PLASMA TREATED SURGICAL NEEDLES AND METHODS FOR THEIR MANUFACTURE
First Claim
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1. A method for coating a surgical needle comprising the steps of:
- providing a surgical needle having a surface; and
forming a polymer coating on at least a portion of the surface of the needle by plasma polymerization of a hydrocyclosiloxane monomer of the general formula where R is an aliphatic group and n is an integer from 2 to about 10, preferably 4 to6, whereby the polymer coated needle exhibits reduced penetration force compared to an uncoated needle.
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Abstract
Methods for siliconizing surgical needles include a plasma polymerization coating process.
14 Citations
48 Claims
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1. A method for coating a surgical needle comprising the steps of:
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providing a surgical needle having a surface; and
forming a polymer coating on at least a portion of the surface of the needle by plasma polymerization of a hydrocyclosiloxane monomer of the general formula where R is an aliphatic group and n is an integer from 2 to about 10, preferably 4 to6, whereby the polymer coated needle exhibits reduced penetration force compared to an uncoated needle. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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21. A method for coating a surgical needle comprising the steps of:
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providing a surgical needle having a surface;
subjecting the surface of the needle to a plasma polymerization process wherein a polymer coating is formed on the needle surface from a hydrocyclosiloxane monomer of the general formula where R is an aliphatic group and n is an integer from 2 to about 10, preferably 4 to6;
adding an amine group onto the polymer coating by subjecting the needle to a gas containing a monomer selected from the group consisting essentially of unsaturated N-protected amines, unsaturated N-unprotected amines, N-protected cyclic aliphatic amines, and N-unprotected cyclic aliphatic amines, to produce an amine grafted polymer coating; and
contacting the amine grafted polymer coating with a carbonate-based polyalkylene oxide compound of the formula wherein R1 is selected from an N-benzotriazole group, an N-2-pyrrolidinone group, or a 2-oxypyrimidine group;
R2, R3 and R4 are independently selected alkylene groups of about 2 to about 3 carbon atoms and may be the same or different;
R5 is selected from hydrogen, methyl, a carbonyloxy-N-benzotriazole group, a carbonyloxy-N-2-pyrrolidinone group, and a carbonyl-2-oxypyrimidine group;
a is an integer from 1 to 1000 and each of b and c is an integer from 0 to 1000, where a+b+c is an integer from 3 to 1000 to produce a polyoxyalkylene modified polymer coating. - View Dependent Claims (22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37)
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38. A coated surgical needle comprising:
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a surgical needle having an outer surface; and
a plasma polymerized polymer coating formed on at least a portion of said outer surface of said surgical needle. - View Dependent Claims (39, 40, 41)
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42. A coated surgical needle comprising:
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a surgical needle having an outer surface;
a polymer coating formed on at least a portion of said outer surface of said surgical needle, said polymer coating including a plasma polymerized amine substituted polymer coating having polyoxyalkylene groups bonded thereto. - View Dependent Claims (43, 44, 45)
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46. A surgical needle having reduced penetration force comprising:
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a surgical needle having a polymer coating formed by a plasma polymerization process; and
a silicone-containing coating over at least a portion of the polymer coating, whereby the surgical needle has a penetration force on a fifth pass through tissue that is at least 10% less than the penetration force on a fifth pass through tissue of a needle having the same silicone-containing coating on the same surgical needle having no polymer coating. - View Dependent Claims (47, 48)
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Specification