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Implantable biosensor and methods of use thereof

  • US 20050177035A1
  • Filed: 12/16/2004
  • Published: 08/11/2005
  • Est. Priority Date: 12/18/2003
  • Status: Active Grant
First Claim
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1. A sensor, comprising a) an oxygen transport region comprising a first reversible oxygen binding protein, an oxygen permeable first surface in communication with an external environment, and an oxygen permeable second surface which is impermeable to target analyte;

  • b) a target analyte reaction region in communication with the oxygen transport region at the oxygen permeable second surface, wherein the target analyte reaction region comprises a target analyte oxidase enzyme, and a target analyte-permeable surface; and

    c) a sensing region comprising at least one detector probe in communication with the target analyte reaction region.

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