Intravascular devices and fibrosis-inducing agents
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Abstract
Intravascular devices (e.g., stents, stent grafts, covered stents, aneurysm coils, embolic agents and drug delivery catheters and balloons) are used in combination with fibrosing agents in order to induce fibrosis that may otherwise not occur when the implant is placed within an animal or to promote fibrosis betweent the devices and the host tissues. Compositions and methods are described for use in the treatment of aneurysms and unstable arterial (vulnerable) plaque.
275 Citations
1480 Claims
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1-1360. -1360. (canceled)
- 1361. A method for reducing perigraft leakage associated with stent graft delivery in a patient, comprising delivering a device to a patient in need thereof, wherein the device comprises i) a stent graft and ii) a fibrosing agent or a composition comprising a fibrosing agent, wherein the agent induces fibrosis.
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1385. (canceled)
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1386. (canceled)
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1392. (canceled)
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1419. (canceled)
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1424. (canceled)
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1444-1452. -1452. (canceled)
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1461. (canceled)
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1476. (canceled)
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1478. (canceled)
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1480-1738. -1738. (canceled)
Specification