Invasive appliance

• US 20050177071A1
• Filed: 08/29/2003
• Published: 08/11/2005
• Est. Priority Date: 09/05/2002
• Status: Abandoned Application

• Current Assignee: Matsushita Electric Industrial Company Limited (Panasonic Holdings Corporation)
• Original Assignee: Matsushita Electric Industrial Company Limited (Panasonic Holdings Corporation)
• Inventors: Nakayama, Hiroshi, Hiratsuka, Atsunori, Emoto, Fumiaki
• Application Number:
  US10/516,253
• Publication Number:
  US 20050177071A1
• Time in Patent Office: Days
• US Class Current: 600/583
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150068 by tissue compression, e.g. with specially designed surface of device contacting the skin area to be pierced
• CPC Class Codes: A61B 5/150076 by heating
• CPC Class Codes: A61B 5/150083 by vibration, e.g. ultrasound
• CPC Class Codes: A61B 5/150091 by electricity
• CPC Class Codes: A61B 5/150114 by tissue compression, e.g. with specially designed surface of device contacting the skin area to be pierced
• CPC Class Codes: A61B 5/150122 by heating
• CPC Class Codes: A61B 5/150129 by cooling
• CPC Class Codes: A61B 5/150137 by vibration enhancing collection by vibration A61B5/150175
• CPC Class Codes: A61B 5/150389 Hollow piercing elements, e.g. canulas, needles, for piercing the skin
• CPC Class Codes: A61B 5/150412 Pointed piercing elements, e.g. needles, lancets for piercing the skin blade-like piercing elements A61B5/150442
• CPC Class Codes: A61B 5/150442 Blade-like piercing elements, e.g. blades, cutters, knives, for cutting the skin
• CPC Class Codes: A61B 5/150503 Single-ended needles hollow piercing element tip design A61B5/150396, needle sets for catheters A61M25/06, needles for bringing media into the body A61M5/32
• CPC Class Codes: A61B 5/150977 Arrays of piercing elements for simultaneous piercing
• CPC Class Codes: A61B 5/15107 Piercing being assisted by a triggering mechanism
• CPC Class Codes: A61B 5/15117 comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap
• CPC Class Codes: A61B 5/15136 by use of radiation, e.g. laser
• CPC Class Codes: A61M 5/422 Desensitising skin

Abstract

An invasive apparatus for obtaining an in vivo fluid is provided wherein the invasive apparatus includes a different stimulus applying portion for applying a stimulus different from a stimulus applied by an invasive portion to an organism in a leading end area other than a hole through which the invasive portion exits. The invasive portion is a hollow tube, knife, needle or laser beam, and the different stimulus is a mechanical stimulus. A recessed portion and/or raised portion is formed in the area other than the hole, and the different stimulus applying portion is the recessed portion and/or raised portion. The different stimulus is given by the recessed portion and/or raised portion.

Claims

1. An invasive apparatus of obtaining an in vivo fluid,

wherein the invasive apparatus comprises a different stimulus applying portion of applying a stimulus different from a stimulus applied by an invasive portion to an organism in a leading end area other than a hole through which said invasive portion exits,

said different stimulus applying portion applies a discontinuous stimulus to said surface of the organism, and

after said discontinuous stimulus is applied, said invasive portion invades the surface of said organism.

2. The invasive apparatus according to claim 1, wherein said different stimulus is a mechanical stimulus, electric stimulus, optical stimulus or change in temperature.

3. The invasive apparatus according to claim 2, wherein said different stimulus is a mechanical stimulus,

a recessed portion and/or a raised portion is formed in the area other than said hole,

said different stimulus applying portion is said recessed portion and/or raised portion, and

said different stimulus is given by the recessed portion and/or raised portion.

4. The invasive apparatus according to claim 3, wherein said recessed portion and/or raised portion is at a distance of from at least 1 mm to 20 mm from an area in which said invasive portion contacts the surface of the organism.

5. The invasive apparatus according to claim 4, wherein said surface of the organism is a finger tip, and

said recessed portion and/or raised portion is at a distance of from at least 1 mm to 10 mm from an area in which said invasive portion contacts said finger tip.

6. The invasive apparatus according to claim 5, wherein the invasive apparatus is a lancet apparatus of collecting blood.

7. The invasive apparatus of claim 1, wherein the in vivo fluid is obtained from the depth of 3 mm or less under the skin.

8. The invasive apparatus of claim 1, wherein the different stimulus applying portion is detachable.

9. The invasive apparatus of claim 1, wherein the invasive portion is a hollow tube, knife, needle or laser beam.

10. The invasive apparatus of claim 1, wherein the different stimulus is given continuously or intermittently.

11. The invasive apparatus of claim 1, wherein the different stimulus is given before the invasive portion contacts the surface of the organism.

12. The invasive apparatus of claim 3, wherein the raised portion has a protrusive portion of 0.1 mm or greater.

13. The invasive apparatus of claim 3, wherein the angle at which the raised portion contacts the surface of the organism is 5 degrees or greater.

14. The invasive apparatus of claim 3, wherein the recessed portion and/or raised portion are situated continuously or discontinuously on the outer periphery of the area in which the invasive portion contacts the surface of the organism.

15. The invasive apparatus of claim 3, wherein the recessed portion and/or raised portion are constituted by a rolling body rolling on the surface of the organism.

16. The invasive apparatus of claim 15, wherein the center of gravity of the rolling body is decentered with respect to the center of rotation of the rolling body.

17. The invasive apparatus of claim 3, wherein the recessed portion and/or raised portion are constituted by a vibration body giving vibrations on the surface of the organism.

18. The invasive apparatus of claim 17, wherein the vibration body produces vibrations by a magnetic coil or piezoelectric element.

19. The invasive apparatus of claim 17, wherein the amplitude and/or the frequency of the vibration body are variable.

20. The invasive apparatus of claim 3, wherein a pressure applied to the surface of the organism by the recessed portion and/or raised portion is at least 1 kgf/cm².

21. The invasive apparatus of claim 3, wherein the load application speed of a mechanical stimulus given to the surface of the organism by the recessed portion and/or raised portion is 0.1 Kgf/sec·

cm².

22. The invasive apparatus of claim 3, wherein a time point 0.1 to 5 seconds before invasion by the invasive portion is a point of maximum load application of a mechanical stimulus given to the surface of the organism by the recessed portion and/or raised portion.

23. The invasive apparatus of claim 3, the recessed portion and/or raised portion being constituted by at least a first raised portion and a second raised portion,

wherein the different stimulus is given by sandwiching the surface of the organism between the first raised portion and the second raised portion.

24. The invasive apparatus of claim 1, further comprising a sealed air body,

wherein air is encapsulated in the sealed air body, whereby the surface of the organism is pressed against the different stimulus applying portion of the leading end portion.

25. The invasive apparatus of claim 1, comprising:

organism insertion guiding means of inserting the organism; and

organism holding means of holding the organism,

wherein the organism holding means holds down the organism from the side opposite to the area in which the invasive portion contacts the organism, whereby the organism is pressed against the different stimulus applying portion.

26. An in vivo fluid measuring apparatus comprising:

the invasive apparatus claim 1;

fluid transporting means of transporting an in vivo fluid obtained by invasion by the invasive apparatus; and

a measurement unit,

wherein the measurement unit analyzes the collected in vivo fluid.

27. An invasive method of obtaining an in vivo fluid,

wherein a stimulus different from a stimulus by invasion means is given to an area near the position of the invasion.