Device for verifying the accuracy of a spectral analyzer

• US 20030030798A1
• Filed: 06/28/2002
• Published: 02/13/2003
• Est. Priority Date: 08/31/1999
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: CME Telemetrix, Inc.
• Inventors: Drennan, Paul, Samsoondar, James, Kaushal, Ashwani
• Granted Patent: US 6,614,521 B2
• Time in Patent Office: Days
• US Class Current: 356/243.1
• CPC Class Codes: A61B 2560/0233 Optical standards
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1455 using optical sensors, e.g. spectral photometrical oximeters
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes
• CPC Class Codes: B82Y 15/00 Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
• CPC Class Codes: G01N 21/4785 Standardising light scatter apparatus; Standards therefor
• CPC Class Codes: Y10S 977/904 for medical, immunological, body treatment, or diagnosis
• CPC Class Codes: Y10S 977/926 Topical chemical, e.g. cosmetic or sunscreen
• CPC Class Codes: Y10S 977/954 Of radiant energy
• CPC Class Codes: Y10S 977/958 Of biomolecule property

Abstract

An artificial member that mimics the absorbance spectrum of an animal body part and includes the spectral components of blood analytes is disclosed. The artificial member is made of a light scattering and reflecting material and is configured to be reproducibly received in a measuring receptor that is operatively connected to a non-invasive monitoring device.

Claims

1. An artificial member that mimics the absorbance spectrum of an animal body part and includes the spectral components of blood analytes, the artificial member comprising a container made of a light scattering and reflecting material, the container comprising one or more chambers and having a neck extending from one end thereof, the neck comprising an orifice sealed with a cap, and the artificial member being configured to be reproducibly received in a measuring receptor that is operatively connected to a non-invasive monitoring device.

2. The artificial member of claim 1, further comprising a septum fitting over the orifice and secured by a cap.

3. The artificial member of claim 2, wherein the septum is uniform with the cap.

4. The artificial member of claim 1, wherein the neck further comprises a flange, and the cap is secured about the flange.

5. The artificial member of claim 4, wherein the flange is an annular flange.

6. The artificial member of claim 5, wherein the cap is a crimp cap.

7. The artificial member of claim5, wherein the cap is made of aluminum.

8. The artificial member of claim 1, wherein the light scattering and reflecting material is Teflon®

-PTFE.

9. The artificial member of claim 1, wherein the light scattering and reflecting material is Teflon®

-PTFE containing from about 0.1% to about 25% glass fiber.

10. The artificial member of claim 9, wherein the light scattering and reflecting material is Teflon®

-PTFE containing about 5% glass fiber.

11. The artificial member of claim 1, wherein the body part that is mimicked is a human finger.

12. The artificial member of claim 1, wherein the one or more chambers comprises a single chamber.

13. The artificial member of claim 1, wherein the one or more chambers comprises two chambers.

14. The artificial member of claim 1, wherein the one or more chambers are cylindrical in shape.

15. The artificial member of claim 1, wherein the one or more chambers are filled with an O-cellulose material that mimics the light scattering properties of tissue.

16. The artificial member of claim 1, wherein the one or more chambers are filled with a gel material containing amaranth dye and sodium benzoate and holding light scattering and reflective particles that mimic the light scattering properties of body tissue.

17. The artificial member of claim 16, wherein the reflective particles comprise Teflon®

-PTFE, TiO₂ or polystyrene nanospheres.

18. The artificial member of claim 1, further comprising a stabilizing member extending from the chamber portion to reversibly urge surfaces of the artificial member into contact with the measuring receptor.

19. A method for mimicking the absorbance spectrum of an animal body part that includes the spectral components of blood analytes, the method comprising:

(a) providing an artificial member comprising a container made of a light scattering and reflecting material, the container comprising one or more chambers, and having a neck extending from one end thereof, the neck comprising an orifice sealed with a cap, the artificial member being configured to be reproducibly received in a measuring receptor that is operatively connected to a non-invasive monitoring device;

(b) inserting the artificial member into the measuring receptor;

(c) taking measurements with the monitoring device; and

(d) comparing the measurements obtained in step (c) with those obtained from a body part of a subject, which the artificial member is configured to mimic.

20. The method of claim 19, wherein the artificial member provided in step (a) further comprises a septum fitting over the orifice and being secured by the cap.

21. The method of claim 20, wherein the septum of the artificial member provided in step (a) is uniform with the cap.

22. The method of claim 21, wherein the neck of the artificial member provided in step (a) further comprises a flange, and wherein the cap is secured over the flange.

23. The method of claim 22, wherein the neck flange of the artificial member provided in step (a) is an annular flange.

24. The method of claim 23, wherein the cap of the artificial member provided in step (a) is a crimp cap.

25. The method of claim 24, wherein the cap of the artificial member provided in step (a) is formed of aluminum.

26. The method of claim 19, wherein the light scattering and reflecting material of the artificial member provided in step (a) is Teflon®

-PTFE.

27. The method of claim 19, wherein the light scattering and reflecting material of the artificial member provided in step (a) is Teflon®

-PTFE containing from about 0.1% to about 25% glass fiber.

28. The method of claim 27, wherein the light scattering and reflecting material of the artificial member provided in step (a) is Teflon®

-PTFE containing from about 0.1% to about 5% glass fiber.

29. The method of claim 19, wherein the animal body part being mimicked is a human finger.