Medicament dispenser

• US 20050022806A1
• Filed: 05/14/2002
• Published: 02/03/2005
• Est. Priority Date: 06/11/2001
• Status: Abandoned Application

• Current Assignee: Glaxo Group Limited (Glaxosmithkline Holdings Ltd.)
• Original Assignee: Glaxo Group Limited (Glaxosmithkline Holdings Ltd.)
• Inventors: Walker, Richard Ian, Jones, Anthony Patrick, Davies, Michael Birsha, Beaumont, Gary Robert
• Application Number:
  US10/479,568
• Publication Number:
  US 20050022806A1
• Time in Patent Office: Days
• US Class Current: 128/200.140
• CPC Class Codes: A61M 15/0065 Inhalators with dosage or measuring devices A61M15/0028 takes precedence; dosage devices incorporated in aerosol cans B65D83/52
• CPC Class Codes: A61M 15/0071 having a display or indicator
• CPC Class Codes: A61M 15/008 Electronic counters
• CPC Class Codes: A61M 15/0083 Timers
• CPC Class Codes: A61M 15/009 using medicine packages with incorporated spraying means, e.g. aerosol cans pocket atomiser of the injector type A61M11/08
• CPC Class Codes: A61M 2005/31588 electrically driven
• CPC Class Codes: A61M 2016/0024 with an on-off output signal, e.g. from a switch
• CPC Class Codes: A61M 2205/0266 Shape memory materials
• CPC Class Codes: A61M 2205/0288 Electro-rheological or magneto-rheological materials
• CPC Class Codes: A61M 2205/3306 Optical measuring means
• CPC Class Codes: A61M 2205/3553 remote, e.g. between patient's home and doctor's office
• CPC Class Codes: A61M 2205/3569 sublocal, e.g. between console and disposable
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2205/6054 Magnetic identification systems
• CPC Class Codes: A61M 2205/8206 battery-operated
• CPC Class Codes: A61M 2205/8212 with means or measures taken for minimising energy consumption
• CPC Class Codes: A61M 2205/825 using mechanical generation of electricity, e.g. hand cranked generators
• CPC Class Codes: A61M 5/20 Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically A61M5/142 , A61M5/46 take precedence; hypodermic projectiles F42B12/54
• CPC Class Codes: A61M 5/31546 Electrically operated dose setting, e.g. input via touch screen or plus/minus buttons

Abstract

There is provided a medicament dispenser comprising a housing; a medicament container having a dispensing mechanism; a container seat for receipt of the container; an anchor station on the housing or connecting therewith; and drive means capable of moving the container seat relative to the anchor station to actuate the dispensing mechanism. The drive means is responsive to the application of non-mechanical energy thereto. The medicament dispenser further comprises adjusting means adapted to enable medicament containers of varying sizes to be received by the housing.

Claims

1. A medicament dispenser comprising a housing;

a medicament container having a dispensing mechanism;

a container seat for receipt of the container;

an anchor station on the housing or connecting therewith; and

drive means capable of moving the container seat relative to the anchor station to actuate the dispensing mechanism, said drive means being responsive to the application of non-mechanical energy thereto, wherein the medicament dispenser further comprises adjusting means adapted to enable medicament containers of varying sizes to be received by the housing.

5. A medicament dispenser according to claim 1, wherein the adjusting means comprises variable engaging means.

6. A medicament dispenser according to claim 5, wherein said the variable engaging means comprises a first engager located on a first part of the medicament dispenser and a second engager located on a second part of the medicament dispenser, wherein the first and second engager are engageable with the medicament container.

7. A medicament dispenser according to claim 5, wherein the adjusting means comprises a clutch and drive plate mechanism, which interconnects with a carriage shaft which houses the medicament container.

8. A medicament dispenser according to claim 5, wherein the adjusting means comprises a rack and wheel mechanism.

9. A medicament dispenser according to claim 5, wherein the adjusting means comprises a flexible bag containing a viscous fluid, suitably located in the base of the housing.

10. A medicament dispenser according to claim 5, wherein the adjusting means comprises a drive wedge mechanism.

11. A medicament dispenser according to claim 1, wherein the dispensing mechanism is selected from the group consisting of a valve, pump or plunger mechanism.

12. A medicament dispenser according to claim 1, wherein the drive means comprises a motor.

13. A medicament dispenser according to claim 1, wherein the drive means comprises a coupling, which deforms, or undergoes a phase transition in response to the application of non-mechanical energy thereto.

14. A medicament dispenser according to claim 13, wherein the coupling comprises a shape memory alloy.

15. A medicament dispenser according to claim 14, wherein the shape memory alloy is a nickel-titanium alloy.

16. A medicament dispenser according to claim 1, wherein the drive means additionally comprises gear means to gear up the torque provided thereby.

17. A medicament dispenser according to claim 16, wherein said gear comprises a gear element selected from the group consisting of cam gears, screw drives, levers, crank shafts, pulleys and hydraulic gears.

18. A medicament dispenser according to claim 1, additionally comprising decoupling means adapted to enable the medicament container to return to a non-dispensing position independent of the drive means.

19. A medicament dispenser according to claim 18, wherein said decoupling means comprises a cam in contact either directly or indirectly with the medicament container and a coupling mechanism extending from the cam to a fixed point on the medicament dispenser.

20. A medicament dispenser according to claim 18, wherein the decoupling means comprising a beam, rotatably hinged at its centre point, said beam being movable between a first non-dispensing position through a dispensing position to a second non-dispensing position.

21. A medicament dispenser according to claim 18, wherein the decoupling means comprising a top crown and a push crown, the two crowns engaging with each other.

