SNR improvement and operator-independence using time-varying frame-selection for strain estimation

• US 11,202,618 B2
• Filed: 09/20/2016
• Issued: 12/21/2021
• Est. Priority Date: 09/21/2015
• Status: Active Grant

• Current Assignee: Edan Instruments, Inc.
• Original Assignee: Edan Instruments, Inc.
• Inventors: Srinivasan, Seshadri
• Primary Examiner(s): Hoffa, Angela M
• Assistant Examiner(s): Choi, Younhee
• Application Number:
  US15/271,019
• Publication Number:
  US 20170079619A1
• Time in Patent Office: 1,918 Days
• CPC Class Codes: A61B 8/4427 Device being portable or laptop-like
• CPC Class Codes: A61B 8/485 involving measuring strain or elastic properties
• CPC Class Codes: A61B 8/5215 involving processing of medical diagnostic data
• CPC Class Codes: A61B 8/5269 involving detection or reduction of artifacts for image enhancement algorithms G06T5/00

Abstract

An ultrasound processing system includes an ultrasound interface and processing electronics. The ultrasound interface receives imaging information. The processing electronics are coupled to the ultrasound interface and are configured to utilize the ultrasound imaging information to use time-varying frame selection to estimate strain so that the processing electronics perform the time-varying frame selection by comparing a single frame to a plurality of previous frames and selecting a single comparison set for each frame for strain estimation.

Claims

1. An ultrasound processing system for elastography comprising:

an ultrasound interface connector that receives ultrasound imaging information including a plurality of frames including at least a first frame, a second frame previous to the first frame, and a third frame previous to the first frame; and

processing electronics coupled to the ultrasound interface connector, wherein the processing electronics;

divide each of the plurality of frames into a plurality of sections, wherein each of the plurality of frames is divided into the plurality of sections based on a strain decay at a given depth;

for each particular section of the plurality of sections of the first frame of the plurality of frames;

generate a plurality of comparison sets and corresponding selection values including at least a first comparison set having a corresponding selection value based on the particular section of the first frame of the plurality of frames and the particular section of the second frame of the plurality of frames and a second comparison set having a corresponding selection value based on the particular section of the first frame of the plurality of frames and the particular section of the third frame of the plurality of frames, each selection value including at least one of a displacement or a strain;

select, responsive to generating the plurality of comparison sets, a single comparison set from the plurality of comparison sets based on the corresponding selection values of each of the plurality of comparison sets; and

assign the selection value of the selected single comparison set to the particular section of the first frame; and

generate an image based on the plurality of frames using the selected single comparison set and the assigned selection value for each section of the plurality of sections of the first frame.

2. The ultrasound processing system of claim 1, wherein the processing electronics use multi-frame displacement estimation for comparing frames.

3. The ultrasound processing system of claim 1, wherein each of the corresponding selection values includes a mean strain, and the processing electronics select the selected single comparison set by comparing the mean strain to a desired strain.

4. The ultrasound processing system of claim 1, wherein the processing electronics select the selected single comparison set having a highest signal to noise ratio.

5. The ultrasound processing system of claim 1, wherein the processing electronics normalize the selection value of the selected single comparison set for each section of the plurality of sections for the first frame of the plurality of frames.

6. The ultrasound processing system of claim 1, wherein the processing electronics select the selected single comparison set based on a desired displacement and/or strain.

7. The ultrasound processing system of claim 1, wherein the processing electronics select the selected single comparison set to use based on a weighted system, the weighted system based on a displacement and/or strain average and a desired displacement and/or strain.

8. The ultrasound processing system of claim 1, wherein the processing electronics predict a periodicity of motion.

9. The ultrasound processing system of claim 1, wherein the processing electronics generate a feedback including the selected single comparison set.

10. The ultrasound processing system of claim 9, wherein the processing electronics use the feedback of the selected single comparison set to estimate at least one of a displacement or a strain of at least one previous frame of the plurality of frames.

11. The ultrasound processing system of claim 1, wherein the plurality of frames are divided into the plurality of sections based on depth, wherein the plurality of sections includes a first section corresponding to a first depth and a second section corresponding to a second depth;

the first comparison set has the corresponding selection value based on the first section of the first frame of the plurality of frames and the second section of the second frame of the plurality of frames; and

the second comparison set has the corresponding selection value based on the first section of the first frame of the plurality of frames and the second section of the third frame of the plurality of frames.

