Indirect attachment of a needle to a mesh suture

• US 11,064,996 B2
• Filed: 03/04/2019
• Issued: 07/20/2021
• Est. Priority Date: 02/23/2012
• Status: Active Grant

• Current Assignee: Northwestern University
• Original Assignee: Northwestern University
• Inventors: Dumanian, Gregory A.
• Primary Examiner(s): Nguyen, Vi X
• Application Number:
  US16/291,498
• Publication Number:
  US 20190192142A1
• Time in Patent Office: 869 Days
• CPC Class Codes: A61B 17/06 Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials puncturing needles A61B17/34; hypodermic needles A61M5/32 ; sewing needles D05B85/00
• CPC Class Codes: A61B 17/06166 Sutures suture materials A61L17/00; manufacture of artificial threads D01D; treatment of threads D06M
• CPC Class Codes: A61B 2017/00526 Methods of manufacturing
• CPC Class Codes: A61B 2017/0412 having anchoring barbs or pins extending outwardly from suture anchor body
• CPC Class Codes: A61B 2017/0417 T-fasteners
• CPC Class Codes: A61B 2017/0461 with features cooperating with special features on the suture, e.g. protrusions on the suture
• CPC Class Codes: A61B 2017/0464 for soft tissue
• CPC Class Codes: A61B 2017/06009 having additional means for releasably clamping the suture to the needle, e.g. actuating rod slideable within the needle
• CPC Class Codes: A61B 2017/0608 J-shaped
• CPC Class Codes: A61B 2017/061 hollow or tubular suture extending inside a hollow needle A61B2017/06052; hollow sutures A61B2017/06185
• CPC Class Codes: A61B 2017/06185 hollow or tubular hollow suture needles A61B2017/061
• CPC Class Codes: A61L 17/00 Materials for surgical sutures or for ligaturing blood vessels surgical adhesives A61L24/00; surgical instruments, devices or methods for suturing or ligaturing A61B17/04, A61B17/12; supports or packages for suture materials A61B17/04; Materials for prostheses or catheters bone cements or surgical adhesives for soft body tissues A61L24/00; shape or structure of prostheses A61F2/00; shape or structure of catheters A61M5/00
• CPC Class Codes: A61L 17/04 Non-resorbable materials
• CPC Class Codes: A61L 17/12 Homopolymers or copolymers of glycolic acid or lactic acid
• CPC Class Codes: A61L 17/145 Coating
• CPC Class Codes: Y10T 29/49826 Assembling or joining

Abstract

A medical device includes a surgical needle, an elongated suture, and an intervening segment. The elongated suture has a first end proximate to the needle and a second end located away from the needle. The elongated suture also includes a plurality of fibers defining a mesh wall between the first and second ends. A plurality of pores extend through the mesh wall, at least some which are in the macroporous size range of greater than 200 microns for facilitating tissue integration when introduced into a body. The intervening segment is disposed between and connected to either or both ends of the elongated suture and the needle. The intervening segment includes one or more fibers of the plurality of fibers and has a cross-sectional dimension smaller than a cross-sectional dimension of the mesh wall such that the intervening segment facilitates indirect attachment of the elongated macroporous mesh suture to the needle.

Claims

1. A medical device comprising:

a surgical needle;

an elongate suture having a first end attached to the surgical needle and a second end located away from the surgical needle, the elongate suture including a plurality of fibers defining a mesh wall extending between the first end and the second end, and a plurality of pores extending through the mesh wall, wherein each of the pores has a pore size in a macroporous size range of 200 microns to 4 millimeters, and wherein the pores are adapted to facilitate tissue integration through the mesh wall when the elongate suture is introduced into a body; and

multiple intervening segments disposed between attaching the first end of the elongate suture and the surgical needle, wherein the multiple intervening segments are connected together to attach the surgical needle to the first end of the elongate suture.

2. The medical device of claim 1, wherein the multiple intervening segments comprise:

a first intervening segment connected to the first end of the elongate suture; and

a second intervening segment connected to the surgical needle.

3. The medical device of claim 2, wherein the first intervening segment comprises one or more fibers of the plurality of fibers extending from the first end of the mesh suture and having a cross-sectional dimension that is smaller than a cross-sectional dimension of the mesh wall.

4. The medical device of claim 3, wherein the first intervening segment comprises more than one of the plurality of fibers converging into a bundled configuration.

5. The medical device of claim 4, wherein at least some of the more than one fibers in the first intervening segment are fixed to each other via a process selected from the group consisting of annealed together, welded together, staked together, adhered together, bonded together, and loosely bonded together.

6. The medical device of claim 5, wherein the more than one fibers are arranged in a configuration selected from the group consisting of (a) tapered from the mesh wall into the bundled configuration, (b) disposed in a braided configuration, (c) disposed in a knit configuration, and (d) disposed in a generally parallel configuration.

7. The medical device of claim 3, wherein the first intervening segment further comprises one of a male or a female locking feature and the second intervening segment comprises the other of the male or the female locking feature for attaching to the first intervening segment.

8. The medical device of claim 7, wherein the male and female locking features are constructed of rigid biocompatible material.

9. The medical device of claim 3, wherein the second intervening segment comprises a collar having a first end into which the first intervening segment is secured and a second end into which a protrusion on the needle is secured.

10. The medical device of claim 1, wherein the mesh wall of the elongate suture comprises a hollow tubular mesh wall defining a hollow core.

11. The medical device of claim 10, wherein the hollow tubular mesh wall includes a diameter that is larger than a diameter of the multiple intervening segments.

12. The medical device of claim 11, wherein the diameter of the hollow tubular mesh wall is in a range of 1 mm to 10 mm.

13. The medical device of claim 1, wherein the mesh wall of the elongate suture comprises a planar mesh wall having a width and a thickness that is smaller than the width.

14. The medical device of claim 13, wherein the width of the planar mesh wall is greater than a diameter of the intervening segment.

15. The medical device of claim 14, wherein the width of the planar mesh wall is in a range of 1 mm to 10 mm.

16. The medical device of claim 1, wherein the elongate suture is constructed of a material selected from the group consisting of:

polyethylene terephthalate, nylon, polyolefin, polypropylene, silk, polymers p-dioxanone, co-polymer of p-dioxanone, ε

-caprolactone, glycolide, L(−

)-lactide, D(+)-lactide, meso-lactide, trimethylene carbonate, polydioxanone homopolymer, metal fibers, poly-4-hydroxybutyrate, steel, titanium, fibers derived from spider silk, graphene, and combinations thereof.

17. The medical device of claim 1, wherein the mesh wall comprises a material selected from the group consisting of a woven material, a braided material, and a knitted material.

18. The medical device of claim 1, wherein the elongate suture is at least 20 cm in length.