Method, apparatus and system for characterizing sleep
First Claim
1. A method of determining a Slow-Wave-Sleep (SWS) period and a Non-SWS (NSWS) period from signals of electrical activity recorded of a chest of a sleeping subject, the signals being measured over a plurality of epochs, the method comprising:
- extracting a series of cardiac R-R intervals from the signals and obtaining a time-frequency decomposition from said series of cardiac R-R intervals; and
using said time-frequency decomposition to determine the SWS period;
thereby determining the SWS period and the NSWS period of the sleeping subject.
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Accused Products
Abstract
A method of determining sleep stages from signals of electrical activity recorded of a chest of a sleeping subject, the signals being measured over a plurality of epochs. The method comprising: (a) extracting a series of cardiac R-R intervals from the signals and obtaining a time-frequency decomposition from the series of cardiac R-R intervals; (b) using the time-frequency decomposition to determine at least one Slow-Wave-Sleep (SWS) period and at least one Non-SWS (NSWS) period; (c) from the at least one NSWS period, determining at least one sleep-onset (SO) period and a plurality of non-sleep periods; (d) extracting a plurality of electromyogram (EMG) parameters from a portion of the signals, the portion corresponds to a NSWS period other than the at least one SO period and other than the plurality of non-sleep period; (e) using the plurality of EMG parameters to determine at least one REM period thereby also to obtain also at least one light-sleep (LS) period defined as a NSWS period other than the SO periods, other than the non-sleep periods and other than the REM periods; thereby determining the sleep stages of the sleeping subject.
73 Citations
342 Claims
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1. A method of determining a Slow-Wave-Sleep (SWS) period and a Non-SWS (NSWS) period from signals of electrical activity recorded of a chest of a sleeping subject, the signals being measured over a plurality of epochs, the method comprising:
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extracting a series of cardiac R-R intervals from the signals and obtaining a time-frequency decomposition from said series of cardiac R-R intervals; and
using said time-frequency decomposition to determine the SWS period;
thereby determining the SWS period and the NSWS period of the sleeping subject. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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21. A method of determining a Rapid-Eye-Movement (REM) sleep and a Non-REM (NREM) sleep from signals of electrical activity recorded of a chest of a sleeping subject, the signals being measured over a plurality of epochs, the method comprising:
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extracting a plurality of electromyogram (EMG) parameters from the signals; and
using said plurality of EMG parameters to determine at least one REM period;
thereby determining the REM sleep and the NREM sleep of the sleeping subject. - View Dependent Claims (22, 23, 24, 25, 26, 27)
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28. A method of determining a Rapid-Eye-Movement (REM) sleep and a Non-REM (NREM) sleep from signals of electrical activity recorded of a chest of a sleeping subject, the signals being measured over a plurality of epochs, the method comprising:
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extracting a series of cardiac R-R intervals from the signals;
constructing a Poincare plot of said series of cardiac R-R intervals; and
using said Poincare plot to determine the REM sleep and the NREM sleep of the sleeping subject. - View Dependent Claims (29, 30, 31, 32, 33, 34)
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35. A method of determining sleep stages from signals of electrical activity recorded of a chest of a sleeping subject, the signals being measured over a plurality of epochs, the method comprising:
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extracting a series of cardiac R-R intervals from the signals and obtaining a time-frequency decomposition from said series of cardiac R-R intervals;
using said time-frequency decomposition to determine at least one Slow-Wave-Sleep (SWS) period and at least one Non-SWS (NSWS) period;
from said at least one NSWS period, determining at least one sleep-onset (SO) period and a plurality of non-sleep periods;
extracting a plurality of electromyogram (EMG) parameters from a portion of the signals, said portion corresponds to a NSWS period other than said at least one SO period and other than said plurality of non-sleep period;
using said plurality of EMG parameters to determine at least one REM period, thereby obtaining also at least one light-sleep (LS) period defined as a NSWS period other than said at least one SO period, other than said plurality of non-sleep periods and other than said at least one REM period;
thereby determining the sleep stages of the sleeping subject. - View Dependent Claims (36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80)
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81. A method of determining a body position or a change in the body position from signals of electrical activity recorded of a chest of a sleeping subject, the signals being characterized by QRS complexes, the method comprising:
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extracting R-wave durations from the QRS complexes, thereby obtaining an R-wave duration (RWD) function; and
using said RWD function to determine the body position or the change in the body position of the sleeping subject. - View Dependent Claims (82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95)
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96. A method of characterizing a sleep of a sleeping subject, the method comprising:
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calculating at least one autonomic balance index (ABI), each corresponding to a different sleep stage of the sleeping subject and being calculated using a weight of said sleep stage and at least one power parameter; and
