Automatic infusion system based on an adaptive patient model

  • US 20050171503A1
  • Filed: 03/24/2003
  • Published: 08/04/2005
  • Est. Priority Date: 03/22/2002
  • Status: Active Grant
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First Claim
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1. An apparatus comprising a sensor to produce a signal indicative of the glycemia levels in a person, a programmable actuator adapted to deliver a blood glucose regulator to said person and a control system adapted to regulate the administration level of said blood glucose regulator, wherein a model-based predictive controller based on a dynamic patient model predicts the future response of the process output to the control input as a function of time and compensates effects of external disturbance on a patient'"'"'s glycemia by adjusting the administration rate of the blood glucose regulator to achieve a status of normoglycemia in said person, which is a critically ill patient or a patient subjected to condition of changing insulin resistance.

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