Wearable, portable sonic applicator for inducing the release of bioactive compounds from internal organs
First Claim
1. A method for inducing the release of active biopharmaceutical compositions from various organs, glands or other bio-structures within the body of an individual, comprising applying ultrasound through a transducer device which is affixed to the exterior of the patient'"'"'s body and worn by the patient during the day, said transducer device controlled by a portable, programmable ultrasonic regulator device, which itself is worn by the individual wherein said ultrasound is applied at an intensity and for a time period effective to enable movement of a therapeutic quantity of said active pharmaceutical composition from the target organ, glands or other bio-structures for the purpose of effecting regulated, and timed drug delivery of said of active biopharmaceutical composition(s) to the individual.
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Abstract
The invention is a portable device for transmitting acoustical energy from an ultrasonic generator, through the exterior surface of the skin of a patient, for the purpose of increasing the release of biofunctional compounds from a targeted organ for treatment of disease or injury. In particular the invention is a means to cause the release of insulin from the patient'"'"'s pancreas, to enhance the treatment of diabetes. The portable device is programmable as to acoustic frequency, intensity, and time thereby regulating the amount of insulin, which can be induced to be released in response to the sonic transmission from the patient'"'"'s pancreas. The device can be programmed for steady sonic transmission or for pulsed transmissions as needed. The device is primarily aimed at Type-2 diabetics, who produce insulin internally but not necessarily in amounts or at times needed for effective biofunctionality. In such instance the invention, through the use of sonic transmissions, may be used to artificially induce the proper release of insulin from a diabetic pancreas, with or without the use of accompanying medication.
33 Citations
17 Claims
- 1. A method for inducing the release of active biopharmaceutical compositions from various organs, glands or other bio-structures within the body of an individual, comprising applying ultrasound through a transducer device which is affixed to the exterior of the patient'"'"'s body and worn by the patient during the day, said transducer device controlled by a portable, programmable ultrasonic regulator device, which itself is worn by the individual wherein said ultrasound is applied at an intensity and for a time period effective to enable movement of a therapeutic quantity of said active pharmaceutical composition from the target organ, glands or other bio-structures for the purpose of effecting regulated, and timed drug delivery of said of active biopharmaceutical composition(s) to the individual.
- 15. A method for inducing the release of insulin from within the pancreas of an individual, comprising applying ultrasound through a transducer device which is affixed to the exterior of the patient'"'"'s body and worn by the patient during the day, said transducer device controlled by a portable, programmable ultrasonic regulator device, which itself is worn by the individual wherein said ultrasound is applied at an intensity and for a time period effective to enable movement of a therapeutic quantity of insulin from the pancreas for the purpose of effecting regulated, and timed drug delivery of said insulin to the individual.
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17. A method for inducing the release of active biopharmaceutical compositions from various structures within the body of an individual, comprising applying ultrasound through a transducer device which is implanted within the patient'"'"'s body and worn by the patient during the day, said transducer device controlled by a portable, programmable ultrasonic regulator device, which itself is either implanted or worn by the individual on the exterior of the body, wherein said ultrasound is applied at an intensity and for a time period effective to enable movement of a therapeutic quantity of said active pharmaceutical composition from the target organ, for the purpose of effecting regulated, and timed drug delivery of said of active biopharmaceutical composition(s) to the individual.
Specification