Microjet devices and methods for drug delivery
First Claim
1. A fluid delivery system, comprising:
- a reservoir;
a delivery actuator;
at least one delivery nozzle having an exit orifice with a diameter between about 1 μ
m and about 500 μ
m; and
wherein the delivery actuator is configured to deliver a predetermined quantity of a fluid contained in the reservoir through the at least one delivery nozzle at a pre-determined velocity.
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Accused Products
Abstract
A fluid delivery system includes a reservoir, a delivery actuator, and at least one delivery nozzle of a microjet having an exit orifice with a diameter between about 1 μm and about 500 μm. The delivery actuator may be configured to deliver a quantity of fluid contained in the reservoir into tissue of an individual through the nozzle or nozzles at a pre-determined velocity, and to desired depths. The quantity of fluid may contain one or more therapeutic agents, such as medications, drugs, bio-reactive agents, etc. The delivery actuator may also be configured to repeatedly deliver a quantity of the fluid contained in the reservoir through the at least one delivery nozzle at pre-determined intervals.
143 Citations
26 Claims
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1. A fluid delivery system, comprising:
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a reservoir;
a delivery actuator;
at least one delivery nozzle having an exit orifice with a diameter between about 1 μ
m and about 500 μ
m; and
wherein the delivery actuator is configured to deliver a predetermined quantity of a fluid contained in the reservoir through the at least one delivery nozzle at a pre-determined velocity. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. A method of fluid delivery, comprising:
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providing a fluid delivery device, wherein the fluid delivery device includes at least one microjet having a nozzle with a diameter between about 1 μ
m and about 500 μ
m;
determining a desired penetration depth in a target region of an individual, wherein the penetration depth is less than 3 cm;
locating the fluid delivery device in contact with or adjacent to the target region;
controlling delivery of a fluid through the nozzle of the at least one microjet at a velocity required to deliver the fluid to about the determined penetration depth. - View Dependent Claims (23, 24, 25, 26)
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Specification