Apparatus and methods for treating congestive heart disease

• US 20040097900A1
• Filed: 07/03/2003
• Published: 05/20/2004
• Est. Priority Date: 01/11/1999
• Status: Active Grant

• Current Assignee: AngioDynamics, Inc.
• Original Assignee: Ascher Schmulewitz, Gad Keren
• Inventors: Keren, Gad, Schmulewitz, Ascher
• Granted Patent: US 7,341,570 B2
• Time in Patent Office: Days
• US Class Current: 604/500
• CPC Class Codes: A61B 17/12013 for use in minimally invasive surgery, e.g. endoscopic surgery
• CPC Class Codes: A61B 17/12036 partial occlusion
• CPC Class Codes: A61B 17/12045 double occlusion, e.g. during anastomosis
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/12136 Balloons
• CPC Class Codes: A61B 17/1219 expandable in contact with liquids
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2017/00898 expandable upon contact with fluid
• CPC Class Codes: A61B 2017/061 hollow or tubular suture extending inside a hollow needle A61B2017/06052; hollow sutures A61B2017/06185
• CPC Class Codes: A61B 2017/22054 with two balloons
• CPC Class Codes: A61F 2002/068 Modifying the blood flow model, e.g. by diffuser or deflector
• CPC Class Codes: A61M 1/3613 Reperfusion, e.g. of the coronary vessels, e.g. retroperfusion
• CPC Class Codes: A61M 1/3623 Means for actively controlling temperature of blood
• CPC Class Codes: A61M 1/3653 Interfaces between patient blood circulation and extra-corporal blood circuit
• CPC Class Codes: A61M 1/3659 Cannulae pertaining to extracorporeal circulation
• CPC Class Codes: A61M 2025/1052 for temporarily occluding a vessel for isolating a sector
• CPC Class Codes: A61M 2210/1082 Kidney
• CPC Class Codes: A61M 2210/125 Heart
• CPC Class Codes: A61M 25/00 Catheters; Hollow probes dilators A61M29/00; peritoneal catheters A61M1/285; tracheal tubes A61M16/04; for drainage A61M27/00; for uterus, vagina or rectum A61M31/00 ; for measuring or testing A61B; materials for catheters A61L29/00
• CPC Class Codes: A61M 25/0075 Valve means
• CPC Class Codes: A61M 25/10 : Balloon catheters A61M25/0125 takes precedence; embolectomy A61B17/22032; retractors A61B17/02; inflatable balloons for placing stents or stent-grafts A61F2/958 ; stomach balloons for treatment of obesity A61F5/0003; oesophagal tubes A61J15/00
• CPC Class Codes: A61M 25/1011 : Multiple balloon catheters
• CPC Class Codes: A61M 27/002 : Implant devices for drainage of body fluids from one part of the body to another intraocular A61F9/00781; middle ear A61F11/202
• CPC Class Codes: A61M 60/113 : in other functional devices, e.g. dialysers or heart-lung machines
• CPC Class Codes: A61M 60/13 : by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
• CPC Class Codes: A61M 60/148 : in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
• CPC Class Codes: A61M 60/232 : Centrifugal pumps
• CPC Class Codes: A61M 60/258 : Piston pumps
• CPC Class Codes: A61M 60/279 : Peristaltic pumps, e.g. roller pumps
• CPC Class Codes: A61M 60/33 : of kidneys
• CPC Class Codes: A61M 60/38 : Blood oxygenation
• CPC Class Codes: A61M 60/414 : transmitted by a rotating cable, e.g. for blood pumps mounted on a catheter
• CPC Class Codes: A61M 60/833 : Occluders for preventing backflow
• CPC Class Codes: A61M 60/867 : using position detection during deployment, e.g. for blood pumps mounted on and driven through a catheter

Abstract

Methods and apparatus are provided for treating congestive heart failure using a catheter having an inlet end configured for placement in the source of arterial blood such as the aorta, left ventricle or a femoral artery, and an outlet end having at least one conduit configured to be placed in the renal arteries. The catheter includes a lumen through which blood passes from the aorta or left ventricle directly to the renal artery, means for engaging the first conduit with renal artery. The means for engaging also may reduce backflow of blood into the abdominal aorta. The catheter preferably is configured to permit percutaneous, transluminal implantation. Methods of using and implanting the catheter are also provided.

Claims

1. Apparatus for locally perfusing one or more kidneys comprising:

a catheter having an inlet end, an outlet end, and a lumen, the inlet end configured for placement in a source of arterial blood, the outlet end having at least a first conduit configured for insertion into a first renal artery; and

means for engaging the first conduit within the first renal artery.

2. The apparatus of claim 1 wherein the inlet end is configured for placement in a patient'"'"'s left ventricle.

3. The apparatus of claim 1 wherein the outlet end further comprises a second conduit configured for placement in a second renal artery.

4. The apparatus of claim 1 further comprising a drug infusion device.

5. The apparatus of claim 1 further comprising a blood pump.

6. The apparatus of claim 1 further comprising a one-way valve that permits blood to flow only from the inlet end to the outlet end.

7. The apparatus of claim 1 wherein the means for engaging comprises an occluder formed from a self-expanding water-swellable material.

8. The apparatus of claim 1 wherein the means for engaging comprises an inflatable member.

9. The apparatus of claim 1 wherein the means for engaging comprises a plurality of ribs or barbs disposed on an exterior surface of the first conduit.

10. The apparatus of claim 1 further comprising a radio-opaque marker band disposed on the first conduit.

11. Apparatus for use in treating congestive heart failure comprising:

a flexible catheter having an inlet end, an outlet end, and a lumen, the inlet end configured for insertion into a source of arterial blood, the outlet end including a first conduit configured for insertion into a patient'"'"'s renal artery; and

means for engaging an interior surface of a renal artery disposed on the first conduit to retain the first conduit in the patient'"'"'s renal artery.

12. The apparatus of claim 11 further comprising a drug infusion device.

13. The apparatus. of claim 11 further comprising a blood pump.

14. The apparatus of claim 11 further comprising a one-way valve that permits blood to flow only from the inlet end to the outlet end.

15. The apparatus of claim 11 wherein the means for engaging comprises a self-expanding water-swellable material.

16. The apparatus of claim 11 wherein the means for engaging comprises an inflatable member.

17. The apparatus of claim 11 further comprising a radio-opaque marker band disposed on the first conduit.

18. A method of locally perfusing one or more kidneys comprising:

providing a flexible catheter having an inlet end, a lumen, and an outlet end including a first conduit;

advancing the catheter percutaneously and transluminally along a guidewire to dispose the inlet end in a source of arterial blood;

inserting the first conduit into a patient'"'"'s renal artery; and

engaging the first conduit within the patient'"'"'s renal artery.

19. The method of claim 18 wherein providing a catheter comprises providing a catheter including a drug infusion device, the method further comprising:

periodically activating the drug infusion device to infuse a drug into blood flowing through the lumen.

20. The method of claim 18 wherein providing a catheter comprises providing a catheter including a blood pump, the method further comprising:

actuating the blood pump to increase a rate of blood flow through the lumen.