22. A medicament dispenser according to claim 1, additionally comprising drive-assisting means adapted to provide a mechanical advantage to the drive mechanism.

23. A medicament dispenser according to claim 22, wherein said drive-assisting means comprises one or more levers and one or more pivot points.

24. A medicament dispenser according to claim 22, wherein the drive-assisting means comprises a rotatable cylinder comprising a downwardly spiralling guide track and a guide arm fixed to the medicament container, wherein the guide arm is locatable within the guide track and the drive means connects to one end of the rotatable cylinder.

25. A medicament dispenser according to claim 22, wherein the drive-assisting means comprises a bowed beam connected at each end to a coupling mechanism, the beam having a notch removed in the lower surface thereof.

26. A medicament dispenser according to claim 22, wherein the drive-assisting means acts such as to change the work profile of the drive mechanism.

27. A medicament dispenser according to claim 1, wherein the medicament dispenser has a use configuration and a storage configuration such that the medicament dispenser in its storage configuration is smaller than when in the use configuration.

28. A medicament dispenser according to claim 27, wherein the housing comprises a telescopic arrangement.

29. A medicament dispenser according to claim 1, wherein the medicament container is an aerosol container.

30. A medicament dispenser according to claim 29, wherein, the aerosol container comprises a suspension of a medicament in a propellant.

31. A medicament dispenser according to claim 30, wherein the medicament is selected from the group consisting of albuterol, salmeterol, fluticasone propionate, fluticasone furoate, beclomethasone dipropionate, salts or solvates thereof and any mixtures thereof.

32. A medicament dispenser according claim 1, wherein actuation of the drive mechanism is responsive to a patient-actuable trigger comprising a sensor which senses the breath of a patient.

38. A kit of parts comprising a medicament dispenser according to any of claims 1 to 32 in the form of a cartridge;

and a housing shaped for receipt of said cartridge.

2. A medicament dispenser comprising a medicament container having a dispensing mechanism;

a container seat for receipt of the container;

a dispenser seat for receipt of the dispensing mechanism; and

drive means capable of moving the container seat relative to the dispenser seat to actuate the dispensing mechanism, said drive means being responsive to the application of non-mechanical energy thereto, wherein the medicament dispenser further comprises adjusting means adapted to enable medicament containers of varying sizes to be received by the housing.

3. A medicament dispenser comprising a housing;

a medicament container for containing medicament for release;

an aerosol container having a dispensing mechanism;

a container seat for receipt of the aerosol container;

an anchor station on the housing or connecting therewith; and

drive means capable of moving the container seat relative to the anchor station to actuate the dispensing mechanism to energise released medicament, said drive means being responsive to the application of non-mechanical energy thereto, wherein the medicament dispenser further comprises adjusting means adapted to enable aerosol containers of varying sizes to be received by the housing.

4. A medicament dispenser comprising a medicament container for containing medicament for release;

an aerosol container having a dispensing mechanism;

a container seat for receipt of the container;

a dispenser seat for receipt of the dispensing mechanism; and

drive means capable of moving the container seat relative to the dispenser seat to actuate the dispensing mechanism to energise released medicament, said drive means being responsive to the application of non-mechanical energy thereto, wherein the medicament dispenser further comprises adjusting means adapted to enable aerosol containers of varying sizes to be received by the housing.

33. An actuator for a medicament container having a dispensing mechanism comprising a container seat for receipt of the medicament container;

a dispenser seat for receipt of the dispensing mechanism; and

drive means capable of moving the container seat relative to the dispenser seat to actuate the dispensing mechanism, said drive means being responsive to the application of non-mechanical energy thereto, wherein the medicament dispenser further comprises adjusting means adapted to enable medicament containers of varying sizes to be received by the housing.

37. A laboratory test apparatus comprising at least one actuator according to any of claims 33 to 36 and a mounting for said at least one actuator.

39. A kit of parts comprising an actuator according to any of claims 33 to 36 and, receivable by said actuator, a medicament container having a dispensing mechanism.

34. An actuator for a medicament container having a dispensing mechanism comprising a housing;

within said housing, a container seat for receipt of the medicament container;

on the housing or connecting therewith, an anchor station; and

drive means capable of moving the container seat relative to the anchor station to actuate the dispensing mechanism, said drive means being responsive to the application of non-mechanical energy thereto, wherein the medicament dispenser further comprises adjusting means adapted to enable medicament containers of varying sizes to be received by the housing.

35. An actuator for a medicament dispenser having a medicament container and separately an aerosol container having a dispensing mechanism comprising a housing, shaped for receipt of said medicament container for containing medicament for release;

within said housing, a container seat for receipt of said aerosol container having a dispensing mechanism;

an anchor station on the housing or connecting therewith; and

drive means capable of moving the container seat relative to the anchor station to actuate the dispensing mechanism to energise released medicament, said drive means being responsive to the application of non-mechanical energy thereto, wherein the medicament dispenser further comprises adjusting means adapted to enable aerosol containers of varying sizes to be received by the housing.

36. An actuator for a medicament dispenser having a medicament container and separately an aerosol container having a dispensing mechanism comprising a housing, shaped for receipt of said medicament container for containing medicament for release;

an aerosol container having a dispensing mechanism;

a container seat for receipt of said aerosol container having a dispensing mechanism;

a dispenser seat for receipt of the dispensing mechanism; and

drive means capable of moving the container seat relative to the dispenser seat to actuate the dispensing mechanism to energise released medicament, said drive means being responsive to the application of non-mechanical energy thereto, wherein the medicament dispenser further comprises adjusting means adapted to enable aerosol containers of varying sizes to be received by the housing.