SELECTED ESSENTIAL AMINO ACID SUPPLEMENTATION OF DIETARY PROTEINS TO LOWER URINARY UREA AND PEAK GLUCOSE LEVELS

• US 20030139465A1
• Filed: 01/23/2002
• Published: 07/24/2003
• Est. Priority Date: 01/23/2002
• Status: Active Grant

• Current Assignee: Charles Ignatius Jarowski
• Original Assignee: Charles Ignatius Jarowski
• Inventors: Jarowski, Charles Ignatius
• Granted Patent: US 6,602,909 B1
• Time in Patent Office: Days
• US Class Current: 514/419
• CPC Class Codes: A23L 33/175 Amino acids
• CPC Class Codes: A23V 2002/00 Food compositions, function of food ingredients or processes for food or foodstuffs
• CPC Class Codes: A23V 2250/063 Lysine
• CPC Class Codes: A23V 2250/0632 Methionine
• CPC Class Codes: A23V 2250/065 Tryptophan
• CPC Class Codes: A23V 2250/0654 Valine
• CPC Class Codes: A61K 31/198 Alpha-amino acids, e.g. alanine or edetic acid [EDTA] betaine A61K31/205; proline A61K31/401; tryptophan A61K31/405; histidine A61K31/4172; peptides not degraded to individual amino acids A61K38/00
• CPC Class Codes: A61K 31/405 Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin

Abstract

Depending upon the quantity of protein being consumed, one or more unit doses of a blend consisting of L-Tryptophan (80 mgs), L-Methionine (90 mgs), L-Valine (103 mgs) and L-Lysine Monohydrochloride (128 mgs), added as a dietary supplement, will improve the efficiency of amino acid utilization and thereby lower urinary urea excretion and control peak post-prandial blood glucose levels. The levels of supplementation are derived by taking into consideration the average human fasting plasma concentrations of essential amino acids and L-Tyrosine and L-Cystine.

Claims

1. Dietary supplementation with a blend of L-Tryptophan, L-Methionine, L-Valine and L-Lysine Monohydrochloride in such quantities that the relative proportions of at least the first three limiting essential amino acids in the supplemented ration conform adequately to the respective proportions found in the average fasting blood plasma of humans improves amino acid utilization by lowering their conversion to urea.

2. Peak post-prandial blood glucose levels are lowered when easily hydrolyzed proteins are supplemented with a blend of L-Tryptophan, L-Methionine, L-Valine and L-Lysine Monohydrochloride in such quantities that the relative proportions of at least the first three limiting essential amino acids in the supplemented ration conform adequately to the respective proportions found in the average fasting human blood plasma.