing in elasticity, stiffness or compressibility
• CPC Class Codes: A61F 2250/0056 differing in wettability, e.g. in hydrophilic or hydrophobic behaviours
• CPC Class Codes: A61L 31/022 Metals or alloys
• CPC Class Codes: A61L 31/06 obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds A61L31/041 takes precedence
• CPC Class Codes: A61L 31/088 Other specific inorganic materials not covered by A61L31/084 or A61L31/086
• CPC Class Codes: G02B 26/005 based on electrowetting
• CPC Class Codes: G02B 3/14 of variable focal length
• CPC Class Codes: G02B 7/02 for lenses supports for magnifying lenses G02B25/002
• CPC Class Codes: G02C 7/085 Fluid-filled lenses, e.g. electro-wetting lenses

Abstract

Ophthalmic devices having elastic electrodes are disclosed herein. An example ophthalmic device may be an intraocular lens that includes a support structure, two optical windows, two immiscible fluids, and an elastic electrode. The support structure may have an inner surface defining an aperture with first and second optical windows disposed on opposite sides of the support structure and spanning the aperture. The two immiscible liquids may be disposed in a cavity formed by the aperture and the first and second optical windows, and the elastic electrode may be disposed on the inner surface. The elastic electrode may be formed from an elastic metal alloy having a minimum yield strain of 0.25%.

Claims

1. An ophthalmic device comprising:

a support structure;

first and second optical windows disposed on opposite sides of the support structure;

two immiscible fluids disposed in a cavity formed by the support structure and the first and second optical windows; and

an elastic electrode disposed on an inner surface of the support structure within the cavity and encircling the cavity, wherein the elastic electrode is formed from an elastic metal alloy having a minimum yield strain of 0.25%, and wherein the elastic electrode is formed from a foil of the elastic metal alloy.

2. The ophthalmic device of claim 1, wherein elastic metal alloy is a shape-memory alloy.

3. The ophthalmic device of claim 2, wherein the shape-memory alloy is selected from one of Nitinol, copper-zinc-aluminum, copper-aluminum, copper-aluminum-nickel, and copper-aluminum-beryllium.

4. The ophthalmic device of claim 1, wherein the elastic metal alloy is valve-metal coated.

5. The ophthalmic device of claim 4, wherein the valve metal is titanium.

6. The ophthalmic device of claim 1, wherein the elastic metal alloy is spring steel.

7. The ophthalmic device of claim 1, wherein the elastic metal alloy is Ti6Al4V.

8. The ophthalmic device of claim 1, wherein the elastic electrode includes a flange that extends from one edge of the elastic electrode.

9. The ophthalmic device of claim 8, wherein the flange forms a tab.

10. The ophthalmic device of claim 1, wherein the elastic electrode has a conical-shaped surface.

12. The ophthalmic device of claim 1, further comprising first and second dielectric layers disposed on the elastic electrode,

wherein the first dielectric layer is formed from a material selected from one of Parylene-C, Parylene-N, Parylene-D, Parylene-HT, and Parylene-AF4, and

wherein the second dielectric layer is formed from a fluoropolymer.

13. The ophthalmic device of claim 1, wherein the inner surface has a conical frustum shape and is truncated at an inner most diameter of the conical frustum shape,

wherein the support structure further includes first and second recesses formed on a top side and a bottom side, respectively, the first and second recesses encircling the aperture,

wherein the first recess is defined by a first surface normal to a top surface of the top side, and a second surface normal to the first surface and extending toward the inner surface,

wherein the second recess is defined by a third surface normal to a bottom surface of the bottom side, and a fourth surface normal to the third surface and extending toward the inner surface, and

wherein a portion of the first optical window is disposed in the first recess, and a portion of the second optical window is disposed in the second recess.

14. The ophthalmic device of claim 1, further including control electronics electrically coupled to the elastic electrode, wherein at least the elastic electrode and the two immiscible fluids form a dynamic optic controlled by the control electronics,

wherein an interface between the two immiscible fluids forms a lens of the dynamic optic, and

wherein the two immiscible fluids include an oil and an electrolyte.

11. The ophthalmic device 10, wherein the elastic electrode has a triangular-shaped cross-section having a back surface opposite the conical-shaped surface, the back surface extending from a flange-like top surface to an underside surface, and

wherein a thickness of the elastic electrode at the back surface is thicker than the elastic electrode along the conical-shaped surface.

15. An ophthalmic device, comprising:

a support structure of an intraocular lens, the support structure having top and bottom sides, and an inner surface forming an aperture, wherein the inner surface is at an oblique angle to the top and bottom sides of the support structure, and wherein the support structure is formed from a biocompatible material; and

an elastic electrode disposed on the inner surface to electrically induce electrowetting in the intraocular lens and encircling the cavity, the elastic electrode formed from an elastic metal alloy having a minimum yield strain of 0.25%.

16. The ophthalmic device of claim 15, wherein the elastic metal alloy is a shape-memory alloy.

17. The ophthalmic device of claim 16, wherein the shape memory alloy is selected from one of Nitinol, copper-zinc-aluminum, copper-aluminum, copper-aluminum-nickel, and copper-aluminum-beryllium.

18. The ophthalmic device of claim 16, wherein the shape memory alloy is titanium-coated Nitinol or an anodized Nitinol.

19. The ophthalmic device of claim 15, wherein the elastic electrode is formed from a foil of the elastic metal alloy, and wherein the elastic electrode includes a flange that extends from one edge of the elastic electrode.

20. The ophthalmic device of claim 19, wherein the flange extends partially onto a surface of a recess formed in the support structure.

21. The ophthalmic device of claim 19, wherein the flange extends around a circumference of the aperture.

22. The ophthalmic device of claim 19, wherein the flange forms a tab.

23. The ophthalmic device of claim 15, further comprising:

first and second optical windows disposed on the top and bottom sides of the support structure, respectively, and extending over the aperture;

a dielectric layer disposed on the elastic electrode;

a polymer layer disposed on the dielectric layer;

two immiscible fluids disposed in the aperture of the support structure and contained by the first and second optical windows; and

control electronics electrically coupled to the elastic electrode and the first optical window, wherein the control electronics provide a voltage to the elastic electrode and the first optical window to induce the electrowetting by altering a wetting characteristic of the polymer layer to cause a change in shape to an interface between the two immiscible fluids.

24. The ophthalmic device of claim 23, wherein the dielectric layer is formed from one of Parylene-C, Parylene-N, Parylene-D, Parylene-HT, and Parylene-AF4, and

wherein the polymer layer is fluoropolymer.

25. An ophthalmic device comprising:

a support structure;

first and second optical windows disposed on opposite sides of the support structure;

two immiscible fluids disposed in a cavity formed by the support structure and the first and second optical windows; and

an elastic electrode disposed on an inner surface of the support structure within the cavity and encircling the cavity, wherein the elastic electrode is formed from an elastic metal alloy having a minimum yield strain of 0.25%, and wherein the ophthalmic device is configured to be folded or rolled up without experiencing inelastic deformation upon unfolding or unrolling.