using said at least one ABI for characterizing the sleep of the sleeping subject. - View Dependent Claims (97, 98, 99, 100, 101, 102, 103, 104, 105, 106)
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107. A method of determining a sleep apnea from signals of electrical activity recorded of a chest of a sleeping subject, the signals being measured over a plurality of epochs, the method comprising:
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(a) extracting a series of cardiac R-R intervals from the signals;
(b) determining awakening periods of the sleeping subject and excluding cardiac R-R intervals corresponding to said awakening periods from said series of cardiac R-R intervals;
(c) obtaining a power spectrum from said series of cardiac R-R intervals; and
(d) using said power spectrum to determine the sleep apnea of the sleeping subject. - View Dependent Claims (108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126)
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127. An apparatus for determining a Slow-Wave-Sleep (SWS) period and a Non-SWS (NSWS) period from signals of electrical activity recorded of a chest of a sleeping subject, the signals being measured over a plurality of epochs, the apparatus comprising:
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an R-R extractor for extracting a series of cardiac R-R intervals from the signals;
a decomposer for obtaining a time-frequency decomposition from said series of cardiac R-R intervals; and
an SWS determinator, for determining the SWS period using said time-frequency decomposition;
thereby to determine the SWS period and the NSWS period of the sleeping subject. - View Dependent Claims (128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 139, 140, 141)
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142. An apparatus for determining a Rapid-Eye-Movement (REM) sleep and a Non-REM (NREM) sleep from signals of electrical activity recorded of a chest of a sleeping subject, the signals being measured over a plurality of epochs, the apparatus comprising:
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an electromyogram (EMG) extractor for extracting a plurality of EMG parameters from the signals; and
a REM determinator for using said plurality of EMG parameters to determine the REM sleep and the NREM sleep of the sleeping subject. - View Dependent Claims (143, 144, 145, 146, 147, 148)
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149. An apparatus for determining a Rapid-Eye-Movement (REM) sleep and a Non-REM (NREM) sleep from signals of electrical activity recorded of a chest of a sleeping subject, the signals being measured over a plurality of epochs, the apparatus comprising:
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an R-R extractor, for extracting a series of cardiac R-R intervals from the signals;
a plotter, for constructing a Poincare plot of said series of cardiac R-R intervals; and
a REM determinator, for using said Poincare plot to determine the REM sleep and the NREM sleep of the sleeping subject. - View Dependent Claims (150, 151, 152, 153, 154, 155)
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156. An apparatus for determining sleep stages from signals of electrical activity recorded of a chest of a sleeping subject, the signals being measured over a plurality of epochs, the apparatus comprising:
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a R-R extractor for extracting a series of cardiac R-R intervals from the signals;
a decomposer, for obtaining a time-frequency decomposition from said series of cardiac R-R intervals;
a Slow-Wave-Sleep (SWS) determinator for using said time-frequency decomposition to determine at least one SWS period and at least one Non-SWS (NSWS) period;
a sleep-onset (SO) determinator for determining at least one SO period onset period from said at least one NSWS period;
a non-sleep determinator for determining plurality of non-sleep periods from said at least one NSWS period;
an electromyogram (EMG) extractor, for extracting a plurality of EMG parameters from a portion of the signals, said portion corresponds to a NSWS period other than said at least one SO period and other than said plurality of non-sleep periods;
a Rapid-Eye-Movement (REM) determinator for using said plurality of EMG parameters to determine at least one REM period, thereby to obtain also at least one LS period defined as a NSWS period other than said at least one SO period, other than said plurality of non-sleep periods and other than said at least one REM period;
thereby to determine the sleep stages of the sleeping subject. - View Dependent Claims (157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 193, 194, 195)
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196. A system for determining a Slow-Wave-Sleep (SWS) period and a Non-SWS (NSWS) period of a sleeping subject, the system comprising:
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an apparatus for providing signals of electrical activity of a chest of the sleeping subject, measured over a plurality of epochs;
an R-R extractor for extracting a series of cardiac R-R intervals from the signals;
a decomposer for obtaining a time-frequency decomposition from said series of cardiac R-R intervals; and
an SWS determinator, for determining the SWS period using said time-frequency decomposition;
thereby to determine the SWS period and the NSWS period of the sleeping subject. - View Dependent Claims (197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215)
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216. A system for determining a Rapid-Eye-Movement (REM) sleep and a Non-REM (NREM) sleep of a sleeping subject, the system comprising:
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an apparatus for providing signals of electrical activity of a chest of the sleeping subject, measured over a plurality of epochs;
an electromyogram (EMG) extractor for extracting a plurality of EMG parameters from the signals; and
a REM determinator for using said plurality of EMG parameters to determine the REM sleep and the NREM sleep of the sleeping subject. - View Dependent Claims (217, 218, 219, 220, 221, 222, 223, 224, 225, 226, 227)
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228. A system for determining a Rapid-Eye-Movement (REM) sleep and a Non-REM (NREM) sleep of a sleeping subject, the system comprising:
