Apparatus and method for delivering therapeutic and diagnostic agents
First Claim
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1. A method for delivering a selected diagnostic or therapeutic agent to a target site within a selected body tissue having a surface, comprising the steps of:
- (a) providing a drug-delivery tool comprising (i) an accessing device having distal and proximal ends, an inner lumen extending therebetween, a drug-delivery reservoir, and a user-control structure;
(ii) a tissue-penetrating implement carried on the distal end of the accessing device for axial movement in and out of the lumen, wherein the implement comprises a tip for penetrating the body tissue, and is operatively connected to the user-control structure; and
(iii) at least a first transducer located at the distal end of the accessing device;
(b) placing the distal end of the accessing device into contact with a selected body tissue surface;
(c) manipulating the orientation of the accessing device to a desired orientation, based on at least one signal from the first transducer;
(d) selectively actuating the tissue-penetrating implement to penetrate the selected body tissue surface.
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Abstract
A drug-delivery tool and method for delivering a diagnostic or therapeutic agent to a target site within a selected body tissue, such as the myocardium of the heart, is disclosed. The drug-delivery tool generally includes an accessing device having a tissue-penetrating implement in its distal-end region, and elements for delivering a selected agent into a cavity formed by the implement. Methods of use are also described.
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15 Claims
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1. A method for delivering a selected diagnostic or therapeutic agent to a target site within a selected body tissue having a surface, comprising the steps of:
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(a) providing a drug-delivery tool comprising (i) an accessing device having distal and proximal ends, an inner lumen extending therebetween, a drug-delivery reservoir, and a user-control structure;
(ii) a tissue-penetrating implement carried on the distal end of the accessing device for axial movement in and out of the lumen, wherein the implement comprises a tip for penetrating the body tissue, and is operatively connected to the user-control structure; and
(iii) at least a first transducer located at the distal end of the accessing device;
(b) placing the distal end of the accessing device into contact with a selected body tissue surface;
(c) manipulating the orientation of the accessing device to a desired orientation, based on at least one signal from the first transducer;
(d) selectively actuating the tissue-penetrating implement to penetrate the selected body tissue surface. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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Specification