Analyzing apparatus and analyzing method

• US 11,138,723 B2
• Filed: 07/21/2017
• Issued: 10/05/2021
• Est. Priority Date: 07/22/2016
• Status: Active Grant

• Current Assignee: Canon Medical Systems Corporation (Canon Inc.)
• Original Assignee: Canon Medical Systems Corporation (Canon Inc.)
• Inventors: Honjo, Yasunori, Igarashi, Yu, Watanabe, Masaki
• Primary Examiner(s): Bhatnagar, Anand P
• Application Number:
  US15/656,599
• Publication Number:
  US 20180025492A1
• Time in Patent Office: 1,537 Days
• CPC Class Codes: A61B 5/7271 Specific aspects of physiological measurement analysis A61B5/316, A61B5/349 and A61B5/374 take precedence
• CPC Class Codes: A61B 5/7475 User input or interface means, e.g. keyboard, pointing device, joystick
• CPC Class Codes: A61B 8/485 involving measuring strain or elastic properties
• CPC Class Codes: A61B 8/5223 for extracting a diagnostic or physiological parameter from medical diagnostic data for algorithms to analyse biomedical images G06T7/0012
• CPC Class Codes: G06T 11/60 Editing figures and text; Combining figures or text
• CPC Class Codes: G06T 2207/10132 Ultrasound image
• CPC Class Codes: G06T 2207/20021 Dividing image into blocks, subimages or windows
• CPC Class Codes: G06T 2207/20081 Training; Learning
• CPC Class Codes: G06T 2207/30004 Biomedical image processing
• CPC Class Codes: G06T 2207/30024 Cell structures in vitro; Tissue sections in vitro
• CPC Class Codes: G06T 2210/41 Medical
• CPC Class Codes: G06T 7/0012 Biomedical image inspection
• CPC Class Codes: G06T 7/11 Region-based segmentation
• CPC Class Codes: G06T 7/187 involving region growing; involving region merging; involving connected component labelling
• CPC Class Codes: G06V 10/50 by performing operations within image blocks; by using histograms, e.g. histogram of oriented gradients [HoG]; by summing image-intensity values; Projection analysis
• CPC Class Codes: G16H 50/30 for calculating health indices; for individual health risk assessment

Abstract

An analyzing apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to calculate a tissue characteristic parameter value with respect to each of a plurality of positions within a region of interest, by analyzing a result of a scan performed on a patient. The processing circuitry is configured to determine a measurement region in the region of interest by performing an analysis while using the tissue characteristic parameter values. The processing circuitry is configured to calculate a statistic value of the tissue characteristic parameter values in the measurement region.

Claims

1. An analyzing apparatus comprising processing circuitry configured:

to calculate, with respect to each of a plurality of positions within a region of interest for a scan performed when a shear wave propagates through a body of a patient, at least one of shear velocity values, arrival times, elasticity modulus values, velocity values, displacement values, and strain values, by analyzing a result of the scan performed on the patient;

to determine a measurement region in the region of interest based on the calculated values; and

to calculate a statistic value of at least one of shear velocity values, arrival times, elasticity modulus values, velocity values, displacement values, and strain values in the measurement region.

2. The analyzing apparatus according to claim 1, wherein

the processing circuitry calculates an index value related to variance among the calculated values with respect to each of a plurality of sub-regions included in the region of interest, and

the processing circuitry determines the measurement region by comparing the index value of each of the plurality of sub-regions with a threshold value.

3. The analyzing apparatus according to claim 2, wherein the processing circuitry causes the sub-regions to be displayed into an image based on the calculated values.

4. The analyzing apparatus according to claim 2, wherein the processing circuitry receives an input to change a size of the sub-regions.

5. The analyzing apparatus according to claim 2, wherein the processing circuitry receives an input to change the threshold value.

6. The analyzing apparatus according to claim 5, wherein the processing circuitry determines the measurement region by comparing the index value of each of the plurality of sub-regions with the changed threshold value.

7. The analyzing apparatus according to claim 5, wherein the processing circuitry receives, as the input, an instruction of an operator to change the threshold value.

8. The analyzing apparatus according to claim 5, wherein the processing circuitry is further configured to re-determine a measurement region in the region of interest based on comparison between the changed threshold value and at least one of the calculated values.

9. The analyzing apparatus according to claim 8, wherein the processing circuitry is further configured to cause the re-determined measurement region to be displayed into an image based on the calculated values.

10. The analyzing apparatus according to claim 2, wherein the processing circuitry changes the threshold value in accordance with a site of the patient subject to a measuring process.

11. The analyzing apparatus according to claim 2, wherein, as the index value, the processing circuitry calculates one selected from among a variance value, a standard deviation, and a residual sum of squares, with respect to the calculated values.

12. The analyzing apparatus according to claim 2, wherein the processing circuitry determines the threshold value based on a site of the patient subject to the scan.

13. The analyzing apparatus according to claim 12, wherein an arrangement is acceptable in which an appropriate threshold value is registered in advance for each of various sites, and the processing circuitry determines the threshold value by reading a threshold value corresponding to the site designated by an operator.

14. The analyzing apparatus according to claim 1, wherein

the processing circuitry obtains distribution information of the calculated values with respect to each of a plurality of sub-regions included in the region of interest,

the processing circuitry calculates an index value indicating a degree of stability of the calculated values for each of the sub-regions, by using the distribution information as an input to a trained machine learning scheme, and

the processing circuitry determines the measurement region by comparing the index value of each of the plurality of sub-regions with a threshold value.

15. The analyzing apparatus according to claim 1, wherein the processing circuitry causes the measurement region to be displayed into an image based on the calculated values.

