Encapsulation of actives in core-shell and gel particles

• US 20030050393A1
• Filed: 12/13/2001
• Published: 03/13/2003
• Est. Priority Date: 12/18/2000
• Status: Active Grant

• Current Assignee: Dow, Inc.
• Original Assignee: Dow, Inc.
• Inventors: Smith, Janet Mary, Lin, Zuchen, Ferritto, Michael Salvatore
• Granted Patent: US 6,774,179 B2
• Time in Patent Office: Days
• US Class Current: 524/837
• CPC Class Codes: A61K 2800/412 Microsized, i.e. having sizes between 0.1 and 100 microns
• CPC Class Codes: A61K 2800/56 Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
• CPC Class Codes: A61K 8/0241 Containing particulates characterized by their shape and/or structure see also A61K8/04, A61K8/11, and A61K8/14, further aspects are classified in A61K2800/40 and subcodes
• CPC Class Codes: A61K 8/042 Gels
• CPC Class Codes: A61K 8/11 Encapsulated compositions
• CPC Class Codes: A61K 8/898 containing nitrogen, e.g. amodimethicone, trimethyl silyl amodimethicone or dimethicone propyl PG-betaine
• CPC Class Codes: A61Q 13/00 Formulations or additives for perfume preparations essential oils or perfumes per se C11B9/00
• CPC Class Codes: A61Q 15/00 Anti-perspirants or body deodorants deodorisation of air A61L9/00
• CPC Class Codes: A61Q 17/04 Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin
• CPC Class Codes: A61Q 5/00 Preparations for care of the hair
• CPC Class Codes: C08J 2383/04 Polysiloxanes
• CPC Class Codes: C08J 3/205 in the presence of a continuous liquid phase
• CPC Class Codes: C08J 3/26 of latex
• CPC Class Codes: C08L 83/08 containing silicon bound to organic groups containing atoms other than carbon, hydrogen and oxygen

Abstract

This invention pertains to silicone core-shell or gel particles that contain active ingredients. The silicone particles are produced by emulsifying and reacting a composition comprising a siloxane have a first reactive group, a crosslinker having a second reactive group, at least one emulsion liquid, a surfactant and an active ingredient. The active ingredient is encapsulated in the silicone particle and are useful in personal care products, textiles, auto care products, and laundry products for the delivery of active ingredients.

Claims

1. A method for producing silicone particles where said method comprises emulsifying and reacting a composition comprising

(I) a siloxane oligomer or polymer having units of

 

where each Y is independently selected from

R′

;

an alkyl group with 1 to 30 C atoms, an aryl group having 6 to 15 carbon atoms, an alkaryl group having 6 to 15 carbon atoms, and an aralkyl group having 6 to 15 carbon atoms;

Z;

a reactive group selected from epoxy-functional groups or chlorohydrin functional groups;

Z′

;

a functional group that reacts with epoxy-functional groups or chlorohydrin functional groups (i.e. amine, hydroxyl);

F;

a functional group other than Z or Z′

, and

O (oxygen radicals);

with the proviso that at least 50 mol % of the Y groups in the siloxane are R′

, and there are at least two Z and/or Z′

groups in the siloxane;

(II) a crosslinker wherein said crosslinker contains Z and/or Z′

groups with the proviso that when Y in siloxane (I) contains Z groups, the crosslinker contains Z′

groups;

when Y in siloxane (I) contains Z′

groups, the crosslinker contains Z groups; and

when Y in siloxane (I) contains Z and Z′

groups, the crosslinker contains Z groups, Z′

groups or both;

(III) at least one emulsion liquid;

(IV) a surfactant; and

(V) and active ingredient.

2. The method as claimed in claim 1 wherein in siloxane (I) there are at least two Z′

groups and the crosslinker (II) contains Z groups.

3. The method as claimed in claim 1 wherein in siloxane (I) there are at least two Z groups and the crosslinker contains (II) Z′

groups.

4. The method as claimed in claim 1 wherein R′

is a methyl group.

8. The method as claimed in claim 2 wherein the Z′

group is an amine group and Z is an epoxy group.

9. The method as claimed in claim 3 wherein Z epoxy group and Z′

is an amine group.

10. The method as claimed in claim 1 wherein siloxane (I) and crosslinker (II) are present in an amount to provide a ratio reactive sites in Z to Z′

in a range of 0.1;

1 to 1.5;

1.

11. The method as claimed in claim 10 wherein the ratio in the range of 0.2:

1 to 0.5;

1.

12. The method as claimed in claim 10 wherein the ratio in the range of 0.25:

1 to 0.35;

1.

13. The method as claimed in claim 1 wherein siloxane (I) and crosslinker (II) are present in an amount so that the silicone particle comprises 0.1 to 80 wt. % of the composition.

14. The method as claimed in claim 1 where the emulsion liquid is water.

15. The method as claimed in claim 14 wherein water comprises 1 to 99.8 wt. % of the composition.

16. The method as claimed in claim 1 wherein the surfactant is present in an amount of 0.1 to 40 wt. % of the composition.

17. The method as claimed in claim 1 wherein the active ingredient is present in an amount of 10 to 50 wt. % of the composition.

18. The method as claimed in claim 1 wherein the active ingredient is a sunscreen.

19. The method as claimed in claim 1 wherein the active ingredient is a fragrance.

20. The method as claimed in claim 1 wherein the active ingredient reacts with the siloxane (I) and/or crosslinker (II).

21. The method as claimed in claim 1 wherein a first mixture comprising (II) and (V) is combined with a second mixture comprising (I), (III) and (IV) the combined mixture is thereafter emulsified and reacted.

22. The method as claimed in claim 1 wherein the reaction is carried out at a temperature in the range of 25°

C. to 150°

C.

23. A silicone particle produced by emulsifying and reacting a composition comprising

(I) a siloxane oligomer or polymer having units of

 

where each Y is independently selected from

R′

;

an alkyl group with 1 to 30 C atoms, an aryl group having 6 to 15 carbon atoms, an alkaryl group having 6 to 15 carbon atoms, and an aralkyl group having 6 to 15 carbon atoms;

Z;

a reactive group selected from epoxy-functional groups or chlorohydrin functional groups;

Z′

;

a functional group that reacts with epoxy-functional groups or chlorohydrin functional groups (i.e. amine, hydroxyl);

F;

a functional group other than Z or Z′

, and

O (oxygen radicals);

with the proviso that at least 50 mol % of the Y groups in the siloxane are R′

, and there are at least two Z and/or Z′

groups in the siloxane;

(II) a crosslinker wherein said crosslinker contains Z and/or Z′

groups with the proviso that when Y in siloxane (I) contains Z groups, the crosslinker contains Z′

groups;

when Y in siloxane (I) contains Z′

groups, the crosslinker contains Z groups; and

when Y in siloxane (I) contains Z and Z′

groups, the crosslinker contains Z group, Z′

groups or both;

(III) at least one emulsion liquid;

(IV) a surfactant; and

(V) and active ingredient.