Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy
First Claim
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1. An apparatus for noninvasive measurement of an analyte property using spectroscopy, comprising:
- a sample module;
that is positioned proximate to a sample site during collection of a sample spectrum;
a base module, physically separated from said sample module, said base module and said sample module each comprising a wireless communication system for communication there between; and
a source located in said sample module;
said base module comprising means for any of generating said analyte property using said spectrum and recording said analyte property generated from said sample spectrum.
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Abstract
The invention involves the monitoring of a biological parameter through a compact analyzer. The preferred apparatus is a spectrometer based system that is attached continuously or semi-continuously to a human subject and collects spectral measurements that are used to determine a biological parameter in the sampled tissue. The preferred target analyte is glucose. The preferred analyzer is a near-IR based glucose analyzer for determining the glucose concentration in the body.
244 Citations
29 Claims
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1. An apparatus for noninvasive measurement of an analyte property using spectroscopy, comprising:
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a sample module;
that is positioned proximate to a sample site during collection of a sample spectrum;
a base module, physically separated from said sample module, said base module and said sample module each comprising a wireless communication system for communication there between; and
a source located in said sample module;
said base module comprising means for any of generating said analyte property using said spectrum and recording said analyte property generated from said sample spectrum. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28)
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29. A method for noninvasive measurement of an analyte property using near-infrared spectroscopy, comprising the steps of:
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providing an analyzer for collecting a near-infrared spectrum of a human tissue sample site; and
estimating said analyte property through application of a multivariate calibration model on said spectrum;
wherein the step of providing said analyzer comprises the steps of;
providing a base module and a sample module that is positioned proximate a sample site during collection of a sample spectrum, and;
that is physically separated from said base module, said base module and said sample module each comprise a wireless communication system for communication there between; and
providing a source located in said sample module;
said base module either of generating said analyte property using said spectrum and recording said analyte property generated from said sample spectrum.
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Specification