Process and apparatus for utilization of in vivo extracted plasma with tissue engineering devices, bioreactors, artificial organs, and cell therapy applications
First Claim
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1. A method of treating cells, tissues or organs comprising:
- implanting an in vivo plasma separation device within a blood vessel of a patient or donor;
separating blood plasma from whole blood in vivo using said plasma separation device;
directing said plasma from the plasma separation device to a bioreactor; and
exposing said plasma to cells, tissue or organ in said bioreactor.
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Abstract
The present invention is directed to a method of treating cells, tissues or organs using in vivo plasma separation by implanting a plasma separation filter device within a blood vessel of a patient, or allogenic, or xenogenic donor, continuously separating blood plasma from whole blood in vivo, directing the plasma from the plasma separation filter device to a bioreactor, and exposing the plasma to cells, tissue or an organ within the bioreactor utilizing immune separation membranes where necessary.
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Citations
31 Claims
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1. A method of treating cells, tissues or organs comprising:
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implanting an in vivo plasma separation device within a blood vessel of a patient or donor;
separating blood plasma from whole blood in vivo using said plasma separation device;
directing said plasma from the plasma separation device to a bioreactor; and
exposing said plasma to cells, tissue or organ in said bioreactor. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31)
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Specification