Polymer gel containing hyaluronic acid and collagen, and its use in joints
First Claim
1. A formulation comprising polymer gel to treat TMJ disorders.
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Accused Products
Abstract
Formulations and methods for treating joints, such as temporomandibular joint disorders, osteoarthritis of the knee, hip and other types of inflammatory joint diseases. The method involves identifying specific matrix metalloproteinases (MMPs) that may be responsible for degrading the soft tissues of the joint in question, identifying the specific component of the joint the MMP(s) are targeting, and injecting a polymer gel with the component the MMP(s) seek to destroy, thus preserving the joint and allowing time to heal. These formulations typically require a mixture of glycosoaminoglycans and collagen proteins. One formulation in particular includes both hyaluronic acid and at least type I collagen.
9 Citations
10 Claims
- 1. A formulation comprising polymer gel to treat TMJ disorders.
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8. A method for treating joint pain, in which inflammatory cytokines are present in the joint at elevated levels, comprising:
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identifying one or more inflammatory cytokines present in the joint at elevated levels;
determining one or more resulting matrix metalloproteinase (MMP) enzymes present in the joint;
formulating a polymer gel comprising one or more substrates that said MMP enzymes are active against; and
placing the polymer gel into the joint. - View Dependent Claims (9, 10)
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Specification