Composition in powder form comprising iron-milk protein complexes and probiotic bacteria

• US 11,191,809 B2
• Filed: 12/14/2017
• Issued: 12/07/2021
• Est. Priority Date: 12/15/2016
• Status: Active Grant

• Current Assignee: Societe des Produits Nestle SA (Nestle SA)
• Original Assignee: Societe des Produits Nestle SA (Nestle SA)
• Inventors: Bourqui, Bertrand, Husny, Joeska
• Primary Examiner(s): Berke-Schlessel, David W
• Application Number:
  US16/462,391
• Publication Number:
  US 20190314451A1
• Time in Patent Office: 1,454 Days
• CPC Class Codes: A23K 20/20 Inorganic substances, e.g. oligoelements
• CPC Class Codes: A23L 33/135 Bacteria or derivatives thereof, e.g. probiotics
• CPC Class Codes: A23L 33/165 Complexes or chelates
• CPC Class Codes: A23L 33/19 Dairy proteins
• CPC Class Codes: A23L 33/40 Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
• CPC Class Codes: A23P 10/40 free-flowing powder or instant powder, i.e. powder which is reconstituted rapidly when liquid is added A23P10/20, A23P10/30 take precedence
• CPC Class Codes: A23V 2002/00 Food compositions, function of food ingredients or processes for food or foodstuffs
• CPC Class Codes: A23V 2200/00 Function of food ingredients
• CPC Class Codes: A23V 2200/214 Chelating agent
• CPC Class Codes: A23V 2200/3204 Probiotics, living bacteria to be ingested for action in the digestive tract
• CPC Class Codes: A23V 2250/00 Food ingredients
• CPC Class Codes: A23V 2250/1592 Iron
• CPC Class Codes: A23V 2250/5424 Dairy protein
• CPC Class Codes: A23V 2250/54246 Casein
• CPC Class Codes: A23V 2400/165 Paracasei
• CPC Class Codes: A23V 2400/175 Rhamnosus
• CPC Class Codes: A23V 2400/533 Longum
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 31/295 Iron group metal compounds
• CPC Class Codes: A61K 33/26 Iron; Compounds thereof
• CPC Class Codes: A61K 35/20 : Milk; Whey; Colostrum
• CPC Class Codes: A61K 35/745 : Bifidobacteria
• CPC Class Codes: A61K 35/747 : Lactobacilli, e.g. L. acidophilus or L. brevis
• CPC Class Codes: A61K 38/1709 : from mammals

Abstract

The present invention relates to a composition in powder form comprising probiotic bacteria and at least one iron-milk protein complex. Such iron-milk protein complex advantageously does not cause significant reduction in the viability of the bacteria and thus such iron source is advantageously used to fortify a composition in powder form comprising probiotic bacteria.

Claims

1. A composition in powder form, the composition comprising at least one probiotic bacteria and further comprising an iron-milk protein complex in which the milk protein is selected from the group consisting of casein, a casein derivative, a fraction of casein, and a mixture thereof.

2. The composition according to claim 1, wherein the iron-milk protein complex comprises exogenous iron.

3. The composition according to claim 1, wherein the iron-milk protein complex comprises exogenous phosphorus.

4. The composition according to claim 1, wherein the iron in the iron-milk protein complex is Fe^3+.

5. The composition according to claim 1, wherein the composition in powder form is a nutritional composition.

6. The composition according to claim 1, wherein the iron-milk protein complex is present in an amount comprising 1 to 300 mg of the iron per 100 g of the composition.

7. The composition according to claim 1, wherein the milk protein in the iron-milk protein complex consists of casein.

8. The composition according to claim 1, wherein the milk protein in the iron-milk protein complex is casein, and the iron-milk protein complex consists of the casein and the iron.

9. The composition according to claim 2, wherein a weight ratio of the milk protein to the exogenous iron is between 50:

1 and 19.5;

1.

10. The composition according to claim 3, wherein the exogenous phosphorus comprises orthophosphorus, and a weight ratio of the milk protein to the orthophosphorus is 20:

1 to 8;

1.

11. The composition according to claim 3, wherein the iron-milk protein complex consists of the iron, the milk protein and the exogenous phosphorus.

12. The composition according to claim 1, wherein the iron-milk protein complex comprises the only iron in the composition.

13. The composition according to claim 1, further comprising polyphenols.