Chemically modified small molecules

  • US 20050136031A1
  • Filed: 12/16/2004
  • Published: 06/23/2005
  • Est. Priority Date: 12/16/2003
  • Status: Active Grant
First Claim
Patent Images

1. A composition comprising monodisperse or bimodal conjugates, each conjugate comprised of a moiety derived from a small molecule drug covalently attached by a stable linkage to a water-soluble oligomer, wherein said conjugate exhibits a reduced biological membrane crossing rate as compared to the biological membrane crossing rate of the small molecule drug not attached to the water-soluble oligomer.

View all claims
    ×
    ×

    Thank you for your feedback

    ×
    ×