Expandable cardiac harness for treating congestive heart failure
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Abstract
A cardiac harness for treating congestive heart failure is disclosed. The harness applies elastic, compressive reinforcement on the left ventricle to reduce deleterious wall tension and to resist shape change of the ventricle during the mechanical cardiac cycle. Rather than imposing a dimension beyond which the heart cannot expand, the harness provides no hard limit over the range of diastolic expansion of the ventricle. Instead, the harness follows the contour of the heart throughout diastole and continuously exerts gentle resistance to stretch. Also disclosed is a method of delivering the cardiac harness to the heart minimally invasively.
211 Citations
223 Claims
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1-53. -53. (canceled)
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54. A method for attenuating remodeling of a heart, comprising:
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mounting a cardiac harness on the heart, the cardiac harness applying a compressive force on the heart during at least a portion of a cardiac cycle;
decreasing wall stress on the left ventricle by action of the compressive force of the cardiac harness; and
attenuating expansion or remodeling of the heart as the cardiac harness applies compressive force on the heart during the at least a portion of the cardiac cycle. - View Dependent Claims (55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87)
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88. A method for attenuating remodeling of a heart, comprising:
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after a patient experiences an acute myocardial infarction;
mounting a cardiac harness on the heart, the cardiac harness applying a compressive force on the heart during at least a portion of a cardiac cycle;
decreasing wall stress on the left ventricle by action of the compressive force of the cardiac harness; and
attenuating expansion or remodeling of the heart as the cardiac harness applies compressive force on the heart during the at least a portion of the cardiac cycle. - View Dependent Claims (89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120)
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121. A method for attenuating remodeling of a heart, comprising:
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mounting a cardiac harness on the heart, the cardiac harness having elastic hinges for applying a compressive force on the heart during at least a portion of a cardiac cycle;
decreasing wall stress on the left ventricle by action of the compressive force of the elastic hinges; and
attenuating expansion or remodeling of the heart as the elastic hinges of the cardiac harness apply compressive force on the heart during the at least a portion of the cardiac cycle. - View Dependent Claims (122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150, 151, 152, 153, 154)
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155. A method for preventing remodeling of a heart, comprising:
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mounting a cardiac harness on the heart, the cardiac harness applying a compressive force on the heart during at least a portion of a cardiac cycle;
decreasing wall stress on the left ventricle by action of the compressive force of the cardiac harness; and
preventing expansion or remodeling of the heart as the cardiac harness applies compressive force on the heart during the at least a portion of the cardiac cycle. - View Dependent Claims (156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189)
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190. A method for attenuating remodeling of a heart, comprising:
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mounting a cardiac harness on the heart, the cardiac harness applying a compressive force on the heart during at least a portion of a cardiac cycle;
decreasing wall stress on the left ventricle and the right ventricle by action of the compressive force of the cardiac harness; and
attenuating expansion or remodeling of the heart as the cardiac harness applies compressive force on the heart during the at least a portion of the cardiac cycle. - View Dependent Claims (191, 192, 193, 194, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223)
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Specification