Methods and materials for canine breed identification
First Claim
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1. A method for determining the contributions of canid populations to a canid genome, comprising:
- (a) obtaining the identity of one or both alleles in a test canid genome for each of a set of markers; and
(b) determining the contributions of canid populations to the test canid genome by comparing the alleles in the test canid genome to a database comprising canid population profiles, wherein each canid population profile comprises genotype information for the set of markers in the canid population.
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Abstract
In one aspect, the invention provides methods for determining the contributions of canid populations to a canid genome. The methods comprise the steps of: (a) obtaining the identity of one or both alleles in a test canid genome for each of a set of markers; and (b) determining the contributions of canid populations to the test canid genome by comparing the alleles in the test canid genome to a database comprising canid population profiles, wherein each canid population profile comprises genotype information for the set of markers in the canid populations.
25 Citations
37 Claims
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1. A method for determining the contributions of canid populations to a canid genome, comprising:
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(a) obtaining the identity of one or both alleles in a test canid genome for each of a set of markers; and
(b) determining the contributions of canid populations to the test canid genome by comparing the alleles in the test canid genome to a database comprising canid population profiles, wherein each canid population profile comprises genotype information for the set of markers in the canid population. - View Dependent Claims (2, 3, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34)
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4. The method of claim 4, wherein the microsatellite markers comprise at least 5 of the microsatellite markers set forth in Table 1.
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35. A method for defining one or more canid populations, comprising:
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(a) for each of a set of canid genomes, obtaining the identity of one or both alleles for each of a set of markers; and
(b) defining one or more canid populations by determining the likelihood that one or more members of the set of canid genomes define distinct canid populations characterized by a set of allele frequencies for each marker using statistical modeling.
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36. A computer-readable medium comprising a data structure stored thereon for use in distinguishing canid populations, the data structure comprising:
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(a) a marker field, which is capable of storing the name of a marker or of an allele of the marker; and
(b) a genotype information field, which is capable of storing genotype information for the marker in a canid population, wherein a record comprises an instantiation of the marker field and an instantiation of the genotype information field and a set of records represents a canid population profile.
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37. A computer readable medium comprising stored thereon:
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(a) a data structure stored thereon for use in distinguishing canid populations, the data structure comprising;
(i) a marker field, which is capable of storing the name of a marker or of an allele of the marker; and
(ii) a genotype information field, which is capable of storing genotype information for the marker in a canid population, wherein a record comprises an instantiation of the marker field and an instantiation of the genotype information field and a set of records represents a canid population profile; and
(b) computer-executable instructions for implementing a method for determining the contributions of canid populations to a canid genome, comprising;
(i) obtaining the identity of one or both alleles in a test canid genome for each of a set of markers; and
(ii) determining the contributions of canid populations to the test canid genome by comparing the alleles in the test canid genome to a database comprising canid population profiles, wherein each canid population profile comprises genotype information for the set of markers in the canid population.
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Specification