Novel human kinases and polynucleotides encoding the same

• US 20040180416A1
• Filed: 03/18/2004
• Published: 09/16/2004
• Est. Priority Date: 04/06/2001
• Status: Active Grant

• Current Assignee: Brian Mathur, Carl Johan Friddle, Turner C. Alexander Jr
• Original Assignee: Brian Mathur, Carl Johan Friddle, Turner C. Alexander Jr
• Inventors: Friddle, Carl Johan, Mathur, Brian, Turner, C. Alexander Jr.
• Granted Patent: US 6,919,192 B2
• Time in Patent Office: Days
• US Class Current: 435/183
• CPC Class Codes: C12N 9/1205 Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases

Abstract

Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.

Claims

1. An isolated nucleic acid molecule comprising a nucleotide sequence encoding the amino acid sequence shown in SEQ ID NO:

2, SEQ ID NO;

4 or SEQ ID NO;

6.

2. The isolated nucleic acid molecule of claim 1, comprising a nucleotide sequence encoding the amino acid sequence shown in SEQ ID NO:

2.

3. The isolated nucleic acid molecule of claim 1, comprising a nucleotide sequence encoding the amino acid sequence shown in SEQ ID NO:

4.

4. The isolated nucleic acid molecule of claim 1, comprising a nucleotide sequence encoding the amino acid sequence shown in SEQ ID NO:

6.

5. A substantially isolated protein having the kinase activity of the protein shown in SEQ ID NO:

2, SEQ ID NO;

4 or SEQ ID NO;

6, which is encoded by a nucleotide sequence that hybridizes to SEQ ID NO;

1, SEQ ID NO;

3 or SEQ ID NO;

5 under highly stringent conditions.