High viscosity antibacterials for cannulae
First Claim
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1. The method which comprises:
- applying an antibacterial fluid to a tubular medical cannula for access to a patient, said fluid comprising an antibacterial formulation having a viscosity of about 5,000 to 80,000 cp, and inserting the cannula into the patient or a medical device communicating with the patient.
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Abstract
An antibacterial fluid may be applied to a tubular medical cannula for access to a patient. The fluid comprises a metabolizable antibacterial formulation having a viscosity of at least about 5,000 cp. The cannula may then be inserted into the patient with an increased lubricity for a reduction of pain, while at the same time, unlike silicones, materials do not readily accumulate in the patient. The tubular medical cannula may be a rigid, hollow needle, sharp or blunt, a spike, or a flexible catheter. Also, the viscous antibacterial fluid may be used to lock a catheter or other cannula while implanted in the patient, for storage purposes.
54 Citations
38 Claims
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1. The method which comprises:
- applying an antibacterial fluid to a tubular medical cannula for access to a patient, said fluid comprising an antibacterial formulation having a viscosity of about 5,000 to 80,000 cp, and inserting the cannula into the patient or a medical device communicating with the patient.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
- 10. An antibacterial formulation which comprises a relatively low viscosity antibacterial agent mixed with sufficient viscosity increasing agent to provide a viscosity of about 5,000 to 80,000 cp to the formulation.
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23. The method which comprises placing an antibacterial fluid in a cannula tract extending through the skin of a patient and inwardly therefrom, said method comprising;
- inserting a cannula coated with said fluid into said cannula tract; and
passing flushing fluid through the cannula to exit said cannula at an inner portion of said tract and to cause said flushing fluid to flow outwardly through said tract so that some of said fluid exits around the cannula through the skin;
said antibacterial fluid having a viscosity of about 5,000 to 80,000 cp. - View Dependent Claims (24, 25, 26, 27, 28)
- inserting a cannula coated with said fluid into said cannula tract; and
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29. The method which comprises:
- placing a fluid into a lumen of a catheter installed in a patient to “
lock”
the catheter, to reduce the flow of body fluids into the catheter lumen as the catheter resides in the patient, said fluid having a viscosity of about 5,000 to 80,000 cp. - View Dependent Claims (30, 31, 32)
- placing a fluid into a lumen of a catheter installed in a patient to “
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33. The method which comprises placing a fluid on the outer surface of a medical cannula, said fluid comprising an antibacterial agent and having a viscosity of about 5,000 to 80,000 cp, and thereafter inserting the cannula through the skin of the patient or into a sterile receptacle.
- 34. The method which comprises placing a portion of a fluid, which comprises an antibacterial agent and has a viscosity of about 5,000 cp to 80,000 cp, on the skin of a patient to form a fluid layer on the skin, and thereafter passing a medical cannula through the fluid layer on the skin and through the skin of the patient.
- 36. An aqueous solution of an antithrombogenic agent, present in a concentration effective to suppress blood clotting, said solution also comprising a viscosity increasing agent and having a viscosity of 5,000 to 80,000 cp.
Specification