12. The ultrasound processing system of claim 1, wherein the generating the plurality of comparison sets and corresponding selection values comprises performing comparisons for all comparison sets and all sections in a designated segment of data;

and after the performing comparisons for all comparison sets and all sections in the designated segment of data, the selecting the single comparison set from the plurality of comparison sets is performed based on previous frame selections.

13. A method of signal to noise ratio improvement in elastography using time-varying frame selection strain estimation, the method comprising:

receiving imaging and displacement and/or strain data including a plurality of frames including at least a first frame, a second frame previous to the first frame, and a third frame previous to the first frame;

dividing each frame of the plurality of frames into a plurality of sections, wherein each frame of the plurality of frames is divided into the plurality of sections based on a strain decay at a given depth;

for each particular section of the plurality of sections for the first frame of the plurality of frames;

generating a plurality of comparison sets and corresponding selection values using the imaging and displacement and/or strain data including at least a first comparison set having a corresponding selection value based on the particular section of the first frame of the plurality of frames and the particular section of the second frame of the plurality of frames and a second comparison set having a corresponding selection value based on particular section of the first frame of the plurality of frames and the particular section of the third frame of the plurality of frames, each selection value including at least one of a displacement or a strain;

selecting, responsive to generating the plurality of comparison sets, a frame comparison set from the plurality of comparison sets based on the corresponding selection values of each of the plurality of comparison sets; and

assigning the selection value of the selected frame comparison set to particular section of the first frame;

generating an image based on the plurality of frames using the selected frame comparison set and the assigned the selection value for each section of the plurality of sections of the first frame, and

displaying the image.

14. The method of claim 13, wherein after a defined period, the selected frame comparison set is used to estimate a final displacement and/or strain through a feedback.

15. The method of claim 14, wherein the estimated final strain is estimated by normalizing the assigned selection value for each section of the plurality of sections of the first frame.

16. The method of claim 13, wherein the selected frame comparison set is selected based on at least one of a mean or a signal to noise ratio (SNR) of the assigned selection value for each section of the plurality of sections of the first frame.

17. The method of claim 13, wherein the plurality of frames are divided into the plurality of sections based on depth, wherein the plurality of sections includes a first section corresponding to a first depth and a second section corresponding to a second depth;

the first comparison set has the corresponding selection value based on the first section of the first frame of the plurality of frames and the second section of the second frame of the plurality of frames; and

the second comparison set has the corresponding selection value based on the first section of the first frame of the plurality of frames and the second section of the third frame of the plurality of frames.

18. The method of claim 13, wherein the generating the plurality of comparison sets and corresponding selection values comprises performing comparisons for all comparison sets and all sections in a designated segment of data;

and after the performing comparisons for all comparison sets and all sections in the designated segment of data, the selecting the frame comparison set from the plurality of comparison sets is performed based on previous frame selections.

19. An ultrasound machine comprising

one or more processors and a memory storing computer-readable instructions that when executed by the one or more processors, cause the one or more processors to:

receive ultrasound returns representative of an ultrasound scene for display including a plurality of frames;

divide each of the plurality of frames into sections based on a strain decay at a given depth;

generate, for each section in a first frame of the plurality of frames, a plurality of comparison sets wherein for each comparison set, the section of the first frame is compared to the corresponding section of a different frame of the plurality of frames;

generate, for each comparison set of each section in the first frame of the plurality of frames, a selection value based on the compared sections of the comparison set;

select, responsive to generating the selection values, a single comparison set from the plurality of comparison sets for each section of the first frame based on the generated selection values of the comparison sets;

generate an elastic image based on the selected single comparison set for each section of the first frame.

20. The ultrasound machine of claim 19, wherein the plurality of frames are divided into sections based on depth including at least a first section corresponding to a first depth and a second section corresponding to a second depth;

the first comparison set has the corresponding selection value based on the first section of the first frame of the plurality of frames and the second section of the second frame of the plurality of frames; and

the second comparison set has the corresponding selection value based on the first section of the first frame of the plurality of frames and the second section of the third frame of the plurality of frames.

21. The ultrasound machine of claim 19, wherein the one or more processors comprise a frame comparator configured to generate the plurality of comparison sets by performing comparisons for all comparison sets and all sections in a designated segment of data;

and after the frame comparator has passed the designated segment, the frame comparator become passive and the one or more processors is configured to select the single comparison set based on previous frame selections.