Ordered adsorbed layers of nano particulate materials on structured nano-laminate templates

• US 20030129087A1
• Filed: 06/11/2002
• Published: 07/10/2003
• Est. Priority Date: 06/13/2001
• Status: Abandoned Application

• Current Assignee: Regents of the University of California (University of California)
• Original Assignee: Regents of the University of California (University of California)
• Inventors: Barbee, Troy W. Jr., Wilson, William D.
• Application Number:
  US10/167,926
• Publication Number:
  US 20030129087A1
• Time in Patent Office: Days
• US Class Current: 422/58
• CPC Class Codes: B82Y 30/00 Nanotechnology for materials or surface science, e.g. nanocomposites
• CPC Class Codes: C30B 23/002 Controlling or regulating
• CPC Class Codes: C30B 23/02 Epitaxial-layer growth
• CPC Class Codes: C30B 29/605 Products containing multiple oriented crystallites, e.g. columnar crystallites
• CPC Class Codes: G01N 25/147 by cristallisation

Abstract

Structural nano-laminate templates to collect and organize atoms, molecules, nano-crystals, colloids, cells, proteins, and spores. The nanostructured materials enables controlled deposition of molecules and nanoparticles, and in many applications, enable attachment of organic or “soft” matter to an inorganic or “hard” substrate. This enables the deposition of proteins onto specific site or into ordered arrays which can facilitate their detection as well as their crystallization. The nano-laminates may be constructed using magnetron sputtering to deposit alternating layers of selected materials, such as amorphous alumina and amorphous silica, on a silicon substrate. The substrate is then sectioned and polished, exposing the cross-sections of the deposited layers, and to which selected proteins, for example, are attached in an ordered manner.

Claims

1. In a sensor, the improvement comprising:

a nano-laminate template,

said nano-laminate having at least one polished, exposed cross-section.

2. The improvement of claim 1, wherein said nano-laminate is composed of material selected from the group consisting of oxide/oxide, oxide/metal, metal/metal, metal/alloy, alloy/oxide, metal/nitride, metal/carbide, nitride/nitride, and carbide/carbide.

3. The improvement of claim 2, additionally including a conducting substrate.

4. The improvement of claim 1, wherein said nano-laminate is composed of alumina-silica.

5. The improvement of claim 4, wherein the alumina-silica nano-laminate has a period in the range of about 1->

200 nm.

6. The improvement of claim 5, wherein said alumina-silica nano-laminate is deposited on a silicon substrate.

7. The improvement of claim 6, wherein the nano-laminate has a thickness of about 5 μ

m, contains about 50 alumina-silica pairs, with periods of about 10 nm.

8. The improvement of claim 1, wherein said nano-laminate is selected from the group consisting of Al₂O₃/ZrO₂, Al₂O₃/Y(ZrO₂), CeO₂/Al₂O₃, Al₂O₃/SiO₂, YZr/Al₂O₃, and Monel 400/SiO₂.

9. The improvement of claim 8, wherein said nano-laminate is composed of 100 nm Al₂O₃ with 100 nm of ZrO₂, Y(ZrO₂), and CeO₂.

10. The improvement of claim 8, wherein said nano-laminate has a cross-section of up to about 200 μ

m.

11. The improvement of claim 8, wherein the Al₂O₃ is amorphous.

12. The improvement of claim 8, wherein each of the ZrO₂ and Y(ZrO₂) is initially amorphous or extremely fine grained, developing a crystalline phase as the layer thickness increases.

13. The improvement of claim 8, wherein the CeO₂ is crystalline.

14. The improvement of claim 8, wherein the Al₂O₃ and ZrO₂ have a zero-point charge value of 9.3 and 7.9, respectively.

15. The improvement of claim 8, wherein the nano-laminate is Al₂O₃/SiO₂ with zero-point charge values of 9.3 and 3 respectively.

16. The improvement of claim 1, wherein the nano-laminate is oxide/metal with the oxide being SiO₂.

17. The improvement of claim 16, wherein said oxide/metal nano-laminate is backed with a conducting substrate that allows an external potential to be applied to the conducting layers.

18. The improvement of claim 1, wherein said nano-laminate is composed of a number of ˜

1 nm gold layer separated by a distance of about 5 nm, and employed as an initiation layer for protein orientation.

19. The improvement of claim 1, wherein said nano-laminate includes individual layer thicknesses of 1 nm to greater than 200 nm.

20. The improvement of claim 1, wherein said nano-laminate has alternating composition cross-sectioned <

1 nm to >

200 nm period multilayers.

21. The improvement of claim 1, wherein said nano-laminate is composed of magnetron sputtered alumina/silica, ceria/alumina, zirconia/alumina, and ythria-stabilized zironia/alumina.

24. The improvement of claim 8, wherein said nano-laminate is composed of YZr—

Al₂O₃ having a cross-section selected from the group consisting of 10 nm, 20 nm, 100 nm, 200 nm, and 400 nm.

25. The improvement of claim 8, wherein said nano-laminate is composed of Monel 400/SiO₂.

22. The improvement of claim 22, wherein said nano-laminate is composed of different periods of alternating materials.

23. A means for collecting and organizing proteins including a nano-laminate cross-section for ordered absorption of proteins.