Implantable, tissue conforming drug delivery device
First Claim
1. A drug delivery device for implantation into a patient comprising:
- at least one device element which comprises a substrate having a plurality of discrete reservoirs disposed therein, said reservoirs containing drug molecules and a degradable matrix material which controls in vivo release of the drug molecules from the reservoirs, wherein the drug delivery device is adapted to conform to a curved bone tissue surface.
1 Assignment
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Accused Products
Abstract
A drug delivery device for implantation into a patient is provided that includes at least one device element which comprises a substrate having a plurality of discrete reservoirs disposed therein, said reservoirs containing drug molecules and a degradable matrix material which controls in vivo release of the drug molecules from the reservoirs, wherein the drug delivery device is adapted to conform to a curved bone tissue surface. In one embodiment, the substrate is flexible and conforms to a bone tissue surface. In another embodiment, the device has two or more device elements attached to or integral with a flexible supporting layer.
154 Citations
22 Claims
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1. A drug delivery device for implantation into a patient comprising:
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at least one device element which comprises a substrate having a plurality of discrete reservoirs disposed therein, said reservoirs containing drug molecules and a degradable matrix material which controls in vivo release of the drug molecules from the reservoirs, wherein the drug delivery device is adapted to conform to a curved bone tissue surface. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. A drug delivery device for implantation into a patient comprising:
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two or more device elements which each comprise a substrate having a plurality of discrete reservoirs disposed therein, said reservoirs containing therapeutic or prophylactic molecules and a degradable matrix material which controls in vivo release of the therapeutic or prophylactic molecules from the reservoirs, wherein the two or more device elements are flexibly connected together by tethers or hinges. - View Dependent Claims (21, 22)
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Specification