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an apparatus for providing signals of electrical activity of a chest of the sleeping subject, measured over a plurality of epochs;
an R-R extractor, for extracting a series of cardiac R-R intervals from the signals;
a plotter, for constructing a Poincare plot of said series of cardiac R-R intervals; and
a REM determinator, for using said Poincare plot to determine the REM sleep and the NREM sleep of the sleeping subject. - View Dependent Claims (229, 230, 231, 232, 233, 234, 235, 236, 237, 238, 239)
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240. A system for determining sleep stages of a sleeping subject, the system comprising:
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an apparatus for providing signals of electrical activity of a chest of the sleeping subject, measured over a plurality of epochs;
an R-R extractor for extracting a series of cardiac R-R intervals from the signals;
a decomposer, for obtaining a time-frequency decomposition from said series of cardiac R-R intervals;
a Slow-Wave-Sleep (SWS) determinator for using said time-frequency decomposition to determine at least one SWS period and at least one Non-SWS (NSWS) period;
a sleep-onset (SO) determinator for determining at least one SO period onset period from said at least one NSWS period;
a non-sleep determinator for determining a plurality of non-sleep periods from said at least one NSWS period;
an electromyogram (EMG) extractor, for extracting a plurality of EMG parameters from a portion of the signals, said portion corresponds to a NSWS period other than said at least one SO period and other than said plurality of non-sleep period;
a Rapid-Eye-Movement (REM) determinator for using said plurality of EMG parameters to determine at least one REM period, thereby to obtain also at least one LS period defined as a NSWS period other than said at least one SO period, other than said plurality of non-sleep periods and other than said at least one REM period;
thereby to determine the sleep stages of the sleeping subject. - View Dependent Claims (241, 242, 243, 244, 245, 246, 247, 248, 249, 250, 251, 252, 253, 254, 255, 256, 257, 258, 259, 260, 261, 262, 263, 264, 265, 266, 267, 268, 269, 270, 271, 272, 273, 274, 275, 276, 277, 278, 279, 280, 281)
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282. An apparatus for determining a body position or a change in the body position from signals of electrical activity recorded of a chest of a sleeping subject, the signals being QRS complexes, the apparatus comprising:
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an R-wave duration (RWD) extractor for extracting R-wave durations from the QRS complexes, thereby to obtain an R-wave duration function a body position determinator for determining the body position or the change in the body position of the sleeping subject using said RWD function. - View Dependent Claims (283, 284, 285, 286, 287, 288, 289, 290, 291, 292)
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293. An apparatus of characterizing a sleep of a sleeping subject, the apparatus comprising:
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an autonomic balance index (ABI) calculator, for calculating at least one ABI, each corresponding to a different sleep stage of the sleeping subject, said ABI calculator is operable to calculated said ABI using a weight of said sleep stage and at least one power parameter; and
a sleep characterizer for characterizing the sleep of the sleeping subject using said at least one ABI. - View Dependent Claims (294, 295, 296, 297, 298, 299, 300, 301, 302, 303)
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304. An apparatus for determining a sleep apnea from signals of electrical activity recorded of a chest of a sleeping subject, the signals being measured over a plurality of epochs, the apparatus comprising:
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an R-R extractor for extracting a series of cardiac R-R intervals from the signals;
a non-sleep determinator for determining awakening periods of the sleeping subject and excluding cardiac R-R intervals corresponding to said awakening periods from said series of cardiac R-R intervals;
a decomposer for calculating a power spectrum from said series of cardiac R-R intervals; and
a sleep apnea determinator for using said power spectrum and determining the sleep apnea of the sleeping subject. - View Dependent Claims (305, 306, 307, 308, 309, 310, 311, 312, 313, 314, 315, 316, 317)
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318. A system for determining a body position or a change in the body position of a sleeping subject, the system comprising:
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an apparatus for providing signals of electrical activity of a chest of the sleeping subject, characterized by QRS complexes;
an R-wave duration (RWD) extractor for extracting R-wave durations from the QRS complexes, thereby to obtain an R-wave duration function a body position determinator for determining the body position or the change in the body position of the sleeping subject using said RWD function. - View Dependent Claims (319, 320, 321, 322, 323, 324, 325, 326, 327, 328)
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329. A system for determining a sleep apnea of a sleeping subject, the system comprising:
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an apparatus for providing signals of electrical activity of a chest of the sleeping subject, measured over a plurality of epochs;
an R-R extractor for extracting a series of cardiac R-R intervals from the signals;
a non-sleep determinator for determining awakening periods of the sleeping subject and excluding cardiac R-R intervals corresponding to said awakening periods from said series of cardiac R-R intervals;
a decomposer for calculating a power spectrum from said series of cardiac R-R intervals; and
a sleep apnea determinator for using said power spectrum and determining the sleep apnea of the sleeping subject. - View Dependent Claims (330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342)
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Specification