Systems and methods for deploying a biosensor in conjunction with a prosthesis

• US 20020111543A1
• Filed: 04/12/2002
• Published: 08/15/2002
• Est. Priority Date: 03/10/2000
• Status: Active Grant

• Current Assignee: Remon Medical Technologies Ltd. (Boston Scientific Corporation)
• Original Assignee: Remon Medical Technologies Ltd. (Boston Scientific Corporation)
• Inventors: Penner, Avi, Wolinsky, Lone
• Granted Patent: US 6,743,173 B2
• Time in Patent Office: Days
• US Class Current: 600/309
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: A61B 5/02014 Determining aneurysm
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61B 5/036 by means introduced into body tracts A61B5/032 and A61B5/035 take precedence
• CPC Class Codes: A61B 5/6862 Stents
• CPC Class Codes: A61B 5/6876 Blood vessel
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/89 the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching
• CPC Class Codes: A61F 2250/0002 for data transfer

Abstract

A biosensor for monitoring pressure or other physical parameters at an aneurysm site is mountable to a tubular prosthesis that is expandable between contracted and enlarged conditions. A loop, having the biosensor attached thereto, is securable around the prosthesis. An apparatus is used to deliver the loop to an aneurysm site that includes a catheter having a connector on its distal end for detachably securing the loop thereto. The prosthesis is advanced in a contracted state to the aneurysm, and the apparatus, with the loop connected thereto, is advanced to the aneurysm site. The loop and the prosthesis are positioned coaxially with respect to one another, and the prosthesis is expanded towards its enlarged condition, thereby engaging the loop around the prosthesis and engaging the prosthesis with a wall of the blood vessel at the treatment site.

Claims

1. A method for implanting a biosensor within a body lumen of a patient, comprising:

introducing a tubular prosthesis in a contracted state within the body lumen;

introducing a loop within the body lumen, the loop including a biosensor attached thereto;

positioning the loop and the prosthesis coaxially with respect to one another; and

expanding the prosthesis towards an enlarged condition, thereby engaging the loop around the prosthesis.

2. The method of claim 1, wherein the loop is introduced within the body lumen within a lumen of a delivery apparatus, the loop being detachably secured to the delivery apparatus.

3. The method of claim 2, further comprising deploying the loop from the delivery apparatus before positioning the loop around the prosthesis.

4. The method of claim 3, further comprising releasing the loop from the delivery apparatus after positioning the loop around the prosthesis.

5. The method of claim 4, wherein the loop is released from the delivery device after the prosthesis is expanded towards its enlarged condition.

6. The method of claim 1, wherein the step of introducing the loop comprises:

expanding the loop across a treatment site; and

advancing the prosthesis through the loop upon positioning the loop and prosthesis coaxially with respect to one another.

7. The method of claim 1, wherein the body lumen comprises an aneurysm.

8. The method of claim 7, wherein the biosensor is disposed within an aneurysmal sac at least partially defined by the aneurysm after the prosthesis is expanded to its enlarged condition.

9. The method of claim 1, further comprising the step of engaging the prosthesis with a wall of the blood vessel.

10. An apparatus for delivering a biosensor to a treatment site within a body lumen, comprising:

a catheter having a proximal end and a distal end adapted for introduction into the body lumen;

an attachment loop having a biosensor attached thereto; and

a connector on the catheter for detachably securing the attachment loop to the catheter.

11. The apparatus of claim 10, wherein the connector is on the distal end of the catheter.

12. The apparatus of claim 10, wherein the connector is on a side region of the catheter.

13. The apparatus of claim 10, wherein said connector comprises a wire extending through the catheter.

14. The apparatus of claim 10, wherein said connector comprises a pair of opposing mandibles having a slot therebetween for engaging the loop.

15. The apparatus of claim 13, wherein the attachment loop comprises a ring attached thereto for receiving the wire therethrough.

16. The apparatus of claim 10, further comprising:

a tubular prosthesis expandable between a contracted condition for facilitating introduction into the body lumen, and an enlarged condition; and

a delivery device for directing the prosthesis to the treatment site in its contracted condition.

18. The apparatus of claim 17, further comprising a tubular prosthesis wherein said loop is adapted for coaxial engagement over the tubular prosthesis.

19. The apparatus of claim 18, wherein said tubular prosthesis is expandable between a contracted condition for facilitating introduction into the body lumen, and an enlarged condition for contacting a wall of the body lumen at a treatment site.

20. The apparatus of claim 18, wherein the loop is secured to the tubular prosthesis by friction.

17. An apparatus implantable within a body lumen, said apparatus comprising a loop having a biosensor attached thereto, said loop expandable between a contracted condition and an expanded condition, and said biosensor extending radially outward from the loop.

21. An apparatus for monitoring a physical parameter at an aneurysmal site within a blood vessel lumen comprising:

a tubular prosthesis;

a loop having a size for securing the loop coaxially around the prosthesis; and

a biosensor attached to the loop and extending radially outward from the loop.

22. The apparatus of claim 21, wherein the biosensor is a sensor selected from the group consisting of a pressure sensor, a temperature sensor, a pH sensor, a blood sugar sensor, a blood oxygen sensor, a motion sensor, an acceleration sensor, a force sensor, a strain sensor, an acoustics sensor, a moisture sensor, an osmolarity sensor, a light sensor, a turbidity sensor, a radiation sensor, an electromagnetic field sensor, a chemical sensor, an ionic sensor, and an enzymatic sensor.

23. The apparatus of claim 21, wherein the loop comprises a ring or sleeve formed from a substantially elastic material, the ring or sleeve having a relaxed state having a cross-section smaller than the prosthesis.

24. The apparatus of claim 21, wherein the loop is compressible to facilitate its insertion into a delivery device.