16. The analyzing apparatus according to claim 1, wherein, as the statistic value, the processing circuitry calculates one selected from among an average value, a median, a variance value, a standard deviation, and a residual sum of squares, with respect to the calculated values.

17. The analyzing apparatus according to claim 1, wherein the processing circuitry calculates, by analyzing a result of a MRI scan performed on the patient, at least one of the shear velocity values, the arrival times, the elasticity modulus values, the velocity values, the displacement values, and the strain values.

18. The analyzing apparatus according to claim 1, wherein the scan is performed such that an ultrasound probe transmits an observation-purpose pulse in order to observe the shear wave caused by a push pulse transmitted from the ultrasound probe.

19. An analyzing apparatus comprising processing circuitry configured:

to calculate, with respect to each of a plurality of positions within a region of interest for a scan performed when a shear wave propagates through a body of a patient, at least one of shear velocity values, arrival times, elasticity modulus values, velocity values, displacement values, and strain values, by analyzing a result of the scan performed on the patient;

to determine a measurement candidate region in the region of interest based on the calculated values; and

to cause the measurement candidate region to be displayed into an image.

20. The analyzing apparatus according to claim 19, wherein

the processing circuitry calculates an index value related to variance among the calculated values, with respect to each of a plurality of sub-regions included in the region of interest, and

the processing circuitry determines the measurement candidate region by comparing the index value of each of the plurality of sub-regions with a threshold value.

21. The analyzing apparatus according to claim 20, wherein the processing circuitry causes the sub-regions to be displayed into the image based on the calculated values.

22. The analyzing apparatus according to claim 20, wherein the processing circuitry determines one or more measurement candidate regions, from within a region combining together two or more of the sub-regions that are each determined, as a result of the comparison, to have a small value as the variance.

23. The analyzing apparatus according to claim 22, wherein the processing circuitry determines one or more measurement candidate regions of which a quantity is determined in advance.

24. The analyzing apparatus according to claim 22, wherein, as the measurement candidate region, the processing circuitry determines a circular region having a largest diameter.

25. The analyzing apparatus according to claim 19, wherein

the processing circuitry obtains distribution information of the calculated values with respect to each of a plurality of sub-regions included in the region of interest,

the processing circuitry calculates an index value indicating a degree of stability of the calculated values for each of the sub-regions, by using the distribution information as an input to a trained machine learning scheme, and

the processing circuitry determines the measurement candidate region by comparing the index value of each of the plurality of sub-regions with a threshold value.

26. The analyzing apparatus according to claim 25, wherein the processing circuitry determines one or more measurement candidate regions from within a region combining together two or more of the sub-regions that are each determined, as a result of the comparison, to exhibit a high level as the degree of stability.

27. The analyzing apparatus according to claim 19, wherein the processing circuitry determines the measurement candidate region having a shape and a size that are set in advance.

28. The analyzing apparatus according to claim 19, wherein the image is at least one of B-mode image, a firmness image, and a region image in which firmness levels of tissue in the body of the patient are displayed.

29. The analyzing apparatus according to claim 19, wherein the scan is performed such that an ultrasound probe transmits an observation-purpose pulse in order to observe the shear wave caused by a push pulse transmitted from the ultrasound probe.

30. An analyzing method comprising:

calculating, with respect to each of a plurality of positions within a region of interest for a scan performed when a shear wave propagates through a body of a patient, at least one of shear velocity values, arrival times, elasticity modulus values, velocity values, displacement values, and strain values, by analyzing a result of the scan performed on the patient;

determining a measurement region in the region of interest based on the calculated values; and

calculating a statistic value of at least one of shear velocity values, arrival times, elasticity modulus values, velocity values, displacement values, and strain values in the measurement region.

31. The analyzing method according to claim 30, wherein the scan is performed such that an ultrasound probe transmits an observation-purpose pulse in order to observe the shear wave caused by a push pulse transmitted from the ultrasound probe.

32. An analyzing method comprising:

calculating, with respect to each of a plurality of positions within a region of interest for a scan performed when a shear wave propagates through a body of a patient, at least one of shear velocity values, arrival times, elasticity modulus values, velocity values, displacement values, and strain values, by analyzing a result of the scan performed on the patient;

determining a measurement candidate region in the region of interest based on the calculated values; and

causing the measurement candidate region to be displayed into an image.

33. The analyzing method according to claim 32, wherein the scan is performed such that an ultrasound probe transmits an observation-purpose pulse in order to observe the shear wave caused by a push pulse transmitted from the ultrasound probe.

34. An analyzing apparatus comprising processing circuitry configured:

to calculate, with respect to each of a plurality of positions within a region of interest for a scan performed when a shear wave propagates through a body of a patient, parameter values based on a shear wave, by analyzing a result of the scan performed on the patient;

to determine a measurement region in the region of interest based on the calculated values; and

to calculate a statistic value of the parameter values in the measurement region.

35. The analyzing apparatus according to claim 34, wherein the scan is performed such that an ultrasound probe transmits an observation-purpose pulse in order to observe the shear wave caused by a push pulse transmitted from the ultrasound probe.

36. An analyzing apparatus comprising processing circuitry configured:

to calculate, with respect to each of a plurality of positions within a region of interest for a scan performed when a shear wave propagates through a body of a patient, parameter values based on a shear wave, by analyzing a result of the scan performed on the patient;

to determine a plurality of measurement candidate regions in the region of interest based on the calculated values; and

to select a measurement region from the plurality of measurement candidate regions.

37. The analyzing apparatus according to claim 36, wherein the scan is performed such that an ultrasound probe transmits an observation-purpose pulse in order to observe the shear wave caused by a push pulse transmitted from the ultrasound probe.